1.The Socio-Demographic and Clinical Factors Associated with Quality of Life among Patients with Haematological Cancer in a Large Government Hospital in Malaysia
Das Priscilla ; Awang Hamidin ; Md Zain Azhar ; Kon Noorjan ; Md Said Salmiah ; Khalid Bahariah
Malaysian Journal of Medical Sciences 2011;18(3):49-56
Background: The paper examined the quality of life of haematological cancer patients
according to their socio-demographic profiles and clinical diagnoses.
Methods: This cross-sectional study was conducted at the tertiary referral centre of Ampang
Hospital, Kuala Lumpur, involving 105 patients. The European Organisation for Research and
Treatment of Cancer Quality of Life (EORTC QLQ-C30) questionnaire was used to measure their
quality of life.
Results: The study involved patients diagnosed with all types of haematological cancer,
including non-Hodgkin lymphoma (NHL), acute myelogenous leukaemia (AML), acute lymphoblastic
leukaemia (ALL), Hodgkin lymphoma (HL), and multiple myeloma (MM), with a response rate of
83.3%. The patients with ALL, HL, without NHL, and without MM were younger than other patients.
There were significant differences in quality of life scores in different socio-demographic groups
and types of cancer diagnosis. The global quality of life of the female patients was much better than
that of the male patients. Patients who were 40 years old or younger had a better global quality
of life and physical functioning, as well as fewer symptoms of constipation, nausea, and vomiting.
Employed patients were in less pain but showed greater impairments of cognitive function than
did unemployed patients. Patients who earned a monthly wage of RM1000 or less had reduced
physical function, more symptoms of pain, and more financial difficulties compared with patients
who earned more. Patients with AML tended to have better physical functioning than did patients
with MM, whose physical functioning was impaired. Comparatively, more symptoms of dyspnoea
were found in ALL and HL patients than in other types of lymphoma. Compared with other patients,
those with ALL had a greater loss of appetite, and other lymphoma patients had fewer symptoms of
pain. Patients with NHL had impaired role functioning and more constipation compared with other
patients. The results were all statistically significant (P < 0.05).
Conclusion: The quality of life of haematological cancer patients is affected by sociodemographic
factors and clinical diagnoses. Efforts should be made to improve the overall quality of
life of these patients.
2.CROSS SECTIONAL STUDY: STRESS, DEPRESSION, ANXIETY AND COPING STYLES AMONG MALAYSIAN UNIVERSITY STUDENTS
Priscilla Das ; Palaniammal Kissen@Krishnan
Journal of University of Malaya Medical Centre 2022;25(1):158-163
Introuduction:
Psychiatric symptoms such as depression and anxiety can have a strong impact on mental health status.
Objectives:
The study aimed to determine the prevalence and associated factors of stress, depression, and anxiety
in relation to coping styles among university students.
Methods:
A self-administered questionnaire consisting of socio-demographic information, Depression Anxiety Stress Scales (DASS)-21 and the Brief-Coping Orientation to Problems Experienced (COPE) inventory was used. The
collected data were analyzed, and descriptive statistics and correlational tests were applied in this study.
Results:
The majority of respondents were female (n=84). A total of 100 university students aged from 18-44 years
old were included in the study. The students were pursuing either a bachelor (n=33), diploma (n=66) or master’s
program (n=1). About 26% of the respondents had different grades of stress with 12%, 6% and 8% of respondents
experiencing mild, moderate and severe degrees of stress respectively. The results also showed that 33% of the
respondents had different grades of depression with 10%, 13%, 5% having mild, moderate and severe degrees of
depression respectively. Another 5% had extremely severe depression. As many as 61% of the respondents had
different grades of anxiety with mild (8%), moderate (25%), severe (9%) and extremely severe (19%) degrees of anxiety. Stress was associated with venting coping styles (r=0.287; p=0.004), behavioral disengagement (r=0.425;
p<0.001) and self-blame (r=0.469; p<0.001). Depression correlated with behavioral disengagement (r=0.383;
p<0.001) and self-blame (r=0.375; p<0.001) and correlated negatively with positive reframing (r=-0.221; p=0.027).
Finally, anxiety had a significant relationship with behavioral disengagement (r=0.383; p<0.001) and self-blame
(r=0.403; p<0.001).
Conclusion
Maladaptive coping styles such as venting, behavioral disengagement and self-blame have a significant
impact on increased stress, anxiety and depression levels among university students.
Mental Disorders