1.A Case of Successful Gestational Outcome in the Presence of Preterm-labor Due to Hematometro-colpos of Obstructed Hemivagina and Uterus Didephys.
Seung Man KIM ; Cheol Seong BAE ; Hyeo Won YOON
Korean Journal of Perinatology 1997;8(4):425-432
Uterine didelphys with unilateral hematometra, hemicolpos, and ipsilateral renal agenesis is a rare m01lerian duct malformation. Uterine didelphys with an obstructed hemivagina is frequently associated with renal agenesis, mostly ipsilateral to the blind vaginal pouch. Accurate early diagnosis and septal resection elevate pregnancy rate and birth rate but it is difficult to find these malfomations until the complication associated with pregnancy was developed. We report a case of successful gestational outcome in the presence of preterm labor due to hematometrocolpora caused by uterine didelphys with unilateral imperforated vagina and ipsilateral renal agenesis with brief review of the literatures.
Birth Rate
;
Early Diagnosis
;
Female
;
Hematometra
;
Obstetric Labor, Premature
;
Pregnancy
;
Pregnancy Rate
;
Uterus*
;
Vagina
2.Cumulative live birth rates after frozen embryo transfer and fresh embryo transfer with oocyte numbers more than 15.
Journal of Central South University(Medical Sciences) 2019;44(2):158-163
To compare the cumulative live birth rates (CLBR) and the incidence of ovarian hyperstimulation syndrome (OHSS) between fresh embryo transfer (ET) and frozen ET (the freeze-all policy), when oocyte numbers are more than 15 in the first treatment of in vitro fertilization or intracytoplasmic sperm injection, and to evaluate the benefits of the freeze-all policy.
Methods: We retrospectively analyzed clinical data of 2 842 patients whose oocytes numbers were more than 15, including 1 095 frozen ET patients and 1 747 fresh ET patients. The patients general data, a baseline features, CLBR, and the incidence of OHSS were compared between the 2 groups.
Results: There were 598 patients in the 2 groups after they experienced the propensity score matching. No significant differences were found in age, infertility causes, body mass index, basal follicle stimulating hormone level, the total days and total dose of using gonadotrophin (Gn) between the 2 groups (all P>0.05). The CLBR of the freeze-all cycles increased along with the number of oocytes (P>0.05), and the oocyte numbers were greater in freeze-all group than those of the fresh ET group (P<0.001). There was no significant difference in CLBR after one complete cycle between the 2 groups (P>0.05), but after the first embryo transfer cycle, the CLBR in freeze-all group was higher than that in the fresh ET cycle group (P<0.05). The incidence of OHSS in patients with freeze-all was significantly lower than that in the patiants with fresh ET (P<0.05).
Conclusion: Patients with oocytes over 15 and OHSS tendency who accepted the freeze-all strategy can help them to prevent OHSS and they have a higher CLBR than fresh ET cycles.
Birth Rate
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Embryo Transfer
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Female
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Fertilization in Vitro
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Humans
;
Oocytes
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Pregnancy
;
Pregnancy Rate
;
Retrospective Studies
3.Intrauterine insemination with donor sperm: only the number of motile spermatozoa inseminated influences both pregnancy and live-birth rates.
Marie CARDEY-LEFORT ; Berengere DUCROCQ ; Audrey UK ; Helen BEHAL ; Anne-Laure BARBOTIN ; Geoffroy ROBIN
Asian Journal of Andrology 2022;24(3):287-293
Intrauterine insemination with donor sperm (IUI-D) is an assisted reproductive technology (ART) offered to couples with definitive male infertility or risk of genetic disease transmission. Here, we sought to evaluate our practice in IUI-D and identify factors that influenced the success rate. We performed a retrospective, single-center study of all IUI-D procedures performed at Lille University Medical Center (Lille, France) between January 1, 2007, and December 31, 2017. Single and multivariate analyses with a mixed logistic model were used to identify factors associated with clinical pregnancies and live births. We included 322 couples and 1179 IUI-D procedures. The clinical pregnancy rate was 23.5%, and the live birth rate was 18.9% per IUI-D. In a multivariate analysis, the women's age was negatively associated with the live birth rate. The number of motile spermatozoa inseminated was the only factor associated with both clinical pregnancies and live births, with a chosen threshold of 0.75 million. The clinical pregnancy and live birth rates were, respectively, 17.3% and 13.0% below the number of motile spermatozoa inseminated threshold and 25.9% and 21.0% at or above the threshold (all P = 0.005). The number of motile spermatozoa inseminated was the only factor that significantly influenced both pregnancies and live-birth rates after IUI-D. Indeed, below a threshold of 0.75 million motile spermatozoa inseminated, those rates were significantly lower. Application of this number of motile spermatozoa inseminated threshold may help centers to allocate donations more effectively while maintaining reasonable waiting times for patients.
Birth Rate
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Female
;
Humans
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Insemination
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Insemination, Artificial
;
Male
;
Pregnancy
;
Pregnancy Rate
;
Retrospective Studies
;
Spermatozoa
4.Reproductive Outcome of Women with Recurrent Abortions or Infertility Following Treatment by Operative Hysteroscopy for an Intrauterine Septum.
Ji Hong SONG ; Keun Jai YOO ; In Ok SONG ; Eun Chan PAIK ; Bum Chae CHOI ; Il Pyo SON ; Jong Young JUN ; In Sou PARK ; Mi Kyoung KOONG ; In Soo KANG
Korean Journal of Obstetrics and Gynecology 1998;41(12):3034-3039
Uterine anomalies have been reported in 4% of women with infertility and in up to 15% of those with recurrent abortion. One of the major intrauterine disorder associated with infertility and recurrent abortions is intrauterine septum, The reproductive outcome of 41 patients of intrauterine septum (7 complete, 34 incomplete) with repeated abortions or infertility was assessed after the uterine septotomy. 5 of 7 patients with comlete uterine septum undergone uterine septotomy (3; hysteroscopic metroplasty, 2; abdominal metroplasty) had total 6 pregnancies and all of them had live biths. 28 patients with incomplete uterine septum got the hysteroscopic intrauterine septotomy and the viable pregnancy rate was 62% (3 ongoing pregnancies, 13 live biths of total 26 pregnancies). 6 patients with incomplete uterine septum had not the operation and 5 patients had 5 live births after total 6 pregnancies with 1 spontaneus abortion. Even though, the number of cases were small, the live birth rate in the group of septotomy of the patients of complete uterine septum (100%, 6/6) was higher than that in the group of not-done (50%, 1/2). The live birth rate in the group of not-done of the patients with incomplete uterine septum (83%, 5/6) was higher than that in the group of hysteroscopic uterine septotomy (62%, 16/26), but 5 of 6 had short uterine septal length (<1 cm), 1 had 1.5 cm septal length in the group of not-done. All the patients with successful pregnancy outcome had no other co-factors at the diagnostic laparoscopy, but the 5 primary infertility patients with no live birth even after treatment (all were with incomplete septum; 3 undergone hysteroscopic septotomy, 2 not-done with one abortion) had other co-factors such as endometriosis, peritoneal or tubal facor. In conclusion, hysteroscopic uterine septotomy would be useful for the patients with habitutal abortion or infertility and more advanced managemnet protocols should be applied to the patients having other co-factors if there was no pregnancy even after the uterine septotomy.
Abortion, Habitual*
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Endometriosis
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Female
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Humans
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Hysteroscopy*
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Infertility*
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Laparoscopy
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Live Birth
;
Pregnancy
;
Pregnancy Outcome
;
Pregnancy Rate
5.A study on comparison of pregnancy rate according to the previous sterilization method.
Yeong Cheul CHOI ; Tae Sun KIM
Korean Journal of Obstetrics and Gynecology 1993;36(7):954-962
No abstract available.
Pregnancy Rate*
;
Pregnancy*
;
Sterilization*
6.A study of pregnancy rate after myomectomy.
Byung Min LEE ; Yong Jin NA ; Dong Hee PARK ; Man Soo YOON ; Won Whe KIM
Korean Journal of Obstetrics and Gynecology 1993;36(8):3241-3249
No abstract available.
Pregnancy Rate*
;
Pregnancy*
7.A clinical study on pregnancy rate following tubal reversal.
Whan Goo LEE ; Im Soon LEE ; Kwon Hae LEE ; Tai Ho CHO
Korean Journal of Fertility and Sterility 1993;20(3):217-224
No abstract available.
Pregnancy Rate*
;
Pregnancy*
8.Epidural anesthetic management of achondroplastic parturient dwarf undergoing cesarean section: A case report.
Se Hun LIM ; Chee Mahn SHIN ; Young Jae KIM ; Kun Moo LEE ; Jeong Han LEE ; Kwang Rae CHO ; Myoung Hun KIM ; Shin Hae CHANG
Anesthesia and Pain Medicine 2012;7(2):181-184
Achondroplasia is the most common non-lethal skeletal dysplasia. Underdevelopment and premature ossification of bones result in characteristic craniofacial and spinal abnormalities. Achondroplastic dwarfs have low fertility rates and require delivery by cesarean section due to their cephalo-pelvic disproportion. Controversy exists regarding the ideal anesthesia for an achondroplastic parturient dwarf for urgent cesarean section. Anesthesia, whether general or regional, presents many potential problems during cesarean section. We report the experience of the epidural anesthesia in an achondroplastic dwarf undergoing elective cesarean section.
Achondroplasia
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Anesthesia
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Anesthesia, Epidural
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Birth Rate
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Cesarean Section
;
Female
;
Pregnancy
9.Statistical Investigation of Each Variable of Fetal Heart Rate According to Birth Weight.
Hoo Yoen CHUNG ; Mool Il PARK ; Dong Yul SHIN ; Jee Soo PARK ; Sung Ro CHUNG ; Hyoung Sun SHIN ; Kyung Joon CHA
Korean Journal of Perinatology 2000;11(2):170-178
No abstract available.
Birth Weight*
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Female
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Fetal Heart*
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Heart Rate, Fetal*
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Parturition*
;
Pregnancy
10.In vitro fertilization and embryo transfer may improve live birth rate for patients with intrauterine adhesions after hysteroscopic adhesiolysis.
Dan SUN ; Xingping ZHAO ; Huan HUANG ; Aiqian ZHANG ; Wenwei CHENG ; Yimin YANG ; Dabao XU
Journal of Central South University(Medical Sciences) 2022;47(11):1559-1567
OBJECTIVES:
The prevalence of intrauterine adhesion (IUA) increased gradually, which seriously affected female reproductive health and fertility. This study aims to analyze the clinical features of pre-, intra-, and post hysteroscopic adhesiolysis (HA) and to identify the main risk factors for non-live birth and other factors affecting pregnancy outcome in patients with IUA.
METHODS:
A total of 486 IUA patients with reproductive needs, who underwent HA in the third Xiangya Hospital of Central South University from January 2017 to May 2018, were retrospectively included. The follow-up period was 2-3 years after operation. Univariate analysis and multivariate logistic regression analysis were used to explore the relationship between clinical features and live birth rate in patients with IUA. Pre-operative clinical indicators included age, gravidity, parity, abortion, IUA recurrence, menstrual patterns, and disease course. Intraoperative clinical features assessed in the last operation were uterine cavity length, IUA appearance, IUA area, number of visible uterine cornua, number of visible tubal ostia, and American Fertility Society (AFS) scores. The relationship between clinical indicators and postoperative live birth rate was investigated by univariate analysis and multivariate logistic regression analysis. Pregnancy pattern was the main variable.
RESULTS:
Among the 486 IUA patients included in this study, there were 256 (52.67%) live births and 230 (47.33%) non-live births. Univariate analysis and multivariate logistic regression showed that the live birth rate of in vitro fertilization and embryo transfer (IVF-ET) after HA was higher than that of spontaneous pregnancy (OR=0.557, 95% CI 0.361 to 0.861, P=0.008). When the bilaterally fallopian tube ostia were invisible in the last operation (OR=0.322, 95% CI 0.104 to 0.997, P=0.049), patients were more likely to have live birth. The older the patient was, the lower the live birth rate was (OR=1.081, 95% CI 1.034 to 1.131, P<0.001). The live birth rate would be low when the last AFS score was moderate (OR=2.973, 95% CI to 1.541 to 5.738, P<0.010).
CONCLUSIONS
Based on the outcome of the first pregnancy after HA, IUA patients' pregnancy patterns, age, number of visible tubal ostia, and AFS scores noted by a second-look hysteroscopy, are the factors influencing the prognosis for the live birth rate in IUA patients. IVF-ET may improve live birth rate for patients with IUA after HA.
Humans
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Female
;
Pregnancy
;
Birth Rate
;
Retrospective Studies
;
Embryo Transfer