1.Analysis of closed abdominal injury in pregnant women.
Chang-di TU ; Shao-juan WANG ; Ri-guang ZHOU ; Yang-yi WEI ; Qiang TAN
Chinese Journal of Traumatology 2005;8(4):205-208
OBJECTIVETo explore the characteristics of closed abdominal injury in pregnancy women and its treatment.
METHODSThe clinical data of 37 pregnancy patients with closed abdominal injury treated in our hospital from June 1993 to June 2003 were collected and analyzed.
RESULTSAll the 37 patients were treated with operation. Among them 2 early pregnancy patients with intestinal rupture and 1 patient with retroperitoneal hematoma were treated under laparoscope; in other 34 pregnancy patients laparotomy was performed. Of the 34 patients 8 used cesarean section because premature separation of placenta and enlarged womb interrupted the management of intra-abdominal organ injury. In the 37 patients 33 (89.1%) were cured, 4 (10.8%) die, postoperative complication rate was 16.2% (6/37). Two patients (5.4%) suffered from abdominal cavity infection, 3 (8.1%) from pulmonary infection, and 1 (2.7%) had multi-organ failure.
CONCLUSIONSFor pregnancy patients with closed abdominal injury, besides obsteric diseases intra-abdominal injury should be given much attention. Accurate diagnosis and timely treatment can gain the time to save the life of both mother and fetus.
Abdominal Injuries ; diagnosis ; surgery ; Adult ; Female ; Humans ; Laparoscopy ; Pregnancy ; Pregnancy Complications ; diagnosis ; surgery
2.Clinical analysis of 244 cases with abdominal wall endometriosis.
Xue Ting PEI ; Yan WANG ; Ling Hui CHENG ; Hong Yan LI ; Xu Qing LI
Chinese Journal of Obstetrics and Gynecology 2023;58(11):818-825
Objective: To investigate the clinical characteristics, diagnosis, treatment, outcomes and prognostic factors of abdominal wall endometriosis (AWE). Methods: A total of 265 AWE patients who underwent surgical treatment in The First Affiliated Hospital of Anhui Medical University from January 2010 to April 2023 were retrospectively selected, and 244 patients had complete follow-up data. According to different depth of lesions, the enrolled patients were divided into three types: type Ⅰ (subcutaneous fat layer, n=30), type Ⅱ (anterior sheath muscle layer, n=174) and type Ⅲ (peritoneum layer, n=40). The general clinical features, perioperative conditions, recurrent outcome and prognostic factors were analyzed in three types. Results: (1) Compared with type Ⅲ patients, the age of onset, parity and incidence of pelvic endometriosis were significantly decreased in type Ⅱ patients [(32.0±4.0) vs (30.0±4.6) years, 1.6±0.6 vs 1.4±0.5, 10.0% (4/40) vs 1.7% (3/174), respectively; all P<0.05], while the proportion of patients with transverse incision was significantly increased [37.5% (15/40) vs 67.3% (115/171); P<0.01]. The first symptoms of type Ⅰ and type Ⅱ were mainly palpable mass in the abdominal wall [73.3% (22/30), 63.2% (110/174), respectively], but the first symptom of type Ⅲ was pain in the abdominal wall [55.0% (22/40); all P<0.05]. (2) No matter the results of preoperative B-ultrasound or intraoperative exploration, the lesion diameters of type Ⅰ, type Ⅱ and type Ⅲ showed significant upward trends (all P<0.05). The proportions of lesion diameter≥3 cm in type Ⅱ and type Ⅲ [67.8% (118/174), 80.0% (32/40)] were significantly higher than that in type Ⅰ (all P<0.05). The median operation time and blood loss of type Ⅰ and Ⅱ were significantly lower than those of type Ⅲ (type Ⅰ vs type Ⅲ: 37.5 vs 50.0 minutes, 10 vs 20 ml, all P<0.05; type Ⅱ vs type Ⅲ: 35.0 vs 50.0 minutes, 10 vs 20 ml, all P<0.05). (3) The median follow-up time was 49 months, the overall symptom remission rate was 98.4% (240/244), and the recurrence rate was 7.0% (17/244). There were no significant differences in recurrence rate and recurrence free time among three types (all P>0.05). Multivariate regression analysis showed that the depth, number, diameter of lesions and postoperative adjuvant medication were not significant factors for postoperative recurrence (all P>0.05). Conclusions: The clinical manifestations of type Ⅲ are the most serious, including obvious abdominal pain symptoms, larger lesion diameter, prolonged operation time, increased intraoperative blood loss and increased incidence of pelvic endometriosis. Complete resection of lesions is an effective treatment for AWE, with high symptom remission rate and low recurrence rate. The depth, number, diameter of lesions and postoperative adjuvant medication are not risk factors for recurrence.
Pregnancy
;
Female
;
Humans
;
Adult
;
Endometriosis/surgery*
;
Retrospective Studies
;
Abdominal Wall/pathology*
;
Risk Factors
;
Abdominal Pain
3.Old Abdominal Pregnancy Presenting as an Ovarian Neoplasm.
Mi Suk KIM ; Soyoon PARK ; Tae Sung LEE
Journal of Korean Medical Science 2002;17(2):274-275
Abdominal pregnancy is extremely rare, but even more unusual is the prolonged retention of an advanced abdominal pregnancy with lithopedion formation. The presentation of lithopedion as an ovarian tumor without a symptom has not been reported in Korea. A 63-yr-old, gravida 2, para 1, woman was referred to us with an abominal mass. Pelvic examination revealed normal postmenopaused uterus and a fetal head-sized movable hard mass in the lower abdomen. The computed tomographic scan showed a densely echogenic mass of 10-cm in diameter as an ovarian neoplasm. Laparotomy disclosed a lithopedion, of which the bones and cartilages were well preserved. There have been controversies on the treatment of lithopedion. Although some cases are stable for a long time, the morbidity increases when the operation is performed in an elderly patient. So we believe that the surgical intervention should be done as soon as possible after thorough consideration of the morbidity and the risk.
Female
;
Humans
;
Middle Aged
;
Ovarian Neoplasms/*etiology/radiography/surgery
;
Pregnancy
;
Pregnancy, Abdominal/radiography/*surgery
;
Tomography, X-Ray Computed/methods
4.Primary peritoneal pregnancy implanted on the uterosacral ligament: a case report.
Joong Sik SHIN ; Young Jin MOON ; Seung Ryong KIM ; Kyung Tai KIM ; Hyung MOON ; Youn Yeung HWANG
Journal of Korean Medical Science 2000;15(3):359-362
Peritoneal pregnancies are classified as primary and secondary. Primary implantation on the peritoneum is extremely rare in extrauterine pregnancy and is a potentially life-threatening variation of ectopic pregnancy within the peritoneal cavity, representing a grave risk to maternal health. Secondary abdominal pregnancies are by far the most common and result from tubal abortion or rupture, or less often, after uterine rupture with subsequent implantation within abdomen. Early diagnosis and appropriate surgical management, regardless of stage of gestation, appear to be important in achieving good results. We report a case of primary peritoneal pregnancy in a 28-year-old woman, who had severe lower abdominal pain one day before laparotomy for a preoperative diagnosis of ectopic pregnancy. The conceptus was implanted on the left uterosacral ligament. A fresh embryo of approximately 8 weeks' gestation was found in the conceptus.
Adult
;
Case Report
;
Female
;
Follow-Up Studies
;
Hemoperitoneum/surgery
;
Hemoperitoneum/diagnosis
;
Hemoperitoneum/complications*
;
Human
;
Ligaments
;
Ovum Implantation
;
Peritoneum/pathology
;
Pregnancy
;
Pregnancy, Abdominal/surgery
;
Pregnancy, Abdominal/pathology
;
Pregnancy, Abdominal/diagnosis
;
Pregnancy, Abdominal/complications*
;
Rupture, Spontaneous/surgery
;
Rupture, Spontaneous/diagnosis
;
Sacrum
;
Uterus/pathology
5.Abdominal malignant melanoma complicating pregnancy: report of a case.
Chinese Journal of Pathology 2013;42(12):845-845
Abdominal Wall
;
Adult
;
Female
;
Follow-Up Studies
;
Humans
;
Melanoma
;
pathology
;
surgery
;
Pregnancy
;
Pregnancy Complications, Neoplastic
;
pathology
;
surgery
;
Skin Neoplasms
;
pathology
;
surgery
6.Clinics in diagnostic imaging (106). Viable left tubal twin ectopic pregnancy.
Singapore medical journal 2005;46(11):651-655
Live twin ectopic gestations are extremely rare. There are more than 100 reported twin tubal pregnancies but less than ten have foetal cardiac motions demonstrated in both embryos. We describe an additional patient with live twin ectopic gestation. A 32-year-old woman presented with increasing left-sided abdominal pains. She had a high beta-hCG level and a significant history of subfertility with previous surgical intervention. Transvaginal ultrasonography showed viable left tubal twin ectopic pregnancy. The diagnosis was confirmed at surgery. Factors that contribute to the risk of ectopic pregnancy, diagnosis and the management of this condition are described.
Abdominal Pain
;
etiology
;
Adult
;
Female
;
Fertility Agents
;
Humans
;
Live Birth
;
Obstetric Surgical Procedures
;
Pregnancy
;
Pregnancy, Tubal
;
diagnostic imaging
;
physiopathology
;
surgery
;
Reproductive Techniques, Assisted
;
Risk Factors
;
Twins
;
Ultrasonography
7.Uterine epithelioid trophoblast tumor: report of a case.
Mei-fu GAN ; Chun-kai YU ; Hong-sheng LU ; Pei-nong YANG
Chinese Journal of Pathology 2007;36(8):570-571
Abdominal Neoplasms
;
secondary
;
surgery
;
Abdominal Wall
;
Antiporters
;
metabolism
;
Choriocarcinoma
;
pathology
;
Diagnosis, Differential
;
Epithelioid Cells
;
pathology
;
Female
;
Gestational Trophoblastic Disease
;
metabolism
;
pathology
;
secondary
;
surgery
;
Humans
;
Pregnancy
;
Uterine Neoplasms
;
metabolism
;
pathology
;
surgery
;
Young Adult
8.Repairment of the large wound of endometriosis in the abdominal wall.
Ke-xin SONG ; Zhu-feng LIU ; Ru ZHAO ; Xiao-jun WANG ; Qun QIAO
Acta Academiae Medicinae Sinicae 2005;27(6):753-755
OBJECTIVETo explore the plastic surgical repairment of the large wound of endometriosis in the abdominal wall.
METHODSince March 2003 to December 2004, 6 patients were treated with abdominoplasty and V-Y plasty for the wounds of the endometriosis in the abdominal wall.
RESULTSThe endometriotic foci were removed thoroughly with pretty abdominal contour. No complications were observed.
CONCLUSIONAbdominoplasty and V-Y plasty are good methods to repair the wounds of the endometriosis in the abdominal wall.
Abdominal Wall ; surgery ; Adult ; Cesarean Section ; adverse effects ; Endometriosis ; etiology ; surgery ; Female ; Follow-Up Studies ; Humans ; Pregnancy ; Reconstructive Surgical Procedures ; methods ; Surgical Flaps
9.Efficacy of low extra-abdominal aortic block in cesarean section for placenta accreta spectrum disorders and its effect on the expression of MDA and SOD.
Ruizhen LI ; Moothoosamy SOMASODIRAN ; Tao SUN ; Chunxia CHEN ; Mailian LONG ; Dabao XU
Journal of Central South University(Medical Sciences) 2022;47(8):1129-1135
OBJECTIVES:
Placenta accreta spectrum disorders (PAS) refers to a group of abnormalities in placental adhesion and invasion, which may lead to serious complications such as intractable postpartum hemorrhage. The use of low-level extra-abdominal aortic temporary block during cesarean section may reduce intraoperative bleeding in patients with PAS, but it may also cause ischemia-reperfusion injury. In this study, we intend to investigate the efficacy of low extra-abdominal aortic block in cesarean section for placental implantation disease and its effect on malondialdehyde (MDA) level and superoxide dismutase (SOD) activity, and analyze the severity of ischemia-reperfusion injury caused by them.
METHODS:
Pregnant women with invasive placenta accreta spectrum disorders who delivered in the Department of Obstetrics and Gynecology of the Third Xiangya Hospital of Central South University from July 2017 to July 2021, were selected, and they were divided into 2 groups. Group A consisted of those who underwent low extra-abdominal aortic block during cesarean section (n=15) and group B consisted of those who did not undergo extra-abdominal aortic block (n=15). The intraoperative bleeding, blood transfusion, hysterectomy and complication rate, postoperative hospital stay and hospitalization expenses were compared between the 2 groups to analyze the efficacy of abdominal aortic block. The biochemical indexes related to ischemia-reperfusion, MDA content and total superoxide dismutase (T-SOD) activity, were measured at the corresponding time points in both groups. The time points of each test were: in group A, before the block of the low extra-abdominal aorta after delivery (A0), 0 h (A1, when the myometrium was started to be sutured), 0.5 h (A2), 2 h (A3), and 4 h (A4) after the open block; in group B, after delivery of the fetus (B0), 0 h (B1), 0.5 h (B2), 2 h (B3), and 4 h (B4) after the myometrium was started to be sutured. Total duration of abdominal aortic block in group A was also recorded. Both groups were observed for sings of edema, ischemia, necrosis and infection in the limbs after surgery. The severity of ischemia-reperfusion injury caused by abdominal aortic block were determined by detecting the relevant biochemical indexes at different moments of reperfusion.
RESULTS:
The intraoperative bleeding and blood transfusion in group A were less than those in group B, and the difference was statistically significant (P<0.05). There was no significant difference in postoperative hospital stay and hospitalization expenses between the 2 groups (P>0.05). Surgical complications: in group A, the uterus was preserved in all cases, there was 1 bladder injury and 2 pelvic infections; while in group B, there was 1 hysterectomy, 3 bladder injuries, and 3 pelvic infections. Changes in T-SOD and MDA values: compared with A0 before block, the MDA level was significantly elevated in blood at time points A1, A2, and A3, while SOD activity was significantly decreased (P<0.05), and the 2 observed indexes basically returned to A1 level (ischemic period) at 4 h after open block (A4). There was no significant difference in the changes of T-SOD and MDA in group B (P>0.05). Comparison of T-SOD and MDA levels between group A and B: the difference of the 2 indexes was not statistically significant between A0 and B0 (P>0.05), MDA level was not statistically significant between A1 and B1, T-SOD activity at A1 was lower than B1, the difference was statistically significant, at the rest of the same time point, MDA level in group A were higher than that in group B, T-SOD activity in group A were lower than that in group B, the difference was statistically significant (P<0.05). No postoperative limb edema, ischemia, necrosis, or infection occurred in both groups.
CONCLUSIONS
Low-level extra-abdominal aortic block effectively reduces bleeding and transfusion during cesarean section for placenta accreta spectrum disorders, resulting in a transient MDA elevation and a decrease of SOD activity, which means causing transient ischemia-reperfusion injury without complications such as limb edema, ischemia, necrosis, and infection.
Aorta, Abdominal/surgery*
;
Cesarean Section
;
Female
;
Humans
;
Ischemia
;
Necrosis
;
Pelvic Infection
;
Placenta/metabolism*
;
Placenta Accreta/surgery*
;
Pregnancy
;
Reperfusion Injury
;
Superoxide Dismutase/metabolism*
10.Degeneration of Leiomyoma in Patients Referred for Uterine Fibroid Embolization: Incidence, Imaging Features and Clinical Characteristics.
Seung Chul HAN ; Man Deuk KIM ; Dae Chul JUNG ; Myungsu LEE ; Mu Sook LEE ; Sung Il PARK ; Jong Yun WON ; Do Yun LEE ; Kwang Hun LEE
Yonsei Medical Journal 2013;54(1):215-219
PURPOSE: Imaging features and clinical characteristics of degenerated leiomyoma in patients referred for uterine fibroid embolization (UFE) were analyzed to assess the incidence of degenerated leiomyoma. MATERIALS AND METHODS: Patients referred for UFE between 2008 and 2009 were retrospectively analyzed (n=276). Patients ranged in age from 27 to 51 years (mean 38.0 years). All patients underwent screening MRI with contrast enhancement. Medical histories and clinical symptoms were evaluated. RESULTS: Among the 276 patients who underwent MRI, 14 (5.1%) showed degenerated leiomyomas. Symptoms were abdominal pain (n=4, 26.7%), menorrhagia (n=5, 35.7%) and bulk-related symptoms (n=5, 35.7%) and no symptoms (n=5, 35.7%). Of the 14 patients with degenerated leiomyomas, 5 (42.9%) had a history of pregnancy in the past two years. For T1-weighted imaging (T1WI), a high signal intensity (SI) of the leiomyoma was the most common finding (n=9, 64.3%) and a hyperintense rim (n=4, 28.6%) was the second most common. On T2-weighted imaging (T2WI), a low SI of the leiomyoma was found in six patients (42.9%), a high SI in four (28.6%) and a heterogeneous SI in four (28.6%) patients. Conservative management was performed in 11 (78.6%) patients, surgery in 3 (21.4%) and uterine artery embolization in one (7.1%) patient. CONCLUSION: The incidence of degeneration of leiomyoma in patients referred for UFE was 5.1%. Patients presented with variable clinical symptoms with or without a history of pregnancy. MR imaging showed a high SI on T1WI and various SIs on T2WI without contrast enhancement. An understanding of the degeneration of leiomyomata is essential when considering UFE.
Abdominal Pain/therapy
;
Adult
;
Female
;
Follow-Up Studies
;
Humans
;
Incidence
;
Leiomyoma/*complications/epidemiology/*pathology/*surgery
;
Magnetic Resonance Imaging
;
Menorrhagia/therapy
;
Middle Aged
;
Pregnancy
;
Retrospective Studies
;
Treatment Outcome
;
*Uterine Artery Embolization