4.A Case of CD7+, CD4-, CD8-, CD3-acute T cell lymphoblastic leukemia.
Hee Jin HUH ; Jung Won HUH ; Mi Yae LEE ; Woon Sup HAN ; Wha Soon CHUNG
Korean Journal of Clinical Pathology 2001;21(4):260-263
A CD7 positive acute leukemia, lacking CD4, CD8, CD3, CD13 and CD33 expression may include 4 categories; acute T-cell leukemia, mixed lineage leukemia, acute undifferentiated leukemia and CD7 positive acute myeloid leukemia. Therefore, the expression of cyCD3 or the presence of TCR gene rearrangement can make the diagnosis of acute T-cell leukemia. We report a patient with acute T-cell lymphoblastic leukemia, showing CD7+, CD4-CD8-, and CD3-expression and TCR gamma gene rearrangement.
Diagnosis
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Genes, T-Cell Receptor
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Genes, T-Cell Receptor gamma
;
Humans
;
Leukemia
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Leukemia, Myeloid, Acute
;
Precursor Cell Lymphoblastic Leukemia-Lymphoma*
;
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
;
T-Lymphocytes
5.Transfusion - Associated Graft - Versus - Host Disease in Patients with Acute Leukemia.
Myung Soo CHA ; Kwang Hoon LEE ; Yoo Hong MIN ; Kwang Gil LEE
Korean Journal of Dermatology 1996;34(2):345-349
Graft-versus-host disease can develop in immunosuppressed individuals who receive blood product transfusions that contain imrnunocompetent lymphocytes. We report a case of transfusion-associated graft-versus-host disease(TA-GVHD) that developed in a patient with acute lymphocytic leukemia who were undergoing therapy. The groups at risk for development of TA-GVHD, the clinical presentation and course, and methods of diagnosis are summarized. Prevention of TA-CVHD is possible by irradiation of blood products given to patients at risk, but problems remain in determining the groups that warrant such measures. We should be aware of the risk of developing TA-GVHD after routine blood transfusion, especially in areas where the population's HLA types are rather homogeneous.
Blood Transfusion
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Diagnosis
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Graft vs Host Disease
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Humans
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Leukemia*
;
Lymphocytes
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Precursor Cell Lymphoblastic Leukemia-Lymphoma
;
Transplants*
6.Posttraumatic Growth of Adolescents with Childhood Leukemia and their Parents.
Sungsil HONG ; Ho Ran PARK ; Sun Hee CHOI
Child Health Nursing Research 2019;25(1):9-16
PURPOSE: Childhood leukemia is a serious trauma affecting both adolescents and their parents, who experience painful process. However, adolescents with leukemia and their parents also experience positive changes, which is referred to as posttraumatic growth. We examined posttraumatic growth, core beliefs, impact of event, and event-related rumination in adolescents within 5 years of a diagnosis of childhood leukemia and their parents. METHODS: The participants were 68 adolescents with childhood leukemia (aged 13~18 years) and their parents, who were recruited from C university hospital in Korea from May to September 2016. The Posttraumatic Growth Inventory, Core Belief Inventory, Impact of Event Scale-Revised, and Event-related Rumination Inventory were completed by the adolescents and their parents. The mean scores and correlations between variables were investigated for both set of participants. RESULTS: Parents showed significantly higher levels of posttraumatic growth, disruption of core beliefs, impact of event, and invasive rumination than adolescents. Disruption of core beliefs and deliberate rumination were positively correlated with posttraumatic growth in both groups. CONCLUSION: Nursing intervention programs that involve modifying core beliefs and inducing a positive thought can help adolescents with leukemia and their parents grow after traumatic events.
Adolescent*
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Diagnosis
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Humans
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Korea
;
Leukemia*
;
Nursing
;
Parents*
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Precursor Cell Lymphoblastic Leukemia-Lymphoma
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Stress Disorders, Post-Traumatic