1.Abnormal Mitral Regurgitation Flow Velocity Spectra by Continuous Wave Doppler in Flail Mitral Valve.
Jong Hoa BAE ; Maylene WONG ; Pravin M SHAH
Korean Circulation Journal 1986;16(2):233-241
No abstract available.
Mitral Valve Insufficiency*
;
Mitral Valve*
2.Systolic Pressure Gradients in Aortic Valve Stenosis by Continuous Wave Doppler Echocardiography.
Jong Hoa BAE ; G VIJAYARAGHAVAN ; Pravin M SHAH
Korean Circulation Journal 1985;15(1):45-52
No abstract available.
Aortic Valve Stenosis*
;
Aortic Valve*
;
Blood Pressure*
;
Echocardiography, Doppler*
3.Experimental Study of Pressure - Velocity Relationship Across Stenotic Orifices by Continuous Wave Doppler Ultrasound.
Jong Hoa BAE ; Maylene WONG ; G VIJAYARAGHAVAN ; Pravin M SHAH
Korean Circulation Journal 1985;15(1):37-44
No abstract available.
Ultrasonography*
4.A Simple Two-Dimensional Echocardiographic Sign of Tricuspid Regurgitation.
Jong Hoa BAE ; Chuwa TEI ; G VIJAYARAGHAVAN ; George CHERIAN ; Pravin M SHAH
Korean Circulation Journal 1985;15(2):269-276
No abstract available.
Echocardiography*
;
Tricuspid Valve Insufficiency*
5.Symptomatic improvement with gluten restriction in irritable bowel syndrome: a prospective, randomized, double blinded placebo controlled trial.
Vinay G ZANWAR ; Sunil V PAWAR ; Pravir A GAMBHIRE ; Samit S JAIN ; Ravindra G SURUDE ; Vinaya B SHAH ; Qais Q CONTRACTOR ; Pravin M RATHI
Intestinal Research 2016;14(4):343-350
BACKGROUND/AIMS: The existence of non-celiac gluten sensitivity has been debated. Indeed, the intestinal and extra-intestinal symptoms of many patients with irritable bowel syndrome (IBS) but without celiac disease or wheat allergy have been shown to improve on a gluten-free diet. Therefore, this study set out to evaluate the effects of gluten on IBS symptoms. METHODS: We performed a double-blind randomized placebo-controlled rechallenge trial in a tertiary care hospital with IBS patients who fulfilled the Rome III criteria. Patients with celiac disease and wheat allergy were appropriately excluded. The participants were administered a gluten-free diet for 4 weeks and were asked to complete a symptom-based questionnaire to assess their overall symptoms, abdominal pain, bloating, wind, and tiredness on the visual analog scale (0-100) at the baseline and every week thereafter. The participants who showed improvement were randomly assigned to one of two groups to receive either a placebo (gluten-free breads) or gluten (whole cereal breads) as a rechallenge for the next 4 weeks. RESULTS: In line with the protocol analysis, 60 patients completed the study. The overall symptom score on the visual analog scale was significantly different between the two groups (P<0.05). Moreover, the patients in the gluten intervention group scored significantly higher in terms of abdominal pain, bloating, and tiredness (P<0.05), and their symptoms worsened within 1 week of the rechallenge. CONCLUSIONS: A gluten diet may worsen the symptoms of IBS patients. Therefore, some form of gluten sensitivity other than celiac disease exists in some of them, and patients with IBS may benefit from gluten restrictions.
Abdominal Pain
;
Celiac Disease
;
Diet
;
Diet, Gluten-Free
;
Edible Grain
;
Glutens*
;
Humans
;
Irritable Bowel Syndrome*
;
Prospective Studies*
;
Tertiary Healthcare
;
Visual Analog Scale
;
Wheat Hypersensitivity
;
Wind
6.Symptomatic improvement with gluten restriction in irritable bowel syndrome: a prospective, randomized, double blinded placebo controlled trial.
Vinay G ZANWAR ; Sunil V PAWAR ; Pravir A GAMBHIRE ; Samit S JAIN ; Ravindra G SURUDE ; Vinaya B SHAH ; Qais Q CONTRACTOR ; Pravin M RATHI
Intestinal Research 2016;14(4):343-350
BACKGROUND/AIMS: The existence of non-celiac gluten sensitivity has been debated. Indeed, the intestinal and extra-intestinal symptoms of many patients with irritable bowel syndrome (IBS) but without celiac disease or wheat allergy have been shown to improve on a gluten-free diet. Therefore, this study set out to evaluate the effects of gluten on IBS symptoms. METHODS: We performed a double-blind randomized placebo-controlled rechallenge trial in a tertiary care hospital with IBS patients who fulfilled the Rome III criteria. Patients with celiac disease and wheat allergy were appropriately excluded. The participants were administered a gluten-free diet for 4 weeks and were asked to complete a symptom-based questionnaire to assess their overall symptoms, abdominal pain, bloating, wind, and tiredness on the visual analog scale (0-100) at the baseline and every week thereafter. The participants who showed improvement were randomly assigned to one of two groups to receive either a placebo (gluten-free breads) or gluten (whole cereal breads) as a rechallenge for the next 4 weeks. RESULTS: In line with the protocol analysis, 60 patients completed the study. The overall symptom score on the visual analog scale was significantly different between the two groups (P<0.05). Moreover, the patients in the gluten intervention group scored significantly higher in terms of abdominal pain, bloating, and tiredness (P<0.05), and their symptoms worsened within 1 week of the rechallenge. CONCLUSIONS: A gluten diet may worsen the symptoms of IBS patients. Therefore, some form of gluten sensitivity other than celiac disease exists in some of them, and patients with IBS may benefit from gluten restrictions.
Abdominal Pain
;
Celiac Disease
;
Diet
;
Diet, Gluten-Free
;
Edible Grain
;
Glutens*
;
Humans
;
Irritable Bowel Syndrome*
;
Prospective Studies*
;
Tertiary Healthcare
;
Visual Analog Scale
;
Wheat Hypersensitivity
;
Wind
Result Analysis
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