1.A rare case of Nonsyndromic Oligodontia with Ankyloglossia
Reshma Suvarna ; Prasanna Kumar Rao ; Raghavendra Kini ; Devika Shetty ; Vidya Holla
Pacific Journal of Medical Sciences 2018;18(1):56-60
Agenesis of teeth and ankyloglossia are common human developmental anomalies. Terms like Oligodontia, Anodontia and Hypodontia are used to describe agenesis of teeth. Oligodontia is a rare condition generally defined as agenesis of six or more teeth excluding the third molars. The condition is not frequently documented in Indian children. There is no much documentation on oligodontia with ankylogossia. Ankyloglossia can adversely affect the development of the surrounding structures including the alveolar process, teeth and can impair functions such as mastication, speech, and swallowing. The present article reports a rare case of non-syndromic oligodontia associated with ankyloglossia in an 8-year old male patient. Oligodontia is a relatively rare condition affecting 0.1-0.2% of the population. Our present case is even rare because of its association with ankyloglossia
2.Cheiloscopy as an additional forensic parameter : a review
Dhanya S. Rao ; I. M Ali ; Rajeshwari G. Anniger ; Ujwala Shetty ; Prasanna Kumar Rao ; Raghavendra Kin
Pacific Journal of Medical Sciences 2017;17(1):46-51
Criminal activities involving human life always puts lives at stake. Newer advances in other fields especially medicine and dentistry is essential in solving the mysteries of death. Different disciplines insert a part of the puzzle until it is complete. Fingerprints, DNA profiling, Forensic anthropology are commonly employed in personnel identification, mass disasters and others. Investigators may also rely on lip prints to identify possible suspects or to support evidence gained in specific investigations. A lip print at scene of crime can be the basis for inference as to the number of people involved, gender, habits, occupational traits, and others, based on the pathological changes present. This review deals with lip prints and their possible acquisition and usage.
3.Effects of prematuration culture with a phosphodiesterase-3 inhibitor on oocyte morphology and embryo quality in in vitro maturation
Mohammed Ashraf CHERUVEETIL ; Prasanna Kumar SHETTY ; Kamini A RAO ; Arya RAJENDRAN ; Muhammed ASIF
Clinical and Experimental Reproductive Medicine 2021;48(4):352-361
The study assessed the developmental potential of germinal vesicle (GV) oocytes subjected to in vitro maturation (IVM) after prematuration culture with cilostamide (a phosphodiesterase-3 inhibitor) and the impact of cilostamide exposure on the morphology of meiosis II (MII) oocytes and subsequent embryo quality. Methods: In total, 994 oocytes were collected from 63 patients. Among 307 GV oocytes, 140 oocytes were selected for the experimental group and 130 oocytes for the control group. The denuded GV-stage oocytes were cultured for 6 hours with cilostamide in the experimental group and without cilostamide in the control group. After 6 hours, the oocytes in the experimental group were washed and transferred to fresh IVM medium. The maturational status of the oocytes in both groups was examined at 26, 36, and 48 hours. Fertilization was assessed at 18 hours post-intracytoplasmic sperm injection. Embryo quality was assessed on days 3 and 5. Results: In total, 92.1% of the oocytes remained in the GV stage, while 6.4% converted to the MI stage (p<0.01) after cilostamide exposure. In both groups, more MII oocytes were observed at 36 hours (25.8% vs. 21.5%) than at 26 hours (10.8% vs. 14.6%) and 48 hours (13% vs. 7.9%) (p>0.05). With the advent of cilostamide, blastocyst quality was better in the experimental group than in the control group (p<0.05). Conclusion: Cilostamide effectively blocked nuclear maturation and promoted cytoplasmic growth. Prematuration culture with cilostamide enabled synchronization between cytoplasmic and nuclear maturity, resulting in better blastocyst outcomes.