1.Evidence on the prevention of postoperative endophthalmitis
Philippine Journal of Ophthalmology 2005;30(2):85-87
CLINICAL SCENARIO: An 82-year-old female with no apparent ocular problems, except fora brunescent cataract, underwent phacoemulsification with intraocular-lens (IOL) implantation. Postoperative medication consisted solely of antibiotic-steroid eye drops. One day after uneventful surgery, the patient developed severe pain, poor vision, and redness in the operated eye. Visual acuity was counting fingers at 1 meter. The eye had ciliary injection, grade 4 flare and cells, a small hypopyon, fibrin extending from the corneal wound, and a mildly edematous cornea. Intraocular pressure (IOP) was 24 mm Hg. Exudates behind the IOL were noted, but visualization was poor. Anterior-chamber and vitreous taps revealed gram-positive cocci. Could the ophthalmologist have prevented this complication? CLINICAL QUESTION: Among patients undergoing cataract extraction, what is the most effective regimen that can reduce the risk of endophthalmitis? SEARCH METHOD: A Medline search was performed using the keywords "endophthalmitis," "cataract," and "prevention." The search was limited to randomized controlled trials (RCT). No studies were found that compared endophthalmitis rates using different perioperative prophylactic measures. Most studies reported used substitute outcome measures such as periocular bacterial load, intraocular penetration of antibiotics, and anterior-chamber contamination. After reviewing the abstracts, only one RCT was considered relevant to the clinical question CITATION: Soto AM, Mendivil MP. The effect of topical povidone-iodine, intraocular vancomycin, or both on aqueous humor cultures at the time of cataract surgery. Ophthalmol 2001; 131:293-300. (Author)
PHACOEMULSIFICATION, VANCOMYCIN, POVIDONE-IODINE
2.Determination of the microbiologic flora on the inclusion site among obstetric patients who underwent surgical skin preparation with either 10% povidone iodine or 4% chlorhexidine antiseptic solution prior to cesarean section in a tertiary hospital
Diana J. Cupino ; Stella Marie L. Jose
Philippine Journal of Obstetrics and Gynecology 2018;42(1):9-15
Objectives:
To determine the microbiologic flora after surgical skin preparation of the incision site using either chlorhexidine or povidone iodine antiseptic solution prior to cesarean section among obstetric patients.
Materials and Methods:
This is a cross-sectional study of ninety-two (92) obstetric patients who were admitted for cesarean section. They underwent fishbowl lottery, wherein participants drew from a bag of folded stubs written chlorhexidine or povidone iodine, to determine their distribution to either group. Forty six (46) participants were distributed in each group. Skin cultures were obtained by the researchers from the incision site after surgical skin preparation using chlorhexidine or povidone iodine.
Results:
Total of 92 participants enrolled in this study, 46 participants in chlorhexidine group and another 46 participants in povidone iodine group. There was no statistically significant difference between the 2 groups in terms of clinicodemographic characteristics. Out of the 92 participants, only one participant, under the povidone iodine group, showed a growth of 100,000 colony-forming units of Enterobacter cloacae and has no statistical significance in the growth of microbiologic flora after effective surgical skin preparation with either chlorhexidine or povidone iodine.
Conclusions
This study showed that chlorhexidine and povidone iodine are both effective in eliminating microbiologic flora after surgical skin preparation prior to cesarean section. Povidone iodine is still a sound choice of antiseptic especially in low resource setting. Due to the descriptive nature of this paper, only assumptions that chlorhexidine and povidone iodine are comparable antiseptic solutions can be deduced from this study.
Cesarean Section
;
Povidone-Iodine
3.Chronic exit-site care using povidone-iodine versus normal saline in peritoneal dialysis patients.
Kidney Research and Clinical Practice 2014;33(3):119-120
No abstract available.
Humans
;
Peritoneal Dialysis*
;
Povidone-Iodine*
4.Salivary Bacterial Counts after Application of Povidone-Iodine and Chlorhexidine.
Seo Yoon KIM ; Ki Pyo NOH ; Hak Kyun KIM ; Su Gwan KIM ; Joong Ki KOOK ; Soon Nang PARK ; Min Jung KIM ; Jae Jin KIM ; Eun Seok KIM
Journal of the Korean Association of Oral and Maxillofacial Surgeons 2009;35(5):312-315
OBJECTIVE: It is important to sterilize oral cavity with antibacterial agent before surgery for preventing infection. The object of this study was to compare the effect on reduction of salivary bacterial counts according to applied time when povidone-iodine (PVI) and chlorhexidine gluconate (CHX), most broadly used materials in dentistry, were applied intraorally before the surgery. METHODS: Sixty subjects were divided into 6 groups. PVI and CHX were applied in each group for 1, 2 and 3 minutes, respectively. Then salivary microbacteria taken before and after applying the materials were cultured using 5% sheep blood agar plate. RESULTS: There was significant difference in reduction of microbacteria in both PVI and CHX and the effect did not show differences depending on time. When applied for a minute, PVI showed somewhat higher reduction rate than CHX, but in the other groups, there was no difference in reduction rate. CONCLUSION: We found that there was no significant difference in sterilization ability of PVI and CHX in all groups in this study. Therefore, both agents would get sufficient effect when applied for a minute.
Agar
;
Bacterial Load
;
Chlorhexidine
;
Dentistry
;
Mouth
;
Povidone-Iodine
;
Sheep
;
Sterilization
5.Salivary Bacterial Counts after Application of Povidone-Iodine and Chlorhexidine.
Seo Yoon KIM ; Ki Pyo NOH ; Hak Kyun KIM ; Su Gwan KIM ; Joong Ki KOOK ; Soon Nang PARK ; Min Jung KIM ; Jae Jin KIM ; Eun Seok KIM
Journal of the Korean Association of Oral and Maxillofacial Surgeons 2009;35(5):312-315
OBJECTIVE: It is important to sterilize oral cavity with antibacterial agent before surgery for preventing infection. The object of this study was to compare the effect on reduction of salivary bacterial counts according to applied time when povidone-iodine (PVI) and chlorhexidine gluconate (CHX), most broadly used materials in dentistry, were applied intraorally before the surgery. METHODS: Sixty subjects were divided into 6 groups. PVI and CHX were applied in each group for 1, 2 and 3 minutes, respectively. Then salivary microbacteria taken before and after applying the materials were cultured using 5% sheep blood agar plate. RESULTS: There was significant difference in reduction of microbacteria in both PVI and CHX and the effect did not show differences depending on time. When applied for a minute, PVI showed somewhat higher reduction rate than CHX, but in the other groups, there was no difference in reduction rate. CONCLUSION: We found that there was no significant difference in sterilization ability of PVI and CHX in all groups in this study. Therefore, both agents would get sufficient effect when applied for a minute.
Agar
;
Bacterial Load
;
Chlorhexidine
;
Dentistry
;
Mouth
;
Povidone-Iodine
;
Sheep
;
Sterilization
6.Morphologic study of the ototoxicity of povidone-iodine preparation to the guinea pig middle ear.
Joong Gahng KIM ; Jong Hoon KIM ; Byung Hoon AHN ; Kwan Kyu PARK
Korean Journal of Otolaryngology - Head and Neck Surgery 1993;36(4):624-632
No abstract available.
Animals
;
Ear, Middle*
;
Guinea Pigs*
;
Guinea*
;
Povidone-Iodine*
7.Methods used in the study, Evaluation of a polyurethane foam dressing impregnated with 3% povidone-iodine (Betafoam) in a rat wound model, led to unreliable results.
Annals of Surgical Treatment and Research 2018;95(4):230-232
No abstract available.
Animals
;
Bandages*
;
Methods*
;
Polyurethanes*
;
Povidone-Iodine*
;
Rats*
;
Wounds and Injuries*
8.Efficacy of the Clindamycin Mouthwash on Oral Flora.
Seong Wook LEE ; Hong Lim DO ; Hyun Chul CHO ; Hoon Shik YANG ; Young Ho HONG ; Hoon KIM ; Chun Gil KIM
Korean Journal of Otolaryngology - Head and Neck Surgery 1997;40(2):204-209
Systemic antibiotic therapy is widely used for prophylaxis in major head and neck surgery, but the efficacy of topical oral antibiotic therapy has not been fully investigated. Therefore we planned to study the efficacy of topical clindamycin gargle on oral flora. Thirty-six healthy adults(20 males, 16 females) were included in the study, and we tried with three oral-washing agents; 0.9% normal saline, 10% povidone iodine, and 75mg clindamycin in 52ml tap water. Samples of saliva were cultured for aerobic and anaerobic bacteria immediately before, immediately after, and at 1- and 4-hour intervals after, washing the mouth with a solution of either control(normal saline or povidone iodine) or clindamycin. Quantitative analysis demonstrated significant reduction of oral flora level after use of the topical antibiotic at the 1-, 4-, and 8- hour interval. It is postulated that topical clindamycin, by reducing concentrations of oral flora, may also reduce the incidence of regional infection following major upper aerodigestive tract surgery.
Anti-Bacterial Agents
;
Bacteria, Anaerobic
;
Clindamycin*
;
Head
;
Humans
;
Incidence
;
Male
;
Mouth
;
Neck
;
Povidone
;
Povidone-Iodine
;
Saliva
;
Water
9.Two Cases of Allergic Contact Dermatitis due to Povidone-iodine.
Ill Hwan KIM ; Kee Chan MOON ; Soo Nam KIM
Korean Journal of Dermatology 1985;23(6):780-784
Povidone-iodine (PVP-I) is a widely used antiseptic for the skin and mucous membrane. It is known that povidone-iodine rarely induce contact sensitization. Recently, we have experienced 2 cases of povidone-iodine contact dermatitis. Standard patch test with PUP-I, PVP and, iodine were performed.
Dermatitis, Allergic Contact*
;
Dermatitis, Contact
;
Iodine
;
Mucous Membrane
;
Patch Tests
;
Povidone-Iodine*
;
Skin
10.Allergic contact dermatitis due to topical medicaments in Korea.
Hong Jig KIM ; Kyeong Joon HYEON ; Hong Eil KUK ; Hai Min CHOI ; Kee Chan MOON ; Choong Rim HAW ; Soo Chan KIM ; Hee Chul EUN ; Chung Won KIM ; Hyung Ok KIM ; Young Pio KIM ; Eil Soo LEE
Korean Journal of Dermatology 1991;29(1):32-40
No abstract available.
Acne Vulgaris
;
Allergens
;
Dermatitis, Allergic Contact*
;
Dermatitis, Contact
;
Hospitals, University
;
Incidence
;
Korea*
;
Mass Screening
;
Merbromin
;
Patch Tests
;
Potassium
;
Povidone
;
Povidone-Iodine