Objective: To investigate the toxicity of methanol extract of various parts (Root, Stem, Leaf, Flower and Fruit) of Lantana camara(L. Camara) in Artemia salina. Methods: The methanol extracts of L. camara were tested for in vivo brine shrimp lethality assay. Results: All the tested extract exhibited very low toxicity on brine shrimp larva. The results showed that the root extract was the most toxic part of L. camara and may have potential as anticancer agent. Conclusions:Methanolic extract of L. camara is relatively safe on short-term exposure.

OBJECTIVETo investigate the toxicity of methanol extract of various parts (Root, Stem, Leaf, Flower and Fruit) of Lantana camara (L. Camara) in Artemia salina.

METHODSThe methanol extracts of L. camara were tested for in vivo brine shrimp lethality assay.

RESULTSAll the tested extract exhibited very low toxicity on brine shrimp larva. The results showed that the root extract was the most toxic part of L. camara and may have potential as anticancer agent.

CONCLUSIONSMethanolic extract of L. camara is relatively safe on short-term exposure.

Animals ; Artemia ; drug effects ; Dose-Response Relationship, Drug ; Lantana ; chemistry ; Lethal Dose 50 ; Plant Components, Aerial ; chemistry ; Plant Extracts ; toxicity ; Plant Roots ; chemistry

OBJECTIVETo investigate the antioxidant activity of methanolic extracts of Lantana camara (L. camara) various parts and the determination of their total phenolics content.

METHODSThe extract was screened for possible antioxidant activities by free radical scavenging activity(DPPH), xanthine oxidase inhibition activity and Griess-Ilosvay method.

RESULTSThe results showed that all the plant parts possessed antioxidant properties including radical scavenging, xanthine oxidase inhibition and nitrites scavenging activities. The antioxidative activities were correlated with the total phenol. The leaves extract of L. camara was more effective than that of other parts.

CONCLUSIONSThis study suggests that L. camara extracts exhibit great potential for antioxidant activity and may be useful for their nutritional and medicinal functions.

Allopurinol ; pharmacology ; Antioxidants ; pharmacology ; Chronic Disease ; drug therapy ; Free Radical Scavengers ; pharmacology ; Humans ; Lantana ; chemistry ; Methanol ; Oxidation-Reduction ; Oxidative Stress ; drug effects ; Phenols ; pharmacology ; Phytotherapy ; methods ; Plant Extracts ; pharmacology ; Plant Leaves ; chemistry ; Plant Roots ; chemistry ; Plant Stems ; chemistry ; Plants, Medicinal ; chemistry ; Reactive Oxygen Species ; Solvents