1.Therapeutic Effect of Potassium Iodide in Erythema Nodosum.
Chong Seong LEE ; Kwang Joong KIM ; Eil Soo LEE
Korean Journal of Dermatology 1986;24(5):602-605
We evaluated the therapeutic effect of potassium iodide in fourteen patients with erythema nodosum. The results were as follows: 1) All patients were given a saturated solution of potassium iodide, 600 to 900 mg orall y a day for 3 days to 5 weeks. 2) Three patients were observed initial days, two patients within 9 days. 3) There were no correlations between therapeutic effect of potassium iodide. 4) Specific side effects were not found during the treatment with potassium iodide.
Erythema Nodosum*
;
Erythema*
;
Humans
;
Potassium Iodide*
;
Potassium*
2.Six Cases of Sporotrichosis Treated with Potassium Iodide and Itraconazole.
Yoon Whoa CHO ; Chang Kwun HONG ; Kye Yong SONG ; Byung In RO
Annals of Dermatology 1992;4(2):128-132
We report 6 cases of sporotricosis including 3 cases of lymphocutaneous type and 3 cases of fixed cutaneous type. There were 3 males and 3 females patients in the age between 5 to 63 year-old age. Clinically, histopathologically and mycologically, we diagnosed the cases as the sporotrichosis. And then case 1 and 2 were treated with potassium iodide for 9 weeks and 15 weeks duration. Case 3, 4, 5 and 6 were treated with itraconazole for 10-14 weeks duration. All patients were almost healed without recurrence.
Female
;
Humans
;
Itraconazole*
;
Male
;
Potassium Iodide*
;
Potassium*
;
Recurrence
;
Sporotrichosis*
3.A Case of Sporotrichosis.
Gong Myung HYUN ; Yang Cha PARK ; Jin Tack KIM
Korean Journal of Dermatology 1976;14(2):147-151
Sporotrichosis is an infection of worldwide distribution caused by the fungal organiam sporotrichum schenckii. The disease is usually of the primary cutaneous variety with involvement of regionaI lymphatics, although dissemination may occur. A case of lymphatic type of Syorotrichosis affecting 33 years old, barber, who has been suffering from painless multiple nodules on right hand 4 forearm, is presented. The skin lesions developed about 3months ago, and increased sise and numbers of the lesion insidiously. Diagnosis was confirmed by characterietic clinical, mycological, histopathological studies He was treated with potassium iodide and there was markedly improved.
Adult
;
Diagnosis
;
Forearm
;
Hand
;
Humans
;
Potassium Iodide
;
Skin
;
Sporothrix
;
Sporotrichosis*
4.A Study on the Changes of Clinical Findings in Sporotrichosis for Recent 30 Years.
Chae Sung YIM ; Kyung Sool KWON ; Ho Sun JANG ; Tae Ahn CHUNG ; Chang Keun OH
Korean Journal of Medical Mycology 1997;2(1):43-49
BACKGROUND: The clinical types of sporotrichosis are generally classified into four groups: lymphocutaneous, fixed cutaneous, and cutaneous disseminated, and hematogenous. Of these, the lymphocutaneous variety is the most frequently encountered pattern, constituting 80% of sporotrichosis patients and the fixed cutaneous sporotrichosis is the next Potassium iodide (KI) was the most commonly used drug for the treatment of sporotrichosis. Many studies about these clinical findings of sporotrichosis have been reported, but comparative study on the changes in clinical findings has not been reported. OBJECTIVE: The purpose of this study is to clarify the changes of the clinical findings in sporotrichosis in Korea. METHODS: A total of 58 patients with sporotrichosis who had visited the Department of Dermatology, Pusan National University were divided into 2 groups according to the period and then the clinical findings of sporotrichosis were compared. RESULTS: The results of study are summarized as follows: 1. During this period, there were 58 cases of sporot.ichosis. In the past period (1967~1979) there were 35 cases of sporot.ichosis, and there were 23 cases in the recent period (1980 ~1997). 2. In the past period, most cases (71.4%) were lymphocutaneous type, however in the recent period, most cases (69.2%) were fixed cutaneous type. 3. The most commonly affected site was right upper extremity in the past period, but face & right upper extremity were the most commonly affected sites in the recent period. 4. In the past period, 2nd and 3rd decades were prevalent age group, but 5th to 7th decades were prevalent age group in the recent period. 5. In the treatment of sporotrichosis, potassium iodide (KI) was the choice of treatment in the past period, however itraconazole is gradually used in the recent period. CONCLUSION: According to this study, many changes in clinical findings of sporotrichosis were noted, especially in the clinical type. We found that conical type of sporotrichosis changed from lymphocutaneous type to the fixed cutaneous type with time. And we suggest that further observation would be necessary to define the meaning of these changes.
Busan
;
Dermatology
;
Humans
;
Itraconazole
;
Korea
;
Potassium Iodide
;
Sporotrichosis*
;
Upper Extremity
5.Nail Avulsion by Potassium Iodide Treatment in Onychomycosis.
Kwang KIM ; Kyung Sool KWON ; Tae Ahn CHUNG
Korean Journal of Dermatology 1982;20(6):845-851
The effect of 50 per cent potassium iodide (KI) ointment with occlusive dressing on onychomycosis of the fingers and toes was studiei in 54 patients with 176 diseased nails. The results obtained were as follows. 1. Of a total of 76 fingernails and 100 toenails in 54 patients, all fingernails and toenails showed an excellent response with easy removal of the diseased nails. 2. The duration that the occluded KI aintment remained in place before successful avulsion was 6. 6 (range, 3 to 18) days for fingernails, and 6. 8 (range, 3 to 20) days for toenails with onychomycosis. 8. Of 16 nails of control group which were treated with vaseline, none showed the significant improvement. 4. The problems during this treatment were; mild irritation and/or itching (9 cases), and pin-point bleeding on curettage of nail bed (18 cases). It is suggested that the KI treatment has many advantages and seemed to be an ideal method of treatment of onychomycosis.
Curettage
;
Fingers
;
Hemorrhage
;
Humans
;
Nails
;
Occlusive Dressings
;
Onychomycosis*
;
Petrolatum
;
Potassium Iodide*
;
Potassium*
;
Pruritus
;
Toes
6.A Case of Sweet's Syndrome Treated with Potassium Iodide.
Jin Hyoung KIM ; Yeon Soon LIM ; Hae Young CHOI ; Ki Bum MYUNG
Korean Journal of Dermatology 1999;37(8):1074-1078
Sweet's syndrome(acute neutrophilic dermatosis) is characterized by raised, painful red plaques with pseudoblistering and pustules on the face, neck, chest, and extremities accompanied by fever, polymorphonuclear neutrophilic leukocytosis, and elevated ESR. We report a case successfully treated with potassium iodide in which showed tender indurated erythematous papules, nodules, plaques, and several overlying vesicles with fever and general malaise. These lesions had frequently recurred in spite of oral corticosteroid administration for 5 months at a local clinic. The cutaneous eruptions subsided 7 days after administration of a saturated potassium iodide solution and have not recurred to date.
Extremities
;
Fever
;
Leukocytosis
;
Neck
;
Neutrophils
;
Potassium Iodide*
;
Potassium*
;
Sweet Syndrome*
;
Thorax
7.Four Cases of Sporotrichosis Treated with Low Dose of Potassium Iodide.
Ghi Seob LIM ; Myeung Nam KIM ; Sun Wha LEE ; Byung In RO ; Chin Yo CHANG
Korean Journal of Dermatology 1985;23(6):799-804
We experienced four cases of sporotrichosis including three lymphocutaneous type and one fixed cutaueous type. Case 1 was a 6-year old child, affected over the right chin. Case 2 was a 31-year old housewife, affected over the right forearm, Case 3 was a 53-year old housewife, affected over the right forearm and dorsum of right hand. Case 4 was a 19-year old student, affected over the left forearm. Histopathologically, chronic granulomatous inflammation with the neutrophilic ivfiltration and/or central suppuration were observed. Mycologically, typical colonies with moist, wrinkled and rnembraneous surface were cultured except in case 3. All patients were completly cured by oral administration of low dosage of potassium iodide(63. R-lllg) in a short period (50~86 days).
Administration, Oral
;
Adult
;
Child
;
Chin
;
Forearm
;
Hand
;
Humans
;
Inflammation
;
Middle Aged
;
Neutrophils
;
Potassium Iodide*
;
Potassium*
;
Sporotrichosis*
;
Suppuration
;
Young Adult
8.Inhibition of nicotine-induced Streptococcus mutans biofilm formation by salts solutions intended for mouthrinses
Abdulrahman A BALHADDAD ; Mary Anne S MELO ; Richard L GREGORY
Restorative Dentistry & Endodontics 2019;44(1):e4-
OBJECTIVES: Biofilm formation is critical to dental caries initiation and development. The aim of this study was to investigate the effects of nicotine exposure on Streptococcus mutans (S. mutans) biofilm formation concomitantly with the inhibitory effects of sodium chloride (NaCl), potassium chloride (KCl) and potassium iodide (KI) salts. This study examined bacterial growth with varying concentrations of NaCl, KCl, and KI salts and nicotine levels consistent with primary levels of nicotine exposure. MATERIALS AND METHODS: A preliminary screening experiment was performed to investigate the appropriate concentrations of NaCl, KCl, and KI to use with nicotine. With the data, a S. mutans biofilm growth assay was conducted using nicotine (0–32 mg/mL) in Tryptic Soy broth supplemented with 1% sucrose with and without 0.45 M of NaCl, 0.23 M of KCl, and 0.113 M of KI. The biofilm was stained with crystal violet dye and the absorbance measured to determine biofilm formation. RESULTS: The presence of 0.45 M of NaCl, 0.23 M of KCl, and 0.113 M of KI significantly inhibited (p < 0.05) nicotine-induced S. mutans biofilm formation by 52%, 79.7%, and 64.1%, respectively. CONCLUSIONS: The results provide additional evidence regarding the biofilm-enhancing effects of nicotine and demonstrate the inhibitory influence of these salts in reducing the nicotine-induced biofilm formation. A short-term exposure to these salts may inhibit S. mutans biofilm formation.
Biofilms
;
Dental Caries
;
Gentian Violet
;
Mass Screening
;
Nicotine
;
Potassium Chloride
;
Potassium Iodide
;
Salts
;
Sodium Chloride
;
Streptococcus mutans
;
Streptococcus
;
Sucrose
9.A Case of Perforating Granuloma Annulare.
Yong Kee SEONG ; Kwang Hyun CHO ; Seon Hoon KIM ; Yoo Shin LEE
Korean Journal of Dermatology 1986;24(5):678-681
We present a case of perforating granuloma annulare which appeared as multiple small papular lesions with central umbilication on the dorsum of both foot and sides of foot, The patient was a 12 year-old female child who had slightly tender lesions of one month's duration. Histologic study showed perforation of the epiderrnis and release of the abnormal necrobiotic material transepiderrnally. The epidermal perforation communicated with area of granuloma annulare in the dermis that consist of necrobiotic collagen surrounded by palisading mononucler phagocytes in the dermis. All the lesions resolved spontaneously with a slight hyperpigmentation in 4 months. She also had erythematous tender nodules, which diagnosed as erythema nodosum, on both shins. The lesions responded to potassium iodide 1.0g for 2 weeks.
Child
;
Collagen
;
Dermis
;
Erythema Nodosum
;
Female
;
Foot
;
Granuloma Annulare*
;
Granuloma*
;
Humans
;
Hyperpigmentation
;
Phagocytes
;
Potassium Iodide
10.In vitro senstivity of sporothrix schenckii against antifungal agents.
Moo Kyu SUH ; Yeol Oh SUNG ; Hwa Sung KIM
Korean Journal of Dermatology 1993;31(6):884-889
BACKGROUND: Despite concern about treatment of sporotrichosis, little is known about the sensitivity of S. schenckii against antifungal agents. OBJECTIVE: The purpose of the study was to investigate minimal irihibitory concentration(MIC) of antifungal agents against S.chenckii. METHOD: The tested strains were seven in number. The tested antifngal agents were ketoconazole, itraconazole, amphotericin B, and potassium iodide. A various concentration of drugs were mixed into fluid media containing 50% ethanol, dimethyl sulfoxide, and distilled water. The inoculum consisted of 3mm block containing hyphae and spores. RESULTS: MIC ranges of ket.oconazole, itraconazole, amphotericin B, and potassium iodide were 0.39- 25pg/ml, 0.78-25pg/ml, 0.78-25pg/ml, and 75-550pg/ml, respectively. CONCLUSION: We find that ketoconazole is the most active drug against S. schenckii.
Amphotericin B
;
Antifungal Agents*
;
Dimethyl Sulfoxide
;
Ethanol
;
Hyphae
;
Itraconazole
;
Ketoconazole
;
Potassium Iodide
;
Spores
;
Sporothrix*
;
Sporotrichosis
;
Water