Transient hyperkalemia is well known to occur in man following intravenous administration of succinylcholine chloride. We studied the change of the serum potassium concentration after injection of succinylcholine in nonburn patients and electricburn patients, physical status 1 or 2 adopted by the American Society of Anesthesiologists. We compared two groups: Non-burn patient group(Group 1) as control, Electric burn patient group (Group 2) as experimental. The following results were obtained: 1) In non-burn patient group(Group 1) serum potassium concentration was slightly decreased in the 1st, 2nd, 3rd, 4th, 5th, 6th and 10th minute after succinylcholine injection compared with control, but nostatistical significance was noticed in this group. 2) In electric burn patient group (Group 2) serum potassium concentration was maximally increased compared with the controls. Statistical significance was noticed at the 2nd and 3rd minute after succinylcholine injection in this group.
Administration, Intravenous ; Burns, Electric* ; Humans ; Hyperkalemia ; Potassium ; Succinylcholine*

Fritillaria thunbergii is a commonly used traditional Chinese medicine, which has the effects of clearing heat and resolving stagnation, eliminating phlegm and relieving cough. At present, it is mostly produced by cultivation, and the cultivation process requires application of base fertilizer, winter fertilizer, seedling fertilizer and late top dressing. Now farmyard manure or organic fertilizer can be used to replace the base fertilizer and winter fertilizer, but the research on the replacement of organic fertilizer has not been completed for the late top dressing. Potassium fulvate is a kind of fulvate fertilizer, which can not only regulate the growth of crops but also supplement potassium necessary for the growth of crops. In this paper, using F. thunbergii as a model plant with mature cultivation techniques, the effect of potassium fulvate on the quality and yield of rhizome traditional Chinese medicine F. thunbergii was systematically studied for the first time. HPLC-ELSD was used to determine the contents of peimine A and peimine B, hot dip method was used to determine the content of alcohol extract, and the SPAD-502 Plus chlorophyll meter was used to detect SPAD value. The results showed that applying 1.5 to 2.25 kg·hm~(-2) of potassium fulvic acid per hectare could effectively improve the yield of F. thunbergii and there was significantly difference between potassium phosphate monobasic and potassium fulvic acid in terms of quality. After the application of range 1.5 to 2.25 kg·hm~(-2) of potassium fulvic acid per hectare, the content of alcohol soluble extract of F. thunbergii was ranged 21.61% to 22.27%, the total amount of peimine A and peimine B were ranged 0.09% to 0.10%. Applying 1.5 to 2.25 kg·hm~(-2) of potassium fulvic acid per hectare could replace the conventional pure chemical fertilizer potassium phosphate monobasic, which could be used as top dressing fertilizer for the cultivation of F. thunbergii.
Benzopyrans/administration & dosage* ; Fertilizers ; Fritillaria/chemistry* ; Phytochemicals/analysis* ; Potassium/administration & dosage*

We experienced four cases of sporotrichosis including three lymphocutaneous type and one fixed cutaueous type. Case 1 was a 6-year old child, affected over the right chin. Case 2 was a 31-year old housewife, affected over the right forearm, Case 3 was a 53-year old housewife, affected over the right forearm and dorsum of right hand. Case 4 was a 19-year old student, affected over the left forearm. Histopathologically, chronic granulomatous inflammation with the neutrophilic ivfiltration and/or central suppuration were observed. Mycologically, typical colonies with moist, wrinkled and rnembraneous surface were cultured except in case 3. All patients were completly cured by oral administration of low dosage of potassium iodide(63. R-lllg) in a short period (50~86 days).
Administration, Oral ; Adult ; Child ; Chin ; Forearm ; Hand ; Humans ; Inflammation ; Middle Aged ; Neutrophils ; Potassium Iodide* ; Potassium* ; Sporotrichosis* ; Suppuration ; Young Adult

PURPOSE: The Aim of this study was to find the value of intravesical permeability of potassium as a diagnostic measure of the interstitial cystitis and to find importance of intravesical mucosal layer by intravesical instillation of potassium chloride solution. MATERIALS AND METHODS: 20 patients with interstitial cystitis and 20 normal subjects without UTI, frequency and urgency underwent intravesical challenge with 40ml water and 40ml of 400meq/L potassium chloride solution. After 5 minutes, patients were asked about increase or decrease of urgency or suprapubic pain and subjective response of urgency or suprapubic pain were recorded on a scale of 0 to 5. RESULTS: Neither normal subjects nor patients with interstitial cystitis reacted to water administered intravesically. There was marked sensitivity to intravesical potassium in 85% of patients with interstitial cystitis versus 10% of normal controls (p<0.05). CONCLUSIONS: Diffusion of urinary potassium ion into the bladder interstitium may induce sensory symptoms, damage the tissue and be a major toxic factor in the pathogenesis of interstitial cystitis. Intravesical potassium sensitivity can be a reliable method for detecting abnormal epithelial permeability and useful diagnostic test for interstitial cystitis.
Administration, Intravesical ; Cystitis, Interstitial* ; Diagnosis* ; Diagnostic Tests, Routine ; Diffusion ; Humans ; Permeability* ; Potassium Chloride ; Potassium* ; Urinary Bladder ; Water

Administration, Oral ; Adult ; Drug-Related Side Effects and Adverse Reactions ; nursing ; Female ; Humans ; Potassium Permanganate ; administration & dosage ; poisoning ; Powders

OBJECTIVE: To determine the application of modified low-potassium dextran (LPD) solution in heart-lung transplantation. METHODS: We used the modified LPD as the lung flush solution of the donor in the first heart-lung transplantation procedure in Hunan. RESULTS: The patient survived 555 days after the surgery and severe infection, lung disfunction or severe graft rejection never occurred. CONCLUSION Modified LPD as lung flush solution of the donor during heart-lung transplantation demonstrates an excellent effect of lung protection.
Adult ; Dextrans ; administration & dosage ; Heart Defects, Congenital ; surgery ; Heart-Lung Transplantation ; methods ; Humans ; Male ; Organ Preservation Solutions ; Potassium ; administration & dosage

Transient hyperkalmia following intravenous administration of succinylcholine chloride is well known in normal patients. Increase in serum potassium(K+) can be greater in disease state, such as burn, massive trauma, uremia, neuromuscular disease, and tetanus. In the present study, changes in serum potassium and sodium level in 20 control group and 20 patients with infections of varying severity were measured after administration of SCC. The following results were obtained. 1) In all infected patients, serum potassium concentration was increased, hile wonly 70% of the control group was increased. 2) Serum potassium levels after administration of succinylcholine chloride increased in the control group(average 0.40+/-0.9mEq/L) and in the infected group(average 0.68+/-0.15 mEq/L). 3) The paek elevation of serum potassium level was 5 min. after administration of succinylcholine chloride in both groups. 4) There was asignificantly increased serum potassium concentration(p<0.01) in the infected group compared to the control group. 5) Serum K was increased above 0.5mEq/L in serum potassium level regardless of duration of infection. 6) Serum sodium concentration after administration of succinylcholine chloride was slightly decreased in both groups, but statistically this was not significant(p>0.05).
Administration, Intravenous ; Burns ; Humans ; Neuromuscular Diseases ; Potassium* ; Sodium* ; Succinylcholine* ; Tetanus ; Uremia

Accidents ; Acute Lung Injury ; chemically induced ; Administration, Oral ; Humans ; Mediastinal Emphysema ; complications ; Potassium Permanganate ; toxicity

OBJECTIVETo assess the effect of perioperative glucose-insulin-potassium (GIK) infusions on the prognosis in patients undergoing coronary artery bypass grafting.

METHODSElectronic databases including Cochrane library (Issue 3, 2011), Pubmed, EMbase, Highwire, CBM and CNKI were searched. A meta-analysis of all randomized controlled trials (RCTs) comparing GIK with control in coronary artery bypass grafting was performed. Study selection and meta-analysis were conducted which according to the Cochrane Handbook for systematic reviews. Date were extracted from these trials by 3 reviewers independently and analyzed by RevMan5.0 software.

RESULTSA total of 9 RCTs including 1029 patients were assessed in this study. GIK infusion was associated with significantly fewer perioperative myocardial infarctions (RR = 0.59, 95%CI: 0.38 - 0.91, P = 0.02), less inotropic support requirement (RR = 0.44, 95%CI: 0.35 - 0.56, P < 0.01), and increase the incidence of postoperative atrial fibrillation (RR = 1.23, 95%CI: 1.05 - 1.43, P = 0.009).

CONCLUSIONSGIK significantly reduces myocardial injury and improves cardiac function in patients undergoing coronary artery bypass grafting, but also increases the incidence of postoperative atrial fibrillation.

Coronary Artery Bypass ; Glucose ; administration & dosage ; Humans ; Insulin ; administration & dosage ; Myocardial Infarction ; prevention & control ; Postoperative Period ; Potassium ; administration & dosage ; Prognosis ; Randomized Controlled Trials as Topic

OBJECTIVE: Morphologic features of the corpse of rabbits died of potassium intoxication were studied in order to elucidate an objective evidence for forensic determination of death caused by potassium intoxication. METHODS: Macroscopic, microscopic, and ultrastructural (by transmission electron microscopy) changes were observed in the heart, brain, and kidney of rabbits killed by intravenous push or continuous infusion at 100 drips per minute with 0.3% and 1% KCl, respectively. Normal rabbits without any treatment killed by bleeding were used as controls. RESULTS: Macroscopically, cardiac dilatation and congestion/stasis as well as ischemic and hypoxic changes in various organs were observed in rabbits died of potassium injection. Microscopically and ultrastructurally, there were destruction of the cardiac fibers with thickening, concentrating, or disappearing of the Z-line, constriction of the glomerular capillaries, enlargement of the Bowman capsule, thinning and fusion of foot processes, as well as apoptosis with phagocytosis in brain observed, particularly in the group infused with 1% KCl. CONCLUSION The morphologic changes observed in the heart and kidney appear to be characteristic, supporting death caused by potassium intoxication.
Animals ; Apoptosis ; Brain/pathology* ; Cadaver ; Capillaries/pathology* ; Forensic Pathology ; Injections, Intravenous/methods* ; Kidney Glomerulus/pathology* ; Male ; Myocardium/pathology* ; Phagocytosis ; Postmortem Changes ; Potassium/poisoning* ; Potassium Chloride/administration & dosage* ; Rabbits