No abstract available.
Postoperative Nausea and Vomiting*

No abstract available.
Postoperative Nausea and Vomiting*

No abstract available.
Postoperative Nausea and Vomiting*

No abstract available.
Postoperative Nausea and Vomiting*

No abstract available.
Ondansetron* ; Postoperative Nausea and Vomiting*

Postoperative nausea and vomiting (PONV) is a long-standing issue, not a new concept in anesthesiology. Despite many studies over the last several decades, PONV remains a significant problem due to its complex mechanism. This review presents a summary of the mechanism underlying the pathogenesis of PONV, focusing on preventive treatment, particularly the use of new drugs. In addition, we discuss the latest meta-analysis results regarding correct clinical use of classic drugs. I also summarize the latest trends of postdischarge nausea and vomiting and the pharmacogenetics, which is attracting a great deal of attention from other medical fields in PONV-related studies. Finally, we discuss the drawbacks of existing studies on PONV and suggest a focus for future investigations.
Anesthesiology ; Nausea ; Pharmacogenetics ; Postoperative Nausea and Vomiting* ; Vomiting

No Abstract available.
Anesthetics* ; Delirium* ; Postoperative Nausea and Vomiting*

Background: Compared to adult patients undergoing upper limb surgery who receive general endotracheal anesthesia (GETA), those who receive peripheral nerve block (PNB) have better postoperative outcomes. Objective: To compare postoperative outcomes of PNB and GETA for orthopedic upper limb surgery among pediatric patients. Design: Cohort study. Setting: Southern Philippines Medical Center, Davao City, from December 2015 to May 2016. Participants: 94 boys and girls, 3 to 18 years old, who received either PNB or GETA for orthopedic upper limb surgery. Main outcome measures: Postoperative pain by visual analogue scale (VAS), need for postoperative rescue opioid doses. Main results: Of the 94 patients in this study, 47 (50%) received PNB, and the rest received GETA prior to surgery. Patients in the two anesthesia groups were comparable at baseline. The PNB group had lower mean VAS scores compared to the GETA group both at the post-anesthesia care unit (0.70 ± 1.52 versus 4.15 ± 1.78; p<0.001) and at the Orthopedics Ward (0.45 ± 1.49 versus 4.13 ± 1.68; p<0.001). The proportion of patients given postoperative rescue opioid doses was significantly lower in the PNB group (6/47; 12.77%) than in the GETA group (21/47; 44.62%; p=0.0006). Conclusion Pediatric patients for orthopedic upper limb surgery who received PNB had less pain postoperatively and needed postoperative rescue opioid doses less frequently compared to those who received GETA.
Anesthesia, Conduction ; Postoperative Nausea and Vomiting

Humans ; Postoperative Nausea and Vomiting ; Research Design

Postoperative emesis is still a troublesome problem in patients undergoing general anesthesia. We compared the efficacy and safety of ondansetron, a selective antagonist of serotonin 5HT3 receptors, within the 24hours postoperative period. Forty patients between the ages of 12 and 75 and ASA class I-III, having general anesthesia, undergoing elective abdominal surgery (except gynecologic surgery) were assigned to one of two treatment groups according to uncontrolled parallel comparative study design. A standard anesthetic technique consisting of thiopental-atracurium for induction and N2O-Enflurane for maintenance of anesthesia was used. The data showed that intravenous ondansetron 4mg i.v. before induction was significantly more effective in preventing emesis (n=20, 85%) than placebo (n=20, 60%). Nausea severity scores were also significantly decreased from 1.5+/-0.6 (mean+/-SE) in placebo group to 0.30.1 in ondansetron group (p<0.05). All patients receiving of ondansetron 4mg intravenously tolerated their treatment well, without any special adverse events. Conclusion; Ondansetron(4mg) given intravenously before induction to prevent postoperative nausea and vomiting in patients undergoing elective abdominal surgery was effective and safe.
Anesthesia ; Anesthesia, General ; Humans ; Nausea ; Ondansetron* ; Postoperative Nausea and Vomiting* ; Postoperative Period ; Serotonin ; Vomiting