No abstract available.
Postoperative Nausea and Vomiting*

No abstract available.
Postoperative Nausea and Vomiting*

No abstract available.
Postoperative Nausea and Vomiting*

No abstract available.
Postoperative Nausea and Vomiting*

No abstract available.
Ondansetron* ; Postoperative Nausea and Vomiting*

Postoperative nausea and vomiting (PONV) is a long-standing issue, not a new concept in anesthesiology. Despite many studies over the last several decades, PONV remains a significant problem due to its complex mechanism. This review presents a summary of the mechanism underlying the pathogenesis of PONV, focusing on preventive treatment, particularly the use of new drugs. In addition, we discuss the latest meta-analysis results regarding correct clinical use of classic drugs. I also summarize the latest trends of postdischarge nausea and vomiting and the pharmacogenetics, which is attracting a great deal of attention from other medical fields in PONV-related studies. Finally, we discuss the drawbacks of existing studies on PONV and suggest a focus for future investigations.
Anesthesiology ; Nausea ; Pharmacogenetics ; Postoperative Nausea and Vomiting* ; Vomiting

No Abstract available.
Anesthetics* ; Delirium* ; Postoperative Nausea and Vomiting*

Background: Compared to adult patients undergoing upper limb surgery who receive general endotracheal anesthesia (GETA), those who receive peripheral nerve block (PNB) have better postoperative outcomes. Objective: To compare postoperative outcomes of PNB and GETA for orthopedic upper limb surgery among pediatric patients. Design: Cohort study. Setting: Southern Philippines Medical Center, Davao City, from December 2015 to May 2016. Participants: 94 boys and girls, 3 to 18 years old, who received either PNB or GETA for orthopedic upper limb surgery. Main outcome measures: Postoperative pain by visual analogue scale (VAS), need for postoperative rescue opioid doses. Main results: Of the 94 patients in this study, 47 (50%) received PNB, and the rest received GETA prior to surgery. Patients in the two anesthesia groups were comparable at baseline. The PNB group had lower mean VAS scores compared to the GETA group both at the post-anesthesia care unit (0.70 ± 1.52 versus 4.15 ± 1.78; p<0.001) and at the Orthopedics Ward (0.45 ± 1.49 versus 4.13 ± 1.68; p<0.001). The proportion of patients given postoperative rescue opioid doses was significantly lower in the PNB group (6/47; 12.77%) than in the GETA group (21/47; 44.62%; p=0.0006). Conclusion Pediatric patients for orthopedic upper limb surgery who received PNB had less pain postoperatively and needed postoperative rescue opioid doses less frequently compared to those who received GETA.
Anesthesia, Conduction ; Postoperative Nausea and Vomiting

Humans ; Postoperative Nausea and Vomiting ; Research Design

BACKGROUND: A prospective study was performed to evaluate the preventive effect of intravenous (IV) ondansetron on postoperative nausea and vomiting (PONV) due to epidural morphine for postoperative pain control after major abdominal surgery. METHODS: One hundred patients undergoing elective major abdominal surgery were randomly devided into two groups, group O (n = 50) receiving IV ondansetron and group C (n = 50) receiving IV saline. After bolus epidural morphine were injected to all patients thirty minutes before the end of surgery, group O received ondansetron 8 mg and group C received normal saline intravenously. Incidence and severity of nausea, episodes of vomiting, patient's satisfaction, side effects such as pruritus, headache, dizziness related to epidural morphine were checked at 6, 24 hours after operation. RESULTS: The incidence and severity of nausea were significantly decreased in group O than group C during the first 24 hours after surgery. There were no significant differences in postoperative pain scores and patient's satisfaction between groups. The patients who didn't experienced PONV were significantly more satisfied than those who experienced PONV after surgery. CONCLUSION: Ondansetron decrease the incidence and severity of nausea in patients receiving epidural morphine for postoperative pain control after major abdominal surgery.
Dizziness ; Headache ; Humans ; Incidence ; Morphine* ; Nausea ; Ondansetron* ; Pain, Postoperative ; Postoperative Nausea and Vomiting* ; Prospective Studies ; Pruritus ; Vomiting