1.Efficacy of Intravitreal Triamcinolone Acetonide for Eyes with Postvitrectomy Diabetic Vitreous Hemorrhage.
Sun Young LEE ; Hee Gyung LEE ; Hyewon CHUNG ; Young Hee YOON ; June Gone KIM
Korean Journal of Ophthalmology 2007;21(4):208-212
PURPOSE: To evaluate the efficacy of intravitreal triamcinolone acetonide (IVT) for the management of postvitrectomy diabetic vitreous hemorrhage. METHODS: The authors conducted a retrospective study of patients with postvitrectomy diabetic vitreous hemorrhage who were administered 4 mg (0.1 cc) of triamcinolone acetonide ophthalmic suspension. Ocular history, adverse events, BCVA, intraocular pressure, external eye examination, slit-lamp biomicroscopy, fundus examination, B-scan ultrasonography, and fundus photography were assessed on day 1, weeks 1, 2, and 4 and months 2 and 3. RESULTS: There were 19 eyes of 18 consecutive patients with mean follow-up after IVT injection of 28 weeks. Of the 19 eyes, 17 eyes (89%) experienced clearing of vitreous hemorrhage within 1 to 5 weeks (mean, 1.7 weeks) with visible triamcinolone precipitates along with blood clot in the inferior aspect of fundus. Of these 17 eyes, 12 eyes (63%) maintained vitreous hemorrhage-free condition at last follow-up with a mean visual acuity of 20/63 (range, 20/320 20/25), whereas 5 (29%) developed recurrent vitreous hemorrhage after clearing of vitreous hemorrhage. Vitreous hemorrhage was not cleared in 2 eyes, which required surgical procedures. CONCLUSIONS: IVT injection may be beneficial for clearing recurrent postvitrectomy Diabetic Vitreous Hemorrhage.
Adult
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Aged
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Diabetic Retinopathy/*complications/diagnosis
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Female
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Follow-Up Studies
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Glucocorticoids/*administration & dosage
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Humans
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Injections
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Male
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Microscopy, Acoustic
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Middle Aged
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Postoperative Hemorrhage/diagnosis/*drug therapy/etiology
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Retrospective Studies
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Time Factors
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Treatment Outcome
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Triamcinolone Acetonide/*administration & dosage
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Visual Acuity
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Vitrectomy/*adverse effects
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Vitreous Body
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Vitreous Hemorrhage/diagnosis/*drug therapy/etiology