Intraductal papillary mucinous neoplasm (IPMN) is a recently recognized clinicopathologic entity characterized by dilatation of pancreatic duct filled with copious mucin and papillary ductal epithelial proliferation ranging from simple hyperplasia to invasive carcinoma. The exact clinicopathologic identification of this tumor is important because of favorable prognosis contrast to that of conventional ductal adenocarcinoma. Herein we report a case of surgically resected typical IPMN. A 59-year-old man had a long history of diabetes mellitus with epigastric pain of 4 months duration. Ultrasonography and computed tomographic examination revealed cystic dilatations of main pancreatic duct in the head. The patient underwent total pancreatectomy. The gross appearance showed diffuse dilatation of main pancreatic duct associated with cystic dilatation of subbranches in the uncinate process. Histologic examination revealed diffuse papillary proliferations lined by mucinous epithelium with mild atypism within ectatic ducts. No invasive carcinoma was noted. Histochemically, the papillary epithelium contained mostly neutral and acid sialomucin.
Male ; Humans

The gastric polyps may be premalignant lesions and they should be removed as possible. The gastric polyps can be remoued by various endoscopic methods. The safety and therapeutic effectiveness of snare polypectomy, neodymium YAG laser therapy and electrocutery were compared in a total number of 106 patients who were diagnosed as benign polyps by means of endoscopic biopsy.Safety was evaluated by the rate of complications such as perforation and bleeding, and therapeutic effectiveness was evaluated by the average numbers of treatment session of each modality. Average numbers of treatment session of snare polypectomy, laser therapy and electrocautery were 1.04, 1.38 and l.44, respectively. Average numbers of treatment session of snare polypectomy were significantly (p<0.05) lower than those of other two methods. Perforation was not occurred in any group. Bleeding rates after snare polypectomy, laser therapy and electrocautery were 17.4%, 1.0% and 3.8%, respectively. Bleeding was significantly (p<0,05) more frequent after snare polypectomy than after other two methods. In conclusion therapeutic effectiveness was best in snare polypectomy but complication was most frequent after snare polypectomy. There was no difference between laser therapy and electrocautery for therapeutic effectiveness and safety. Therfore, laser therapy and electrocautery caa be used for the removal of flat adenoma, alternatively.
Adenoma ; Electrocoagulation ; Hemorrhage ; Humans ; Laser Therapy ; Lasers, Solid-State ; Neodymium ; Polyps ; SNARE Proteins

The gastric polyps may be premalignant lesions and they should be removed as possible. The gastric polyps can be remoued by various endoscopic methods. The safety and therapeutic effectiveness of snare polypectomy, neodymium YAG laser therapy and electrocutery were compared in a total number of 106 patients who were diagnosed as benign polyps by means of endoscopic biopsy.Safety was evaluated by the rate of complications such as perforation and bleeding, and therapeutic effectiveness was evaluated by the average numbers of treatment session of each modality. Average numbers of treatment session of snare polypectomy, laser therapy and electrocautery were 1.04, 1.38 and l.44, respectively. Average numbers of treatment session of snare polypectomy were significantly (p<0.05) lower than those of other two methods. Perforation was not occurred in any group. Bleeding rates after snare polypectomy, laser therapy and electrocautery were 17.4%, 1.0% and 3.8%, respectively. Bleeding was significantly (p<0,05) more frequent after snare polypectomy than after other two methods. In conclusion therapeutic effectiveness was best in snare polypectomy but complication was most frequent after snare polypectomy. There was no difference between laser therapy and electrocautery for therapeutic effectiveness and safety. Therfore, laser therapy and electrocautery caa be used for the removal of flat adenoma, alternatively.
Adenoma ; Electrocoagulation ; Hemorrhage ; Humans ; Laser Therapy ; Lasers, Solid-State ; Neodymium ; Polyps ; SNARE Proteins

The condition of an idiopathically dilated colon appears to be clinically heterogenous, very uncommon, and subsequently often poorly managed. Recently, one case of idiopathic megacolon presented by constipation was investigated. The patient was abruptly constipated 6 months prior to the hospital visit. The results of a barium enema and colonoscopy were nonspecific. On plain abdominal radiographs, the ascending and transverse colon were markedly dilated, and the descending colon was not visible. During the conservative management, which included laxative and prokinetic medication, the clinical symptoms and the colonic dilatations on plain radiographs were reduced, and discharged. After that however, repetitive admissions due to abdominal distension and constipation ensued, and therefore a total colectomy was performed in order to improve the patient's quality of life.
Barium ; Colectomy ; Colon ; Colon, Descending ; Colon, Transverse ; Colonoscopy ; Constipation* ; Dilatation ; Enema ; Humans ; Megacolon* ; Quality of Life

The condition of an idiopathically dilated colon appears to be clinically heterogenous, very uncommon, and subsequently often poorly managed. Recently, one case of idiopathic megacolon presented by constipation was investigated. The patient was abruptly constipated 6 months prior to the hospital visit. The results of a barium enema and colonoscopy were nonspecific. On plain abdominal radiographs, the ascending and transverse colon were markedly dilated, and the descending colon was not visible. During the conservative management, which included laxative and prokinetic medication, the clinical symptoms and the colonic dilatations on plain radiographs were reduced, and discharged. After that however, repetitive admissions due to abdominal distension and constipation ensued, and therefore a total colectomy was performed in order to improve the patient's quality of life.
Barium ; Colectomy ; Colon ; Colon, Descending ; Colon, Transverse ; Colonoscopy ; Constipation* ; Dilatation ; Enema ; Humans ; Megacolon* ; Quality of Life