1.A case of polymyositis associated with Hashimoto's thyroiditis.
Shi Jung SUNG ; Se Jin HWANG ; Jong Min KIM ; Young Am LEE ; Ji Seon OH ; Jae Hee SUH ; Seung Won CHOI
The Korean Journal of Internal Medicine 2013;28(3):380-382
No abstract available.
Female
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Hashimoto Disease/*complications/diagnosis
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Humans
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Polymyositis/*complications/diagnosis
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Young Adult
2.Hepatocellular Carcinoma, Polymyositis, Rhabdomyolysis, and Acute Renal Failure.
Mi Jeong KIM ; Jin A KIM ; Mi Sook SUNG ; Jun Ki MIN
Journal of Korean Medical Science 2004;19(6):891-894
A 55 yr-old man presented with progressive muscle weakness and oliguria for 5days. Laboratory findings suggested rhabdomyolysis complicated with acute renal failure. A diagnosis of polymyositis was based upon the proximal muscle weakness on both upper and lower limbs, elevated muscle enzyme levels, muscle biopsy findings and the needle electromyography findings. The muscle biopsy showed extensive muscle necrosis and calcification. Investigations for underlying malignancy demonstrated hepatocellular carcinoma. The patient was managed with hemodialysis and high dose prednisolone. His renal function was fully recovered and his muscle power did improve slightly, but he died of a rupture of the hepatic tumor. In our view, this is an interesting case in that the hepatocellular carcinoma was associated with polymyositis and fulminant rhabdomyolysis-induced acute renal failure requiring hemodialysis.
Carcinoma, Hepatocellular/complications/*diagnosis
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Diagnosis, Differential
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Humans
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Kidney Failure, Acute/*diagnosis/etiology
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Liver Neoplasms/complications/*diagnosis
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Male
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Middle Aged
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Polymyositis/complications/*diagnosis
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Rhabdomyolysis/*diagnosis/etiology
3.Complex repetitive discharge on electromyography as a risk factor for malignancy in idiopathic inflammatory myopathy.
Na Ri KIM ; Eon Jeong NAM ; Jong Wan KANG ; Hyun Seok SONG ; Churl Hyun IM ; Young Mo KANG
The Korean Journal of Internal Medicine 2014;29(6):814-821
BACKGROUND/AIMS: We investigated the electromyography (EMG) findings and demographic, clinical, and laboratory features that may predict the development of malignancy in patients with idiopathic inflammatory myopathy (IIM). METHODS: In total, 61 patients, 36 with dermatomyositis and 25 with polymyositis, were included. Patients were divided into those with and without malignancies, and comparisons were made between the groups in terms of their demographic, clinical, laboratory, and EMG findings. RESULTS: The frequencies of malignancies associated with dermatomyositis and polymyositis were 22% and 8%, respectively. Patients with malignancies showed a significantly higher incidence of dysphagia (odds ratio [OR], 21.50; 95% confidence interval [CI], 3.84 to 120.49), absence of interstitial lung disease (ILD; OR, 0.12; 95% CI, 0.01 to 0.98), and complex repetitive discharge (CRD) on the EMG (OR, 26.25; 95% CI, 2.67 to 258.52), versus those without. After adjustment for age, dysphagia and CRD remained significant, while ILD showed a trend for a difference but was not statistically significant. Multivariate analysis revealed that the CRD conferred an OR of 25.99 (95% CI, 1.27 to 531.86) for malignancy. When the frequency of malignancy was analyzed according to the number of risk factors, patients with three risk factors showed a significantly higher incidence of malignancy, versus those with fewer than two (p = 0.014). CONCLUSIONS: We demonstrated for the first time that CRD on the EMG was an additional independent risk factor for malignancy in IIM. Further studies on a larger scale are needed to confirm the importance of CRD as a risk factor for malignancy in IIM.
Action Potentials
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Adult
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Aged
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Dermatomyositis/complications/*diagnosis/physiopathology
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*Electromyography
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Female
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Humans
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Logistic Models
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Male
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Middle Aged
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Multivariate Analysis
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Muscle, Skeletal/*innervation/pathology
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Neoplasms/*etiology
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Odds Ratio
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Polymyositis/complications/*diagnosis/physiopathology
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Predictive Value of Tests
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Retrospective Studies
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Risk Factors
4.A Case of Pneumatosis Cystoids Intestinalis with Polymyositis.
Soon Jae LEE ; Ji Young PARK ; Se Ah KWON ; Dong Hee KOH ; Min Ho CHOI ; Hyun Ju JANG ; Sea Hyub KAE ; Jin LEE
The Korean Journal of Gastroenterology 2011;57(4):249-252
Pneumatosis cystoides intestinalis (PCI), characterized by presence of intramural gas cyst in the intestinal wall is associated with various medical condition. Polymyosistis, however, is rarely associated with PCI. Few cases are reported in the world, and none has not been reported previously in Korea. A 67-year-old woman with polymyositis developed mild abdominal pain and abdominal distension during treatment with steroid and azathioprine. Radiographic findings including CT scan showed intraperitoneal free gas and intramural air, compatible with PCI. The patient's symptom and clinical findings improved after the treatment with antibiotics and high-dose oxygen therapy.
Aged
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Anti-Bacterial Agents/therapeutic use
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Anti-Inflammatory Agents/therapeutic use
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Azathioprine/therapeutic use
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Cefotaxime/therapeutic use
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Female
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Humans
;
Oxygen Inhalation Therapy
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Pneumatosis Cystoides Intestinalis/complications/*diagnosis/drug therapy
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Polymyositis/complications/*diagnosis/drug therapy
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Prednisolone/therapeutic use
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Radiography, Abdominal
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Tomography, X-Ray Computed
5.A Case of Pneumatosis Cystoids Intestinalis with Polymyositis.
Soon Jae LEE ; Ji Young PARK ; Se Ah KWON ; Dong Hee KOH ; Min Ho CHOI ; Hyun Ju JANG ; Sea Hyub KAE ; Jin LEE
The Korean Journal of Gastroenterology 2011;57(4):249-252
Pneumatosis cystoides intestinalis (PCI), characterized by presence of intramural gas cyst in the intestinal wall is associated with various medical condition. Polymyosistis, however, is rarely associated with PCI. Few cases are reported in the world, and none has not been reported previously in Korea. A 67-year-old woman with polymyositis developed mild abdominal pain and abdominal distension during treatment with steroid and azathioprine. Radiographic findings including CT scan showed intraperitoneal free gas and intramural air, compatible with PCI. The patient's symptom and clinical findings improved after the treatment with antibiotics and high-dose oxygen therapy.
Aged
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Anti-Bacterial Agents/therapeutic use
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Anti-Inflammatory Agents/therapeutic use
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Azathioprine/therapeutic use
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Cefotaxime/therapeutic use
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Female
;
Humans
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Oxygen Inhalation Therapy
;
Pneumatosis Cystoides Intestinalis/complications/*diagnosis/drug therapy
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Polymyositis/complications/*diagnosis/drug therapy
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Prednisolone/therapeutic use
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Radiography, Abdominal
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Tomography, X-Ray Computed