1.The relation between chronic viral hepatitis and polymyositis.
Korean Journal of Medicine 1999;56(5):664-664
No abstract available.
Hepatitis*
;
Polymyositis*
2.A case of polymyositis associated with ascending colon cancer.
Seok Hwan LEE ; Kee Hyung LEE ; Joung Il LEE ; Ju Hie LEE
Journal of the Korean Society of Coloproctology 1992;8(3):303-310
No abstract available.
Colon, Ascending*
;
Polymyositis*
3.Anesthesia for flap surgery in a patient with polymyositis.
Sowoon AHN ; Ju Ho LEE ; Eun Ah YANG ; Chunghyun PARK ; Dong Wook SHIN
Korean Journal of Anesthesiology 2014;67(Suppl):S79-S80
No abstract available.
Anesthesia*
;
Humans
;
Polymyositis*
4.Polymyositis after Pegylated Interferon Therapy for Hepatitis C.
Shi Nae KIM ; Seung Min HAN ; Joong Hyun PARK ; Jeong Yeon KIM ; Jae Hyeon PARK
Journal of the Korean Neurological Association 2014;32(4):342-344
No abstract available.
Hepatitis C*
;
Interferons*
;
Polymyositis*
5.A case of polymyositis with myocardial involvement.
Shiyin ZHANG ; Yuyin LUO ; Qiyin SUN
Chinese Journal of Cardiology 2014;42(8):701-701
6.A Case of Eosinophilic Polymyositis in a Patient with IgA Nephropathy.
Korean Journal of Clinical Neurophysiology 2015;17(2):95-97
No abstract available.
Eosinophils*
;
Glomerulonephritis, IGA*
;
Humans
;
Immunoglobulin A*
;
Polymyositis*
8.Advances in epigenetic markers of dermatomyositis/polymyositis.
Yi Ying YANG ; Xiao Xia ZUO ; Hong Lin ZHU ; Si Jia LIU
Journal of Peking University(Health Sciences) 2019;51(2):374-377
Idiopathic inflammatory myopathy (IIM) is a rare group of autoimmune diseases, characterized by chronic muscle weakness, muscle fatigue and infiltration of single nuclear cells in skeletal muscle. Its subtypes include dermatomyositis (DM), polymyositis (PM), inclusion body myositis (IBM) and immune-mediated necrotizing myositis (IMNM), and the most common subtypes are DM and PM. PM is an autoimmune disease mainly manifested by muscle damage. When the skin is involved, it is called DM. The incidence of IIM was relatively low, which was 1.16-19 per million people/year, but the mortality was high and the prognosis was poor. The pathogenesis of IIM is still unclear. Previous studies suggest that both immune and non-immune mechanisms are involved in its pathogenesis, especially cellular and humoral immunity. In recent years, researchers have conducted a number of studies on the pathogenesis of IIM, especially in the study of DM/PM with the application of high-throughput biometrics. Epigenetics is a discipline that refers to the genetic phenomena of DNA methylation spectrum, chromatin structure state and gene expression spectrum transferred between cells without any changes in DNA sequence, including DNA methylation, chromatin modification and non-coding RNA changes. A large number of studies have shown that epigenetic modification plays an important role in many diseases, especially in cancer. Recent studies have also found a series of epigenetic markers related to the occurrence and development of DM/PM, mainly in the aspect of non-coding RNA changes, such as miR-10a, miR-206, etc. And there has also been some research on DNA methylation. However, no studies have been reported on whether chromatin modification is involved in the pathogenesis of DM/PM. The pathogenesis of DM/PM is complex and diverse. With the development of research, certain microRNAs (miRNAs) and long non-coding RNAs (lncRNAs) may become biological markers for the early diagnosis of DM/PM. Therefore, this paper mainly expounds the research progress of the biomarkers of DM/PM from the aspect of epigenetics.
Biomarkers
;
Dermatomyositis
;
Humans
;
MicroRNAs
;
Muscle, Skeletal
;
Polymyositis
9.The Expression of Toll-like Receptors in Idiopathic Inflammatory Myopathies.
Geun Tae KIM ; Jun Hee LEE ; Seung Hoon BAEK ; Joung Wook LEE ; Mi Ra CHO ; Ju In KIM ; Sun Hee LEE ; Dae Seong KIM ; Sung Il KIM
The Journal of the Korean Rheumatism Association 2007;14(2):118-124
Objective: To investigate the expression of toll-like receptor (TLR)-2, 4 and 9 in idiopathic inflammatory myopathies (IIMs). Methods: The expression of TLR-2, 4 and 9 was measured by real-time RT-PCR and immunohistochemical stain (IHS) from muscle tissues in patients with IIMs and controls. Results: The expression levels of TLR-2, 4 and 9 in IIMs were significantly higher than controls. TLR-2, 4 and 9 were mainly expressed on sarcolemma of muscle fibers, perimysial vascular endothelium and infiltrating inflammatory cells in dermatomyositis, whereas, they were mainly expressed on sarcolemma of muscle fibers, destructed muscle fibers, and enodmysial infiltrating inflammatory cells in polymyositis. Conclusion: TLR-2, 4 and 9 were highly expressed in muscle tissue of IIMs. These results suggest that TLR-2, 4 and 9 play a role in pathogenesis of IIMs.
Dermatomyositis
;
Endothelium, Vascular
;
Humans
;
Myositis*
;
Polymyositis
;
Sarcolemma
;
Toll-Like Receptors*
10.A Case of Atypical Polymyositis Diagnosed as Muscular Dystrophy on Muscle Biopsy.
Yun Joon KIM ; Tae Young CHO ; Il Nam SUNWOO ; Tae Seung KIM ; Sang Ahm LEE
Journal of the Korean Neurological Association 1992;10(4):566-569
Though the polymyositis, one of the common adult-onset myopathy, is treatable, the diverse clinical manifestation and course sometimes lead the clinician to incorrect diagnosis. Here we report a case of polymyositis, presented with atypical features and diagnosed as muscular dystrophy on muscle biopsy previously, but showed marked clinical improvement after combined treatment with prednisolone and methotrexate.
Biopsy*
;
Diagnosis
;
Methotrexate
;
Muscular Diseases
;
Muscular Dystrophies*
;
Polymyositis*
;
Prednisolone