The parameters of pH, albumin of the calf serum, which produced in Poliomyelitis Vaccine Research and Production Center, are higher than standard sample of Gibco Company. In general, the other parameters such as hemoglobin, protein, and bilirubin were lower than the standard sample. The viscidity of study samples is equivalent to standard sample. The optimum serum - supplemented concentration in the medium for cell culture is 10%. The viscidity clearly effect to the growth of the cells get from the medium for monkey kidney cell growth when add the calf serum- product of Polimyelitis vaccine research and production center is 82.16% in comparing with the standard sample.
serum ; vaccines ; diagnosis ; Poliomyelitis

The parameters of pH, albumin of the calf serum, which produced in Poliomyelitis Vaccine Research and Production Center, are higher than standard sample of Gibco Company. In general, the other parameters such as hemoglobin, protein, and bilirubin were lower than the standard sample. The viscidity of study samples is equivalent to standard sample. The optimum serum - supplemented concentration in the medium for cell culture is 10%. The viscidity clearly effect to the growth of the cells get from the medium for monkey kidney cell growth when add the calf serum- product of Polimyelitis vaccine research and production center is 82.16% in comparing with the standard sample.
serum ; vaccines ; diagnosis ; Poliomyelitis

Humans ; Poliomyelitis/diagnosis* ; Fractures, Bone ; Lower Extremity ; Spinal Cord Injuries/diagnosis*

A relationship between preceding acute paralytic poliomyelitis and the later development of motor neuron disease has only occasionally been suggested since it was first postulated by Charcot in 1875. The authors recently experienced a 20-year-old male who was considered to have postpoliomyelitis muscular atrophy. We report this case in view of its rarity and necessity of differential diagnosis from other neuromuscular disorders. Clinical presentation included slowly progressive muscle wasting of left thigh for 4 years, mild weakness of left arm and both thigh, intermittent fasciculation, and previous history of acute paralytic poliomyelitis. Electromyographic findings showed fibrillation potentials, positive sharp waves, fasciculations, giant motor unit potentials and reduced interference patterns. Muscle biopsy revealed scattered small angulated fibers, individual myofiber degeneration and mild inflammatory cell infiltration.
Arm ; Biopsy ; Diagnosis, Differential ; Fasciculation ; Humans ; Male ; Motor Neuron Disease ; Poliomyelitis ; Postpoliomyelitis Syndrome* ; Thigh ; Young Adult

Isolated coronal fracture of medial femoral condyle with intact lateral femoral condyle is extremely rare. A high index of suspicion is necessary for early diagnosis especially in cases of undisplaced fractures. Here we report a case of medial Hoffa fracture in a post-polio limb presenting as chronic pain. Management of such fractures in limbs affected by late sequelae of poliomyelitis is particularly problematic in view of osteoporosis and osseous hypoplasia. The fracture was approached through medial parapatellar arthrotomy and fixation was done with cannulated cancellous screws in anteroposterior direction. Union was achieved at 16 weeks.
Adult ; Chronic Pain ; diagnosis ; Diagnosis, Differential ; Female ; Femoral Fractures ; diagnosis ; surgery ; Fracture Fixation, Internal ; Humans ; Poliomyelitis ; complications

This report describes a case of acute flaccid paralysis after administration of oral polio vaccine (OPV). A 4 month-old male patient with the decreased movement of left lower extremity for 1 month was transferred to the Department of Pediatrics. He received OPV with DTaP at 2 months of age. Flaccid paralysis was detected 4 weeks after OPV immunization. Attempts to isolate Sabin-like viruses in the two stool and CSF samples failed because those specimens were collected more than 2 month after the onset of paralysis. Hypotonic monoparesis (GIV/V), hypotonia and atrophy on the left lower extremity, and ipsilateral claw foot persisted for more than 18 months, while we followed him with rehabilitation therapy. This is the first case of officially approved, recipient vaccine-associated paralytic poliomyelitis in Korea.
Poliovirus Vaccine, Oral/*adverse effects ; Poliomyelitis/*chemically induced/diagnosis/rehabilitation ; Paraplegia/*chemically induced/diagnosis/rehabilitation ; Male ; Infant ; Humans

Dermatomyositis (DM) is an idiopathic inflammatory myopathy, characterized by inflammation of the proximal skeletal muscles and typical skin manifestations, which results in symmetric muscle weakness. A 43-year-old man was presented with skin rash and left leg weakness, and he had a history of poliomyelitis. Initially, he was diagnosed as having post-polio syndrome (PPS) due to unilateral muscle weakness and a result of an the electromyography (EMG), which had shown patterns of PPS. After 4 months with conservative therapy for PPS, weakness of bilateral upper arms had developed and skin rashes on his entire body had aggravated and progressed. He was diagnosed as having dermatomyositis, based on elevated muscle enzyme levels, typical skin rashes, and typical EMG findings, which indicated muscle disease. When a patient with previous poliomyelitis has a newly developed muscle weakness or pain, we should consider various possible causes other than PPS.
Adult ; Arm ; Dermatomyositis* ; Diagnosis, Differential* ; Electromyography ; Exanthema ; Humans ; Inflammation ; Leg ; Muscle Weakness* ; Muscle, Skeletal ; Myositis ; Poliomyelitis* ; Postpoliomyelitis Syndrome* ; Skin Manifestations

The relative incidence of cerebral palsy has increased recently over that of poliomyelitis, due to the improvement in the social, medical, and economic status of our country. It is important to check the pathologic reflexes for diagnosis, treatment and prognosis of cerebral palsy. We studied 84 cerebral palsied patients, between 1 to 13 years old, who were treated at our Crippled Childrens Rehabilitation Center. The motor age and pathologic reflexes were checked, and pathologic reflexes were checked, and the relationship between pathologic reflexes and walking was compared. The following results were obtained. 1) With increasing of chronological age, there was a tendericy to increasing of motor age, but the mean motor age did not increase after 8 years in chronological age, and no more than to about 20 months. 2) With increasing of motor age, a tendency to decreasing of frequency of pathologic reflexes was shown. 3) The followings were the most important pathologic reflexes in non walking group: a) positive supporting reaction b) supine lying c) prone lying d) Moro reflex e) asymetrical tonic neck f) protective extensor thrust.
Cerebral Palsy ; Child ; Clinical Study ; Deception ; Diagnosis ; Humans ; Incidence ; Neck ; Poliomyelitis ; Prognosis ; Reflex ; Reflex, Startle ; Rehabilitation Centers ; Walking

A study was conducted to provide comprehensive information in epidemiological state of crippled schoolchildren in Chungnam area from November 23, 1979 to 19, 1980. In this study, two step survey was conducted upon whole primary, middle and high school, and subsequent selected 537 case in total 3,063 crippled children. The results obtained are as follows; 1. The prevalence rate of orthopedic defect children was 3.7 per 1,000 and dominant male as 6 : 4. 2. It was relatively high the school grade and prevalence rate more increased. Prevalence rate was highest in high school as 4.7 per 1,000, middle in middle school as 4.4 per 1,000 and lowest in primary school as 3.1 per 1,000. 3. The most predominant group was 15-19 age as 52.9 percent. 4. The most common job of their parent was agriculture as 52.9 percent and next job sales and service. Economic state of Cripple's parent have revealed no particular difference. 5. In a family, the most common incidence rate was first children in both sex and decreased by ordered sibling. 6. Poliomyelitis was the most common cause as 71.5 percent and next cerebral palsy 11.9 percent. 7. The most common affected sited was lower extremity (Right: 42.3%, Left: 35.5%) and next upper extremity. Right was more dominant as 55:45. 8. Intelligence was decreased in cerebral palsy predominantly than other cause of defect, including poliomyelitis. 9. For the treatment of their condition at onset of illness, crippled children was utilized private clinic and herb medicine, but was changed tendency of treatment as acupuncture and moxibustion after diagnosis of cause defect.
Acupuncture ; Agriculture ; Cerebral Palsy ; Child ; Chungcheongnam-do* ; Commerce ; Diagnosis ; Humans ; Incidence ; Intelligence ; Lower Extremity ; Male ; Moxibustion ; Orthopedics ; Parents ; Poliomyelitis ; Prevalence ; Siblings ; Upper Extremity