No abstract available.
Poliomyelitis*

The results of the basic immunization of 3 doses of oral poliomyelitis vaccines for infant and boost immunization of 2 doses of oral poliomyelitis vaccine during 1993-1997 have shown that the poliomyelitis was significant reduced from 152 cases in 1993 to no case in 1998. The last case of poliomyelitis occurred in Phu yen province in 19th January 1997. In 2000, the poliomyelitis was eradicated in Vietnam. However, in order to prevent from returning the disease
Poliomyelitis ; Achievement

Our study is aimed to access polio situation and the surveillance activities of AFP/polio cases in Northern Vietnam from 1992 to 1997. Results showed that due to the quality of the regular and sentinel surveillance improved and the polio vaccination coverage sustained (over 90% for several years), the morbidity of polio has been decreased. There were 146 confirmed cases and 35 wild polio cases in 1992 and up to 1997, there were only 3 confirmed polio cases, none of wild polio cases have been reported since 1994.
Poliomyelitis ; Epidemiology

Data were collected from the Enlarged Immunization Program and the Poliomyelitis Eradication Program (1992-1999), also including inquiry forms and guidelines for detecting, investigating, and processing by Epi-Info. Results shown the epidemic was spread in prevailing of rural population (79.3%), under 5 years old children accounted for 87.9% of cases of poliomyelitis. The outbreaks occurred all around the year with the peak on March, April, May and September, October. Wild virus of the type 1 plays the main role in 97.8% of cases
Poliomyelitis ; Epidemiology

No Abstract Available.
Humans ; Poliomyelitis*

A study was conducted to test the sterility of 416 final lots of OPV produced by POLIOVAC, Vietnam from 1994 to 2003 in thioglycolate and soybean casein digest media under the standard operating procedure. The study results showed that all the tested lots (461/461 = 100%) had met the requirements for sterility
Infertility ; Poliomyelitis ; Antigens, Bacterial

Non - RIMAPREC test carried on 14 single harvests of polyomyelitis vaccine type 3 produced in the year 2002 in Hanoi Centre of Sabin vaccine showed that no DNA mutant was detected. WHO criteria on safety were met
Poliomyelitis ; Vaccines ; standards

The parameters of pH, albumin of the calf serum, which produced in Poliomyelitis Vaccine Research and Production Center, are higher than standard sample of Gibco Company. In general, the other parameters such as hemoglobin, protein, and bilirubin were lower than the standard sample. The viscidity of study samples is equivalent to standard sample. The optimum serum - supplemented concentration in the medium for cell culture is 10%. The viscidity clearly effect to the growth of the cells get from the medium for monkey kidney cell growth when add the calf serum- product of Polimyelitis vaccine research and production center is 82.16% in comparing with the standard sample.
serum ; vaccines ; diagnosis ; Poliomyelitis

The parameters of pH, albumin of the calf serum, which produced in Poliomyelitis Vaccine Research and Production Center, are higher than standard sample of Gibco Company. In general, the other parameters such as hemoglobin, protein, and bilirubin were lower than the standard sample. The viscidity of study samples is equivalent to standard sample. The optimum serum - supplemented concentration in the medium for cell culture is 10%. The viscidity clearly effect to the growth of the cells get from the medium for monkey kidney cell growth when add the calf serum- product of Polimyelitis vaccine research and production center is 82.16% in comparing with the standard sample.
serum ; vaccines ; diagnosis ; Poliomyelitis

The aim of this study is to examine the antibody response in children who have been given oral poliomyelitis vaccine (OPV) produced by POLIOVAC Ha Noi. The study included 105 children under five years of age (32 in Ha Noi and 73 in Thanh Hoa). In Ha Noi children, the antibody response to each type and to all the three-poliovirus types was 100%. In Thanh Hoa children, the antibody response is poliovirus type 1 was 95.9%, to type 2: 93.1% to type 3: 93.1% and to all the 3 type 91.8%. Very high geometric mean titers against poliovirus type 1, 2 and 3 were evidenced
vaccines ; Pharmaceutical Preparations ; Poliomyelitis