The combinations of gel activated charcoal and sorbitol in rational proportion (product name: Antipois- Bachmai) were given for 91 patients with ingestion-induced poisoning as protocol of Bachmai Poison Control Center. 76 cases (83.5%) were admitted before 6 hours and 85 cases (93.4%) before 12 hours. 66 patients (72.5%) were given 1 dose, 93.4% were given less than 3 doses, and in 2 patients (2.2%), 6 doses have been used. Antipois-Bachmai was used conveniently. Deposit was not observed in gastric sonde, so this drug prevented from obstruction due to charcoal. Almost patients had charcoal loose stool within first 12 hours.
Poisoning ; therapy

Acute poisoning was more frequently in the Internal - Pediatric pathology. During the past 3 years (1996-1998), there were 392 acute intoxicated patients hospitalized at the Department of Reanimation and Emergency (13.23% of total patients treated at the department). The degree of toxicity in severe and fatal situations accounts for 36.03%. The Department of Reanimation - Emergency in Hai Ba Trung Hospital have applied many methods of intensive care such as isotonic solution perfusion 77.3%, stomach washing 50.51%, active charcoal drinking 36.73%, specific medicine drinking 32%, diuretic, supportive respiration, nausea provoking... Therapeutic results were high (complete recovery 89.8%), the average therapeutic day with acute poisoning was only 1.28 days. Mortality rate was higher in the later comers (especially late after 6 hours), insecticides have provoked high death rate (10%) and by opium poisoning (9.78%), then the rest percentages were by Gardenal, alcohol, Seduxen...
Poisoning ; therapy

Herbicides ; poisoning ; Humans ; Paraquat ; poisoning ; Poisoning ; therapy

Investigating 103 intoxicated patients admitted to our dep. Reanimation and Emergency from 1st Jan1998 to 31stNov 1999, we remarked almost were males, aged between 16-30 years. Main drugs using were opium or opium residue by intravenous use. The frequent symptoms of acute drug poisoning were miotic 100%, coma status 79.61%, respiratory arrest 66.99%, and bradycardia 41.75%. Positive HIV in 12 persons (11.56%). Narcotic poisoning was severe. Early, active, appropriate treatments rapidly eliminated poisoning status after 1-3 hours with the death rate of 6.8%.
Narcotics ; Poisoning ; therapy ; emergencies

20 patients hospitalized from 1998 to 2000 due to acute organophosphate poisoning were treated by intravenous infusion of PAM at dose of 0.25g - 1g per hour. The dosage of PAM was adjusted according to concentrations of serum cholinesterase tested every 12 hours. The results of study showed that the clinical status was significantly improved: in-hospital stay time was shorter, dose of atropine was lower, severe complications such as paralysis, respiratory failure were decreased in comparison to previous studies. Thus, the level of serum cholinesterase is correlated to poisoning severity and is good indicator for adjustment of PAM dosage in the management of acute organophosphate poisoning.
Poisoning ; therapy ; serum ; therapeutics

Child ; Humans ; Paraquat ; poisoning ; Poisoning ; therapy

Hemoperfusion ; Humans ; Paraquat ; poisoning ; Poisoning ; therapy

OBJECTIVETo discuss the effectiveness of severe and acute organophosphate poisoning (AOPP) treated with plasma exchange in China.

METHODSResearches about effectiveness of severe AOPP treated with plasma exchange were analyzed by Review Manager 4.2 and fixed effect model of meta-analysis method were used.

RESULTSSix trials including 433 patients were identified. Treatment group including 211 patients adopted traditional physician therapy plus plasma exchange, and control group including 222 patients received physician therapy only. The case-fatality rate of the treatment group was lower than the control one [RR=0.30, 95%CI (0.19-0.49), P<0.01].

CONCLUSIONPlasma exchange can improve the cure rate of severe AOPP.

Humans ; Poisoning ; prevention & control ; therapy ; Solvents ; poisoning

Aniline Compounds ; poisoning ; Humans ; Poisoning ; therapy