PURPOSE: To describe the characteristic HRCT appearance and to evaluate the usefulness of HRCT in patients with welders' pneumoconiosis. MATERIALS AND METHODS: Chest radiographs and high-resolution computed tomography(HRCT) of 45 shipyard welders(male : female=41 : 4 ; age : 36-58 years, mean 47.8) with an occupational history of 4-25(mean 15.8) years were evaluated. Small rounded opacities in chest radiographs were read accordingto the ILO standard films(1980). HRCT were evaluated with micronodules, ground-glass attenuation, and other findings. Serial HRCT scans of seven welders taken 27 months apart were also evalauted. Two of these were still working in that job ; five had not worked as welders for 1-6(mean 4.4) years. RESULTS: HRCT of welders' pneumoconiosis showed poorly marginated centrilobular branching or dot opacities of low attenuation(n=36, 80.0%)with variable profusion and extent and ground-glass attenuation(n=8, 17.8%). HRCT abnormalities were seen in 39 welders(86.7%). It was able to depict micronodules(n=13) and/or ground-glass attenuation(n=3) in 15(68.2%) of 22welders with normal chest radiograph. Serial HRCT revealed no changes in parenchymal abnormalities(n=6) andslightly decreased profusion of micronodules(n=1). There was no HRCT abnormality suggesting gross parenchymal fibrosis. CONCLUSION: HRCT is more sensitive than chest radiography in detecting parenchymal changes in welders' pneumoconiosis, with characteristic poorly-marginated centrilobular branching opacities or dots and ground-glass attenuation. These HRCT appearances may be helpful in differentiating welders' pneumoconiosis from other diffuse lung diseases.
Pneumoconiosis* ; Radiography ; Radiography, Thoracic ; Thorax

Early recognition of coalescence in pneumoconiotic lesions is important because such coalescence is associated with the respiratory symptoms and deterioration of lung function. This complicated form of pneumoconiosis also has worse prognosis than does simple pneumoconiosis. High resolution computerized tomography(HRCT) provides significant additional information on the stage of the pneumoconiosis because it easily detects coalescence of nodules and emphysema that may not be apparent on the simple radiograph. The Purpose of this study is to clarify the role of HRCT in detection of large opacity and the relationship of change between the coalescence of nodules or emphysema and lung function in dust exposed workers. 1. There was good correlation between the HRCT grade of pneumoconiosis and ILO category of profusion. 5(9.09%) in 55 study population had confluent nodule extending over two or more cuts on HRCT. HRCT could identify the pneumoconiotic nodules which was not found by simple radiography in 6 workers with category 0/0. 2. No significant difference was observed coalescence of nodules and emphysema by dust type. 3. There was no significant difference in pulmonary function according to ILO and HRCT classification. 4. HRCT could detect the significant reduction in FEV1, FEV1/FVC, PEER, FEF25, FEF50, and FEF75 and remarkable increase in RV and TLC in study persons with emphysema compared with non-emphysema group. 5. Emphysema was found more often in nodules-coalescence group than small opacity group by HRCT. We found that HRCT could easily detect areas of coalescence and complicated emphysema compared to plain chest X-ray. Also our data suggest that it is primarily the degree of emphysema rather than the degree of pneumoconiosis that determines the level of pulmonary function.
Classification ; Dust ; Emphysema ; Humans ; Lung ; Pneumoconiosis* ; Prognosis ; Radiography ; Thorax

No abstract available.
Coal* ; Humans ; Pneumoconiosis* ; Radiography, Thoracic* ; Smoke* ; Smoking* ; Thorax*

Humans ; Pneumoconiosis ; diagnostic imaging ; Radiography, Thoracic ; standards ; X-Ray Film

Humans ; Pneumoconiosis ; diagnostic imaging ; Radiographic Image Enhancement ; Radiography ; methods

Humans ; Lung ; Pneumoconiosis/diagnostic imaging* ; Radiography ; Tomography, X-Ray Computed

This study was performed to investigate associations between serum alpha(1)-antitrypsin(AAT) concentration and radiological categories of coal workers' pneumoconlosis(CWP), between AAT concentration and pulmonary complications such as tuberculosis and emphysema, and to study associations between AAT concentration and FEV(1.0)% in CWP patients, We classified 254 CWP patients in D Hospital into categories of small opacity profusion. And we selected 86 subjects by with or without emphysematous finding in each categories by proportional stratified sampling method. Semm AAT concentrations were quantkated by single radial immunodiffusion method, and the findings of chest radiographs were evaluated by radilogist. The results were as follows: 1. Serum AAT concentrations were not significantly different among groups of radiological categories of small opacities. 2. Complication of emphysema was associated with smoking habits sigmficantlyl(chi square=12.16, p<0,01). And AAT concentraLion was higher in smokers and ex-smokers than in non-smokers. Serum AAT concentration was significantly higher in the cases with emphysema than in the cdses without emphybema{p<0.01). 3. Serum AAT concentration of the group with active pulmonary tuberculosis was significantly higher than with inactive or without: pulmonary tuberculosis group(p<0.1). 4. Serum AAT concentration of the group with low FEV(1.0)% was significantly higher than with high or normal group(p<0.05).
Anthracosis ; Coal* ; Emphysema ; Humans ; Immunodiffusion ; Pneumoconiosis* ; Radiography, Thoracic ; Smoke ; Smoking ; Tuberculosis ; Tuberculosis, Pulmonary

Lead, iron, and zinc concentrations in whole blood were determined by atomic absorption spectrophotometry, using a simple one-step dilution procedure, which were measured in 3 groups, 98 officers unexposed to dust or to metal, 58 coal miners without pneumoconiosis, and 113 coal workers' pneumoconiosis (CWP) patients. The results were as follows; 1. The precisions (C. V.%) of lead, iron, and zinc in blood were 12.65+/-6.95%, 1.47+/-1.25% and 6.35+/-3.34%, respectively. 2. Lead and zinc in blood showed the log-normal distribution unlike iron in blood which showed normal distribution. 3. Lead, iron, and zinc concentrations in blood of 3 groups were follows. There was significant difference of concentration far zinc in blood by groups statistically. 4. The difference of lead, iron, and zinc concentrations in blood was not significant (p>0.05) by profusion on chest radiographs.
Coal* ; Dust ; Humans ; Iron* ; Methods ; Pneumoconiosis* ; Radiography, Thoracic ; Spectrophotometry, Atomic ; Zinc*

Forced vital capacities (FVC's) and forced expiratory volumes in one second (FEV1.0's) of 26 pneumoconiosis patients were checked at admission and were followed up for 10 months through hospitalization. FVC's and FEV1.0's were slightly improved in 10 months after admission. The improvement of FVC's was statistically significant. In the group of large opacities in chest radiographs, FVC's and FEV1.0's were lower than those values in small opacity group at admission but improved more progressively. Similar finding was noted in the group of emphysema; those values were lower at admission but improved more progressively than those of non-emphysema group.
Emphysema ; Forced Expiratory Volume* ; Hospitalization ; Humans ; Pneumoconiosis* ; Radiography, Thoracic ; Vital Capacity*

PURPOSE: To describe chest radiographic and CT findings of silicosis, and to compare their findings. MATERIALS AND METHODS: Ten coal miners and six stonemasons were included in this study. All were male and their mean age was 53.1. The mean duration of dust exposure was 15.2 years(range, 5-30 years) in coal miners and 25.3years(range, 15|35 years) in stonemasons. Chest radiographs(n=16), conventional CT scans(n=4), and high resolutionCT(HRCT) scans(n=13) were evaluated. Parenchymal abnormalities were interpreted on the basis of ILO standardfilms(1980) in chest radiographs and on the basis of CAP(College of American Pathologists, 1979) in CT(HRCT)films. RESULTS: Chest radiographs revealed large opacities(n=8), small opacities(n=6), and normal findings(n=2).Type r(n=4) and category 1/1(n=2) were most common for small opacities, while for large opacities, category B(n=4) and category c(n=4) were most common. These small and large opacities were located predominantly in the area of the upper and middle lung. Associated findings were emphysema(n=7), eggshell nodal calcifications(n=3), pneumothorax(n=3), C-P angle blunting(n=4), and pleural thickening(n=1). CT scans revealed micronodules(n=16), nodules(n=3), and progressive massive fibrosis(PMF, n=8). All these lesions were located in the upper and middlelungs, especially in the central portion of the posterior lung. PMF showed diffuse and homogenous(n=3) andpuntate(n=2) calcifications, cavitations(n=5), air bronchograms(n=3), and necrosis(n=1). Peripheral paracicatricalemphysema was associated with PMF(n=8). Other findings were pneumothorax(n=4), emphysema(n=10), hilar andmediastinal nodal enlargement(n=11), bronchial wall thick-enings(n=6), bronchiectasis(n=1), pleuralthickening(n=7), parenchymal fibrosis(n=1), and pulmonary tuberculosis(n=2). CONCLUSION: Small and large opacities in chest radiographs and micronodules, nodules, and PMFs in CT(HRCT) films were located predominately inthe upper and middle lungs, especially in the central portion of the posterior lung in CT films. CT was superiorto plain chest radiographs in the following ways : (1) in the early detection of small opacities, including subpleural micronodules, and in the precise evaluation of their concentration and topography ; (2) in the detection of cavitation or calcification within conglomerate large opacity lesions ; (3) in the detection of hilarand mediastinal nodal enlargements ; and (4) in quantitative assessment of the severity of emphysema.
Coal ; Dust ; Emphysema ; Humans ; Lung ; Male ; Pneumoconiosis ; Radiography, Thoracic ; Silicosis* ; Thorax ; Tomography, X-Ray Computed