No abstract available.
Diagnosis* ; Pituitary Neoplasms*

No abstract available.
Diagnosis* ; Pituitary Neoplasms*

The clinical manifestations, the endocrine examinations and imaging features (MRI) of 91 patients with pituitary adenomas who had undergone transsphenoidal microsurgery from 1/2001 to 6/2003 were analyzed. The patient population was 49.5% female and 50.5% male. Mean age was 40.4 years.71 patients (78%) experienced decreased visual acuity, 67 patients (73.6) experienced headache. The most frequent tumor type was clinically nonfunctioning adenoma (50%), followed by prolactin-secreting adenoma (34.1%), growth hormone-secreting adenoma (13.2%) and last adrenocorticotropin-secreting adenoma (7.7%). there were 86 macro adenomas (94.5%) and in 13 patients (14.3%) the tumor invaded cavernous sinus. mean height was 33.05 mm, length was 26.58mm and width was 29.71mm. Conclusions: Clinical manifestations of pituitary adenomas are the result of excess hormone secretion (acromegaly, hyperprolactinemia, hypercortisolism...) and to compression of the surrounding structures (headache, visual disturbance and ocular movement palsy). The endocrine examinations are very important for diagnosis and treatment. MRI is the first choice.
Pituitary Neoplasms ; Diagnosis

TSH-secreting pituitary adenomas are rare, but have been diagnosed more frequently as radiographic techniques and biochemical assays have improved. These tumors are less easily cured by surgery than are other types of pituitary adenoma because of the large size and invasive features that many attain during the delay to diagnosis. We report a case of TSH-secreting giant pituitary adenoma in which biochemical remission was achieved with surgery.
Diagnosis ; Pituitary Neoplasms*

Primary intrasellar schwannomas or neurilemmomas occur rarely and mimic pituitary adenoma, radiologically and clinically. The authors describe the 6th case of primary intrasellar schwannoma mimicking a nonfunctioning pituitary macroadenoma, clinically as well as radiologically. Light microscopically, the present case did not show the typical histology of conventional schwannoma and the confirmative diagnosis was made with the aid of immunohistochemistry and electron microscope. Here, we review the possible hypotheses for pathogenesis of sellar schwannomas on unusual locations.
Diagnosis ; Immunohistochemistry ; Neurilemmoma* ; Pituitary Neoplasms

The authors present two cases of intrasellar schwannoma, a condition rarely reported in the literature. The patients presented with symptoms of hypopituitarism. Sellar magnetic resonance imaging(MRI) revealed intrasellar masses extending into the suprasellar region, with the normal pituitary gland also identifiable in the imaging study. The tumors were removed via trans-sphenoidal route, and found to be very firm, unlike usual pituitary adenomas. Tissue diagnosis confirmed the tumors as schwannoma.
Diagnosis ; Humans ; Hypopituitarism ; Neurilemmoma* ; Pituitary Gland ; Pituitary Neoplasms

Encephaloceles are known as rare craniofacial developmental anomalies which are herniation of cranial contents through a skull defect. Sphenoidal meningoencephalocele represents an important cause of reVersible visual loss. We report a rare case of pituitary adenoma accompanying sphenoidal meningoencephalocele with clival extension. Although the definitive diagnosis of cystic lesions in the sellar region before surgery is difficult, accurate diagnosis of these lesions is important to determine the type of treatment and predict prognostic outcome.
Craniofacial Abnormalities ; Diagnosis ; Encephalocele ; Pituitary Neoplasms* ; Skull

Encephaloceles are known as rare craniofacial developmental anomalies which are herniation of cranial contents through a skull defect. Sphenoidal meningoencephalocele represents an important cause of reVersible visual loss. We report a rare case of pituitary adenoma accompanying sphenoidal meningoencephalocele with clival extension. Although the definitive diagnosis of cystic lesions in the sellar region before surgery is difficult, accurate diagnosis of these lesions is important to determine the type of treatment and predict prognostic outcome.
Craniofacial Abnormalities ; Diagnosis ; Encephalocele ; Pituitary Neoplasms* ; Skull

The inflammatory lesion of the pituitary gland is unusual. A 33-year-old woman with headache, visual impairment, and menelipsis was admitted to the Second Xiangya Hospital, Central South University. The results of magnetic resonance imaging (MRI) for pituitary gland showed a sellar mass with iso-intensity on T1 weighted imaging and high signal on T2 weighted imaging. The homogeneous lesion was enhanced on contrast MRI. The pituitary stalk was thickened accompanied by the cavernous sinus invasion, which showed a "triangle" saddle occupation on the MRI coronal plane. An endocrinological examination revealed mild hypocortisolism. Th e patient was diagnosed as pituitary adenoma based on the MRI findings and endocrinological examination. Trans-sphenoidal surgery was performed. The intra-operative histological examination also suggested a pituitary adenoma. Th e histopathological examination showed accumulation of foamy cells and xanthomatous epithelioid cells, supporting the diagnosis of xanthomatous hypophysitis. Xanthomatous hypophysitis possesses certain MRI features. Th e most typical imaging features are the thickening of the pituitary stalk and the sign of "triangle" occupation on MRI coronal plane, which are very helpful to the correct diagnosis and optimal management.
Adenoma ; diagnosis ; Adult ; Female ; Humans ; Magnetic Resonance Imaging ; Pituitary Diseases ; diagnosis ; Pituitary Gland ; pathology ; Pituitary Neoplasms ; diagnosis

Diabetes Insipidus, Neurogenic ; diagnosis ; metabolism ; Humans ; Pituitary Neoplasms ; diagnosis ; secondary