1.Mathematical Model for Acousto-Optical Tomography and Its Numerical Simulation.
Haewon NAM ; Jangyong HUR ; Soyoung KIM ; Rena LEE
Korean Journal of Medical Physics 2012;23(1):42-47
In this paper, Acousto-Optical tomography is modeled by a linear integral equation and an inverse problem involving a diffusion equation in n-spatial dimensions. We make two-step mathematical model. First, we solve a linear integral equation. Assuming the optical energy fluence rate has been recovered from the previous equation, the absorption coefficient micro is then reconstructed by solving an inverse problem. Numerical experiments are presented for the case n=2. The traditional gradient descent method is used for the numerical simulations. The result of the gradient descent method produces the blurring effect. To get rid of the blurring effect, we suggest the total variation regularization for the minimization problem.
Absorption
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Diffusion
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Drug Combinations
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Models, Theoretical
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Piperonyl Butoxide
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Pyrethrins
2.A case of Systemic Toxicity that Occurred in an Adult Who Intentionally Ingested Rhododendron Sclippenbashii.
Sang Min JEONG ; Seung Han LEE ; Jeong Soo LIM ; Sang Yeol YOON ; Seung RYU ; Jin Woong LEE ; Seung Whan KIM ; In Sool YOO ; Yeon Ho YOU
Journal of The Korean Society of Clinical Toxicology 2009;7(2):180-182
It is well known that Rhododendron sclippenbashii contains the toxic material grayanotoxin. So, Koreans do not eat it, but they do eat azalea although it contains grayanotoxin. That is why there have been no reports about Rhododendron sclippenbashii intoxication after ingesting it intentionally, not accidentally. In this case, the patient was admitted to the emergency room with several toxic symptoms after intentionally consuming 50 blossoms of Rhododendron sclippenbashii to get rid of thirst. Treatment with saline infusion and atropine was successful and the outcome was favorable enough in this case to produce a complete cure without any sequelae at discharge. But toxic symptoms were seen for 24 hours, although the symptoms usually fade in 9 hours. Therefore, we should carefully treat and observe, for over 24 hours, the patient who intentionally ingests about 50 blossoms of Rhododendron sclippenbashii.
Adult
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Atropine
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Bradycardia
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Drug Combinations
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Emergencies
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Flowers
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Humans
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Intention
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Piperonyl Butoxide
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Pyrethrins
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Rhododendron
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Thirst
3.Experience with Various Scars after Treatment of Axillary Osmidrosis.
Journal of the Korean Society of Aesthetic Plastic Surgery 2008;14(2):150-155
The goal of osmidrosis operation is not only to be free from odor, but also to leave a minimal operation scar. In practice, however, many patients suffer from unfavorable axillary operation scars. Therefore, we herein report various postoperative axillary scars which we experienced. From January 1991 to December 2006, a total of 270 patients(74 men and 196 women) whose axillary osmidrosis had been treated by various methods more than once were included. We observed pre-existing operation scars of recurred patients who wanted revisional operation. Among the total patients, 118 patients had been treated once, 138 patients less than 5 times, and 14 patients more than 5 times. Previous treatment methods included excision in 216 cases, laser in 188 cases, subdermal excision in 63 cases, ultrasonic liposuction in 25 cases, Kobayashi insulated needles in 29 cases, and botulinum toxin injection in 1 case. We observed irregular scar, wide spread scar, hypertrophic scar, postburn scar, depressed scar, and pigmented scar. Pre-existing operation scars were not improved enough by revisional operation. We propose that it is important to select a proper method to effectively get rid of an axillary odor, leaving a minimal operation scar, because axillary area is not optimal for scar revision.
Botulinum Toxins
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Cicatrix
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Cicatrix, Hypertrophic
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Drug Combinations
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Humans
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Lipectomy
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Male
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Needles
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Odors
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Piperonyl Butoxide
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Pyrethrins
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Ultrasonics
4.Delayed Rupture of Flexor Pollicis Longus by Plate for Fracture of the Distal Radius.
So Min HWANG ; Sung Min AHN ; Kyoung Seok OH ; Jin Hyeong KIM ; Jun Ho LEE
Journal of the Korean Society of Plastic and Reconstructive Surgeons 2008;35(6):751-754
PURPOSE: Delayed rupture of flexor pollicis longus as a sequelae of the plate inserted for distal radius fracture is a very rare. This is the first case reported and published in Korea. METHODS: A 48 years old female patient visited hospital, complaining flexor disturbance of interphalangeal joint of left thumb, which suddenly occurred without any external wound. We found that she had received operation of fixing plate for fracture of left distal radius 10 years ago. As operational opinion, we have checked that flexor pollicis longus tendon has been ruptured with oblique ways being stimulated by extended plate to palmar side over long period. RESULTS: Authors performed tenorrhaphy of flexor pollicis longus without tendon graft and presented a successful active flexion of the left thumb interphalangeal joint 1 year after the operation. CONCLUSION: If the extruded part of the end plate is observed during the operation or follow-up, it is considered to be necessary to get rid of the plate as early as possible after the fracture healing.
Drug Combinations
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Female
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Follow-Up Studies
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Humans
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Joints
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Piperonyl Butoxide
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Pyrethrins
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Radius
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Radius Fractures
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Rupture
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Tendons
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Thumb
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Transplants
5.Updates in Psychotropic Medication for Lactating Women.
Su Young LEE ; Weonjeong LIM ; Ho Suk SUH ; Jong Hyun JEONG
Korean Journal of Psychopharmacology 2013;24(3):115-123
The use of psychotropic medications in lactating women is controversial. Despite widely accepted advantages of human milk, patients and professionals hesitate to use medications during breastfeeding. Package inserts written by manufacturers routinely discourage breastfeeding to prevent law suits. Here we conducted a review to help professionals to decide medication for lactating women on an evidence-based risk-benefit analysis. First, we reviewed lactational pharmacology. The relative infant dose (RID) was defined to give an objective measure for infant exposure to medication, and drugs with RID lesser than 10% were considered quite safe. Subsequently, we reviewed each category of psychotropic medications which were commonly used in mental illness. We provided information for each drug such as Dr. Hale's lactation risk category, RID, half-life, and time to peak plasma level as references for the risk analysis. There was no contraindicated psychotropic medication during breastfeeding, but for lithium, close monitoring of infant serum levels is warranted. In conclusion, most of medications used to treat mental illness in lactating women were usually safe. Nevertheless, medication use in lactating women should always be considered on an individualized risk-benefit analysis, and untoward adverse effects on the infant should be monitored.
Breast Feeding
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Drug Combinations
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Female
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Half-Life
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Humans
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Infant
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Jurisprudence
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Lactation
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Lithium
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Milk, Human
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Piperonyl Butoxide
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Plasma
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Product Labeling
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Pyrethrins
6.Reconsideration of treatment protocol on the reduction of Enterococcus faecalis associated with failed root canal treatment.
Woo Cheol LEE ; Seong Tae HONG ; Wonjun SHON
Journal of Korean Academy of Conservative Dentistry 2008;33(6):560-569
Microorganism survived in the root canal after root canal cleaning and shaping procedure is a main cause of root canal treatment failure. There are several mechanisms for the bacteria to survive in the root canal after chemomechanical preparation and root canal irrigation. Bacteria organized as biofilm has been suggested as an etiology of persistent periapical lesion. Recent studies were focus on removal of Enterococcus faecalis biofilm due to the report that the persistence of this bacteria after root canal treatment may be associated with its ability to form biofilm. Several investigations demonstrated that current root canal treatment protocol including use of NaOCl, EDTA and Chlorhexidine as irrigants is quite effective in eliminating E. faecalis biofilm. However, this microorganism still can survive in inaccessible areas of root canal system and evade host immune response, suppress immune activity and produce biofilm. Up to date, there is no possible clinical method to completely get rid of bacteria from the root canal. Once the root canal treatment failure occurred, and conventional treatment incorporating current therapeutic protocol has failed, periapical surgery or extraction should be considered rather than prolong the ineffected retreatment procedure.
Bacteria
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Biofilms
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Chlorhexidine
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Clinical Protocols
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Dental Pulp Cavity
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Drug Combinations
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Edetic Acid
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Enterococcus
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Enterococcus faecalis
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Piperonyl Butoxide
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Pyrethrins
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Retreatment
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Treatment Failure