Objective To investigate the effects of nursing intervention on self-management ability and quality of life of patients with chronic hepatitis B in antiviral treatment. Methods A total of 160 patients with chronic hepatitis B antiviral treatment were randomly divided into control group and observation group on average. The patients of control group were given routine care based on their own condition, while the patients of intervention group were assessed their self-management ability and quality of life by the self-management scale and quality of life evaluation questionnaire, and they were given specific nursing intervention based on the analysis of assessment, and then completed one year follow-up after discharge. Results The self-management ability of patients in the intervention group was higher than that of control group, while quality of life score in the intervention group was (66.43 ±5.94) compared (62.45 ±6.89) in the control group (t=2.48,P<0.05). Conclusions Nursing intervention can improve patients′self-management ability as well as quality of life.

Objective To investigate the application effects of bedside billing integration based on human factors integration theory in hospitalized patients.Methods Selected 322 patients from November 2012 to February 2016 the department of our hospital,according to the hospital bedside settlement time they were divided into observation group (March 2014-February 2016,settle account at bedside)and control group (November 2012-February 2014,settle account regularly),and the effects of nursing management,discharge waiting time,nurse′s satisfaction and patient′s satisfaction were compared.Results In observation group, nurse-patient relationship,nursing responsibility,and up-to-date hospital information were significantly better than that of control group;however,the discharge waiting time was significantly lower than that of control group (P <0.05 ).In 37 nurses,the work environment satisfaction,level of business satisfaction,interpersonal satisfaction,and nursing error rate were 91.89%,86.49%,89.19%,0.00% in observation group,while in 46 nurses of control group,they were 76.09%,76.09%,67.39%,4.35%.A total of 162 patients in observation group,discharged flow satisfaction,satisfaction with the quality of care,care attitude satisfaction and complaint rates were 98.15%,93.83%,91.98%,0.00%,they were 88.13%,81.88%,78.13%, 2.50% in 160 patients of control group.Conclusions Bedside billing integration based on human factors theory can obviously improve nurse′s and patient′s satisfaction,shorten the hospital waiting times,optimize discharge processes,so it is worthy of promotion.

ObjectiveTo study the effects of quality control circle (QCC) activities on improving the revisiting rate in discharged patients with chronic hepatitis B,so as to supervise patients to return visit regularly and improve medical compliance.Methods To investigate the revisiting situation of chronic hepatitis B patients discharged from infection department from January to March 2016 through QCC activities,in which the causes of the missing revisits were analyzed,and goals for improvement and corresponding measurements were set up. Corresponding measures were taken from April to October,2016. Statistical analysis was made to compare the revisiting rate before and after QCC activities.Results After taken the measures,the revisiting rate of discharged chronic hepatitis B patients was raised from 30.56% to 63.22%.Conclusions QCC activity can improve the revisiting rate and satisfaction of discharged patients with chronic hepatitis B.

Objective To explore the effects of self-management education on sharp instruments operation behavior of nursing staff. Methods Form January to June 2017, 231 nurses were given the self-management education on sharp instruments operation. The general self-efficacy, the self-management ability and the accuracy of sharp instruments operation behavior of nurses were compared before and after the education. Results After the self-management education, the general self-efficacy, the total score of self-management ability in sharp instruments operation, the control operation, the emotion management, the operation information management, occupational health management, the operation environment management and the accuracy of sharp instruments operation behavior of nurses also improved apparently than before, and the differences were statistically significant (P< 0.05). Conclusions The self-management education can improve the self-management ability and the accuracy of sharp instruments operation behavior of nurses.

Objective To explore the demands of health education on artificial liver support in chronic liver failure patients, and to discuss the appropriate methods of health education, in order to provide the basis for the health education of chronic liver failure patients with artificial liver support. Methods A total of 60 in-patients with artificial liver support from January 2012 to January 2013 were tested by questionnaires, from different aspects such as physical need, safety need, informational communication, emotional support, self-esteem and self-actualization, using multiple methods of one-on-one tutoring, multimedia, health brochures, lectures and bulletin boards, in order to investigate their demands of health education. Results Chronic liver failure patients with artificial liver support had demands on health education in many ways. The demand of different content and methods of health education, emotional support and one-on-one tutoring were the most. Patients with college degree or above needed health brochures more than patients with secondary education. Conclusions Chronic liver failure patients with artificial liver support have demands of health education in many ways, and patients with different educational levels have different demands. We should apply specific health education according to the different features of patients, in order to make patients cooperate and assure the treatment of artificial liver support to enhance the patients′recovery.

Objective To explore the effects of self-management intervention on medical waste disposal for patients with viral hepatitis at home.Methods Totally 116 patients with infectious hepatitis who used home injection were selected and divided into the control group (n=54) and the observation group (n=62) according to the order of admission. Patients in the control group were given routine education, while patients in the ob-servation group were given self-management intervention on the basis of routine education. Patients' knowledge about medical waste and self-management status about medical waste disposal in two groups were compared. Results Three months after intervention, the awareness rate of patients on medical waste in the observation group was (13.21±5.31) point and (7.52±3.80) point in the control group (t=6.547,P<0.01). The self-man-agement of medical waste disposal in the observation group was better than that of the control group (χ2=6.640, P<0.01).Conclusions Self management intervention is helpful in improving the standard of medical waste disposal in patients with viral hepatitis at home.

Objective:To explore the relationship between hematocrit, early fluid therapy, and clinical outcomes in patients with septic shock, and to provide evidence for fluid resuscitation therapy and prognosis assessment in these patients.Methods:The clinical information of patients with septic shock who were diagnosed and treated in the Emergency Intensive Care Unit (EICU) of the First Affiliated Hospital of Wenzhou Medical University from January 1, 2018 to December 31, 2020 were collected. Taking the survival or death of patients 28 days after admission as the end point of clinical research, the patients were divided into the survival and death groups. After analyzing the basic data of the two groups, the univariate and multivariate COX regression analyses were used to analyze the evaluation value of Δ Hematocrit (HCT) d2-d1 and ΔHCT d3-d1 on the prognosis of patients with septic shock. At the same time, the Kaplan-Meier survival curve was used to analyze the overall survival rate of patients with septic shock, and the smooth curve fitting graph was used to verify its relationship with net fluid intake and death. Results:There were 241 cases in the survival group and 67 cases in the death group. Univariate COX analysis showed statistically significant differences between the survival and death groups in acute physiology and chronic health evaluation Ⅱ (APACHE Ⅱ) ( P=0.0006), red cell volume distribution width (RDW) ( P=0.0043), age ( P=0.0184), ΔHCT d2-d1 ( P=0.0136), ΔHCT d3-d1 ( P=0.0204), and white blood cell (WBC) ( P=0.0444). Multivariate COX analysis showed that ΔHCT d2-d1 ( P=0.0115) and ΔHCT d3-d1 ( P=0.0029) were independent risk factors for death in EICU patients with septic shock. ΔHCT d2-d1 and ΔHCT d3-d1 were divided into three groups according to the three-digit method. The Kaplan-Meier survival curve showed no significant difference among the three groups in the overall survival rate related to ΔHCT d2-d1 ( P=0.16), but there was a statistically significant difference in the overall survival rate among the three groups related to ΔHCT d3-d1 ( P=0.025). The smooth fitting curve of ΔHCT d3-d1, net fluid intake, and prognosis showed that ΔHCT d3-d1 was negatively correlated with net fluid intake, and the middle ΔHCT d3-d1 group had the best prognosis. Conclusions:The value of ΔHCT d3-d1 is related to the net fluid intake of patients with septic shock. An appropriate decrease in HCT on the third day can improve the prognosis of patients with septic shock. The dynamic changes of hematocrit can provide a certain basis for fluid resuscitation and prognosis evaluation in patients with septic shock.

Objective:To explore the effects of "5-moment method" on antivirus medication compliance and revisit rate among patients with chronic hepatitis B.Methods:From January 2019 to June 2019, this study selected 120 chronic hepatitis B patients with antivirus therapy in the First Affiliated Hospital of Wenzhou Medical University as subjects by convenience sampling. All patients were divided into control group and observation group according to wards, 60 cases in each group. Control group carried out the traditional intervention including the routine medication education, hepatitis B information push by WeChat and discharged telephone follow-up. Observation group implemented the "5-moment" intervention involving the "5-moment" medication education, guiding patients to actively participate the safe and antiviral self-management through "5-moment" medication knowledge, applying "5-moment method" medication management in family medication management by informationization continuing service. This study compared the medication knowledge and compliance of patients with the self-designed Chronic Hepatitis B Antivirus Medication Knowledge Questionnaire and Morisky Medication Adherence Scale-8 (MMAS-8) as well as the revisit rate between two groups. There were 4 cases loss to follow-up in control group and no case loss to follow-up in observation group. A total of 116 subjects were included.Results:The awareness rate of antivirus medication knowledge and score of MMAS-8 of patients in observation group 6 months after intervention were (76.79±6.57) % and (7.17±0.78) respectively higher than those in control group with statistical differences ( t=19.883, 4.382; P<0.01) . The revisit rates of observation group and control group 6 months after intervention were 88.33% (53/60) and 55.36% (31/56) respectively with a statistical difference (χ 2=15.768, P<0.01) . Conclusions:The "5-moment method" can effectively improve the cognition of chronic hepatitis B patients on antivirus therapy, antivirus medication compliance of patients and revisit rate which is worthy of popularization in antivirus therapy management.