1.Dermoid cyst in the floor of the mouth with tongue fistula: a case report.
Pingfan WU ; Zhenge LEI ; Jian WU ; Linlin CHEN
West China Journal of Stomatology 2015;33(6):663-664
Dermoid cysts in the floor of the mouth with tongue fistula are unusual lesions. This study reported a case of dermoid cyst in the floor of the mouth with tongue fistula, analyzed the causes of such formation, and discussed the appropriate diagnosis and treatment methods by reviewing relevant literature.
Dermoid Cyst
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complications
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diagnosis
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therapy
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Fistula
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complications
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Humans
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Mouth Floor
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Mouth Neoplasms
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complications
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diagnosis
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therapy
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Tongue
2.Effect of glucagon like peptide-1 on HSP70 expression of rabbit thoracic aortic endothelial cells under the influence of high glucose level
Fanggang CAI ; Pingfan GUO ; Jie WU ; Tenghui ZHAN
Chinese Journal of General Surgery 2016;31(8):632-635
Objective To observe the effect of GLP-1 on HSP70 expression of rabbit thoracic aortic endothelial cells at high glucose level.Methods Rabbit thoracic aortic endothelial cells were isolated and cultured.Tunnel was used to assay endothelial cells apoptosis.Cell proliferation was analyzed with BUDR.The protein level of HSP70 were detected by Western blot.Results The proliferation of rabbit thoracic aortic endothelial cells cultured under high glucose (33 mmol/L) decreased,(0.54 ±0.06 vs 0.78 ±0.04,P < 0.01).The apoptosis and the protein level of HSP70 increased,(36.43% ± 6.85% vs 5.25% ±0.73%) and (0.94 ± 0.11 vs 0.29 ± 0.03,all P < 0.01).The proliferation of rabbit thoracic aortic endothelial cells (0.62 ± 0.06)in the GLP-1 group increased,the apoptosis ratio (10.13% ± 1.19%) and HSP70 expression (0.76 ± 0.05) decreased significantly (P < 0.05) compared with high glucose group.Conclusion GLP-1 can ameliorate high-glucose-induced rabbit thoracic aortic endothelial cells apoptosis and promote cell proliferation,attenuating high-glucose-induced level of HSP70 expression through the GLP-1 R-dependent pathways.
3.Clinical application of endoscope on removal of broken root from maxillary sinus.
Pingfan WU ; Lingyan GUO ; Linlin CHEN
West China Journal of Stomatology 2011;29(6):663-664
The broken root dislocated into the maxillary sinus is a common complication during the teeth extraction. This article reported broken roots of four patients dislocated into maxillary sinus were removed successfully by endoscope under local anesthesia through windowing in inferior nasal meatus. It is an efficient method, which has less wounds and shorter surgical time.
Endoscopes
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Humans
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Maxillary Sinus
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Tooth Extraction
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Tooth Root
4.Ectopic recurrence of ameloblastoma in the bucca region of the mandible: a case report.
Pingfan WU ; Qiang ZHANG ; Weibing TAN ; Linlin CHEN
West China Journal of Stomatology 2013;31(5):533-535
The postoperative recurrence of ameloblastoma is common. However, ectopic recurrence in clinical operations is rare. A case of ectopic recurrence of ameloblastoma in the bucca region of the mandible after 15 years is presented in this paper. The causes of the ectopic recurrence were analyzed based on relevant literature.
Ameloblastoma
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Cheek
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Choristoma
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Humans
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Mandible
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Mandibular Neoplasms
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Neoplasm Recurrence, Local
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Postoperative Period
5.Application of upper sternal mini-incision with debranching technique in Stanford B aortic dissection involving the arch
Gang WU ; Xiaoqing YAN ; Li ZHANG ; Xia GAO ; Changbo XIAO ; Yuxin CHEN ; Xianghui ZHANG ; Cong CUI ; Yafei ZHANG ; Kexiong SUN ; Pingfan WANG
Chinese Journal of Thoracic and Cardiovascular Surgery 2021;37(4):220-223
Objective:To investigate the safety and early and mid-term efficacy of upper sternal mini-incision with debranching technique in B aortic dissection involving the arch.Methods:18 patients with B aortic dissection involving the arch who were admitted into our center from November 2017 to January 2019 were enrolled, to evaluate the intraoperative and postoperative conditions, including special intraoperative treatment, time of operation、poseoperative drainage、time of use ventilators, time of staying in ICU, complications etc, 12-24 months follow-up were performed after operation.Results:No death occurred, 1 case with acute renal failure, 1 case with type I endoleak, 1 case with paraplegia occurred during hospitalization, 1 patient with sudden vomiting of blood 30 days after discharge from hospital who was found aortoesophageal fistula, underwent emergency surgery to replace thoracic aortic and repair esophageal fistula, all of them were cured and discharged, the rate of complication was 22.2%(4/18). none of the other patients had any phenomena such as agnail、distal rupture、twisted or displaced of the stents、ischemic of coronary artery、cerebrovascular accident, etc.Conclusion:The result of upper sternal mini-incision with debranching technique in B aortic dissection involving the arch is satisfied, the early and mid-term survival rate is significantly improved, the patient's prognosis are improved.
6.Clinical treatment of acute type-A aortic dissection with lower limb malperfusion
Cong CUI ; Li ZHANG ; Xia GAO ; Xianghui ZHANG ; Changbo XIAO ; Wei LU ; Gang WU ; Pingfan WANG
Chinese Journal of Thoracic and Cardiovascular Surgery 2018;34(10):593-596
Objective To explore the treatment experience of acute type-A aortic dissection with lower limb malperfusion.Methods From December 2012 to December 2016,479 cases of acute type A aortic dissection were treated surgically,including 39 patients with lower limb ischemia,including 27 males and 12 females,with mean age of(5 1.4 ± 12.4) years.All patients were treated with deep hypothermic circulatory arrest and were treated with single pump,double-tube and double-injected limbs.According to the patient's lower limb ischemia time,symptoms and signs,limb ischemia was assessed.If necessary,femoral artery-femoral arterial bypass was performed.For patients undergoing femoral arterial-femoral prosthetic bypass during the same period,postoperative follow-up monitoring,if necessary,secondary femoral-femoral arterial vascular bypass or osteofascial decompression.Results Early mortality rate was 17.9% (7/39).32 cases of postoperative survival.The follow-up rate was 93.8% (30/32),3 months to 3 years after the operation,the results were satisfactory.The over lower limb malperfusion recovery rate of follow-up patients was 96.7% (29/30).Conclusion Positive operation for acute type-A aortic dissection with lower limb malperfusion is safe,feasible and effective.Concomitant or secondary bypass procedures are also possible to restore distal perfusion when necessary.Comprehensive evaluation of patient' s status is strongly recommended for optimal surgical decision making.
7.The application of deep hypothermic circulatory arrest in the surgical treatment of complex thoracoabdominal aortic aneurysm
Cong CUI ; Li ZHANG ; Xia GAO ; Xianghui ZHANG ; Kexiong SUN ; Changbo XIAO ; Gang WU ; Shen MA ; Yuxin CHEN ; Pingfan WANG
Chinese Journal of Thoracic and Cardiovascular Surgery 2019;35(5):303-306
Objective To discuss the application of deep hypothermic circulatory arrest in surgical treatment of complex thoracoabdominal aortic aneurysms and its near-midterm effect.Methods The clinical data of 34 cases of thoracoabdominal aortic aneurysm in the center from August 2009 to June 2018 were analyzed retrospectively.All the patients underwent surgery under deep hypothermic circulatory arrest.There were 23 males and 11 females; aged 23 -67 years, mean(42.26 ±10.96) years old; Crawford type Ⅰ in 12 cases and Crawford type Ⅱ in 22 cases; aneurysms with a maximum diameter of 50 -120 mm, mean(65.26 ±16.09) mm;Marfan syndrome 15 cases, atherosclerosis 14 cases, aortic coarctation in 5 cases;22 cases of hypertension;28 cases of first aortic surgery, 6 cases of re-aortic surgery.Surgical transthoracic and abdominal incision, ext-racapsular approach, femoral artery and inferior vena cava intubation, deep hypothermic circulatory arrest technique to complete proximal anastomosis, arterial tube reconstruction of intercostal artery, abdominal organ blood supply artery and four The bifur-cated vessels were anastomosed, and the bifurcated vessels were anastomosed with the "Y"type artificial blood vessel trunk. The bilateral radial arteries were end-to-end anastomosis in the 10 mm artificial blood vessels of the "Y"type artificial blood vessels.Results There were no complications of cranial nerve system in the whole group , deep hypothermic circulatory arrest (17.68 ±4.88) min, ventilator assist time(34.88 ±16.04) hours, postoperative renal failure in 5 cases, after CRRT treat-ment After recovery, 1 case of paraplegia after operation, muscle strength recovered after cerebrospinal fluid drainage and de-compression, and 1 case died in the whole group, and died of multiple organ failure.The patients were followed up for 3 months to 5 years, and the results were satisfactory.The survivors did not die.The survivors did not die.However, 5 patients underwent thoracic aortic replacement under deep hypothermic circulatory arrest for the first time , and 4 patients underwent reo-peration because of distal vasodilation.The reconstructed intercostal artery occlusion occurred in 4 patients, but no paraplegia occurred.Conclusion When cross clamping the aorta is not feasible,it is safe to perform proximal anastomosis with deep hy-pothermic circulatory arrest.
8.Supra-arch branch vessel bypass and thoracic endovascular aortic repair for treating type B1C aortic dissection
CUI Cong ; ZHANG Li ; GAO Xia ; ZHANG Xianghui ; SUN Kexiong ; XIAO Changbo ; WU Gang ; MA Shen ; CHEN Yuxin ; WANG Pingfan
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery 2019;26(2):121-124
Objective To evaluate the results of a hybrid procedure for treating Stanford type B1C aortic dissection. Methods In our center, 49 patients with Stanford type B1C aortic dissection underwent supra-arch branch vessel bypass and thoracic endovascular aortic repair (TEVAR) from December 2013 to December 2017. There were 33 males and 16 females with an average age of 60.4±5.5 years. Left common carotid artery to left subclavian artery bypass (n=29), right common carotid artery to left common carotid artery and left subclavian artery bypass (n=18), left common carotid artery to left subclavian artery and right common carotid artery to right subclavian artery bypass (n=2) were performed. Results Early mortality rate was 2.0% (1/49). Forty-eight patients survived postoperatively. The follow-up rate was 100.0% (48/48). The patients were followed up for 6 to 47 (26.8±11.9) months postoperatively. Chest pain relapsed in one patient 8 months after the operation. The whole aorta CTA showed type A1S aortic dissection in one patient 6 months after the operation, and the re-operation was satisfactory. There was no endoleak or paraplegia. Conclusion Initial results suggest that the one-stage hybrid procedure is a suitable therapeutic option for type B1C aortic dissection.
9.Removal of benign tumor in the lower pole of the parotid gland through concealed incision in the retroauricular sulcus
WU Pingfan ; CHEN Linlin ; CHEN Fen ; GUO Lingyan ; LI Yu ; LEI Zhenge ; KE Xing ; TAN Weibing
Journal of Prevention and Treatment for Stomatological Diseases 2020;28(12):781-784
Objective :
To assess the safety and feasibility of incision in the retroauricular sulcus for removal of benign tumors in the lower pole of the parotid gland and to provide some ideas for aesthetic consideration of parotidectomy.
Methods:
In total, 18 cases with benign tumors of the lower pole regions of the parotid gland were included in this study, including 9 pleomorphic adenomas, 2 myoepitheliomas, 5 Warthin tumors, 1 basal cell adenoma and 1 oncocytoma. Three months after the operation, facial paralysis and salivary fistula were assessed. A visual analog scale was used to score the cosmetic satisfaction of the surgical incision. Tumor recurrence was followed up 6 ~ 12 months after operation.
Results:
In 18 patients with benign tumors the lower pole regions of the parotid gland, the tumor diameter ranges from 1.0 to 3.1 cm, with an average value of 2.5 cm. All patients experienced successful complete removal of the parotid mass with the minimally invasive retroauricular approach, and all wounds healed in one stage after operation. No serious complications, such as permanent facial paralysis and tumor recurrence, occurred 3 months after the operation. The patients were satisfied with the appearance of the surgical incision (aesthetic score 9.3 ± 0.4), achieving the expected aesthetic effect.
Conclusion
This approach is feasible and safe for most small benign parotid tumors located in the lower pole region of the parotid gland and in the posterior region of the jaw. The scar is located in the retroauricular sulcus, which significantly meets the aesthetic needs of the concealed incision for patients.
10.Early clinical experience of transcatheter aortic valve implantation via apical approach for high-risk aortic valve disease in single-center
ZHANG Li ; WANG Pingfan ; WANG Fengling ; LI Yuzhen ; LIU Haixia ; LIU Jianhua ; LIU Xuping ; XIAO Changbo ; GAO Xia ; WU Gang ; ZHANG Xianghui ; CUI Cong ; CHEN Yuxin ; ZHENG Yi
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery 2019;26(12):1194-1198
Objective To summarize the clinical experience in the treatment of high-risk patients with severe aortic valve disease by transcatheter aortic valve implantation (TAVI) via heart apex approach and to evaluate the early efficacy. Method Five patients who underwent TAVI via heart apex approach from September 2017 to February 2019 in Henan Thoracic Hospital were retrospectively analyzed, including 3 males and 2 females, aged 65-84 (74.6±4.5) years. Result All operations were performed through a small left incision into the thoracic cavity (3-5 cm), and then through the J-Valve transport system, the aortic valve was successfully released via heart apex after precise positioning under digital subtraction angiography. One patient developed ventricular fibrillation during the operation, and the operation was completed with the assistance of emergency femoral arteriovenous catheterization cardiopulmonary bypass; one patient underwent percutaneous coronary intervention first because of severe coronary stenosis; one patient had paroxysmal atrial fibrillation during the perioperative period, and had hepatorenal insufficiency and thrombocytopenia after the operation, and was improved after medical treatment; one patient had perivalvular leak during the operation, and was improved after re-implantation of the valve; one patient was in stable condition during operation and recovered smoothly after operation. Surgery was successful in all 5 patients. The follow-up time was 2-19 months, and the early clinical effect was good. Conclusion The short-term clinical efficacy of TAVI via heart apex approach in the treatment of high-risk severe aortic valve disease is definite and safe, but the long-term and medium-term effects need to be further evaluated.