The changes of arginine vasopressin (AVP) levels in plasma in some physiological states in healthy men were studied by RIA. Mean plasma AVP concentration in 30 normal adults after 12 h of overnight water deprivation was 10.6?2.5 pg/ml, and decreased from 11.85?6.0 to 1.8?1.6 pg/ml 1 h after an oral water load (20 ml/kg) administered in 16 dehydrated normal subjects (P

Peking Union Medical College is the earliest college to launch the clinical medicine specialty of 8-year program.The achievements that our college obtains are obvious to all.The education item of admission for 7-year switching to 8-year in the clinical medicine specialty was started to put in practice in 1995 and has been carried out for 12 years.The item has accelerated the flourish of science,facilitated the diversification of students' source and knowledge configuration and brought out a large quantity of high level medical persons with high quality The successful fulfillment of the education item of admission for 7-year switching to 8-year in the clinical medicine specialty has enriched our experiences of running college and explored a new mode of training high level medical persons for adopting to the situation of our country.

Objective To explore cephalosporinase from nosocomial Klebsiella pneumoniae infection and their drug-resistant characteristics among the ICU patients so as to provide an instruction for rational clinical medication.Methods 67 samples were identified with VITEK-60 automated system.The strains producing AmpC β-lactamases were screened with cefoxitin disk diffusion method recommended by the CLSI,and confirmed by cefoxitin three-dimensional test.AmpC β-lactamase genotype was differentiated by PCR-sequencing and susceptibility tests which were done with the Kirby-Bauer method recommended by the CLSI.Results In the 67 isolates of Klebsiella pneumoniae,11 strains(16.4％) were found to produce AmpC β-lactamases.The drug-resistant genotype for all the 11 AmpC-positive strains was DHA-1.AmpC-producing strains developed multi-drug resistance,especially for broadspectrum β-lactam antibiotics and enzyme inhibitors.β-lactamases-producing strains were more resistant than non-producing ones.Conclusion Klebsiella pneumoniae in ICU patients has a higher proportion of producing AmpC β-lactamase strains,which are all of DHA-1 genotype and have multi-drug resistance.

Objective To hy out a course of nursing intervention programmes for patients undergoing coronary intenrentional therapy on the basis of the health belief model(HBM),and estimate its clinical effectbv measuring the change ofquality of life(QOL).Methods 64 patients were randomly selected and divided into 2 groups,the experimental group was treated with the nursing intervetnion on the basis of the HBM,and the control group was treated with routine nursing measures.The quality of life wes compared between the two groups after intervention.Results The total score of QOL,the restricted ability of activity,the therapy satis-faction and the subiective feelings of patients to disease of the two groups had significant difference after inter- vention,P<0.01,but no difference in angina stabilization and occurrence was seen,P>0.05. Conclusions Nursing programmes on the basis of the HBM make the QOL of patients to improve evidently.

Arrhythmogenic right ventricular cardiomyopathy(ARVC) is a cardiac muscle disease characterized by peculiar right ventricular involvement that precipitates ventricular arrhythmias and sudden death.ARVC is a major cause of sudden death in the young and athletes.It is familial origin in 50% to 70% of cases,which follows an autosomal in heritance pattern.The pathology consists of a genetically determined dystrophy of the right ventricular myocardium with fibrofatty replacement.Clinical diagnosis can be achieved by demonstrating functional and structural alterations of the right ventricle,depolarization and repolarization abnormalities,arrhythmias with the left bundle branch block and fibro-fatty replacement through endomyocardial biopsy.Clinical research has indicated that successful treatment of ARVC is based on lifestyle modifications,prophylactic therapy(antiarrhythmic drugs,catheter ablation and implantable cardioverter defibrillator)to prevent sudden death.

Professional development of faculty is an essential component of strategy for medical schools to construct teaching team.Development of education is dependent upon the professional quality of teaching staff.Starting from connotation of faculty's professionalism,this paper compared present status of composition of teaching staff in China with that in foreign countries,explored the potential approaches for medical schools to strengthen the construction and sustainable development of teaching staff.

In order to meet the needs of increased requirement of nurse especially in the region with limited resources for education and training, PUMC Nursing School initiated a program of Day School Student since 2002. This paper reviews the enrollment, education and training of these students and to share our experience with other schools in China in terms of strategy development and program implementation.

In order to meet the needs of increased requirement of nurse especially in the region with limited resources for education and training,PUMC Nursing School initiated a program of Day School Student since 2002. This paper reviews the enrollment,education and training of these students and to share our experience with other schools in China in terms of strategy development and program implementation.

Objective:To explore the effects of nutritional intervention on the nutritional status,cognitive function and activities of daily living (ADL) in patients with Alzheimer's Disease (AD).Methods:90 AD patients were randomly divided into the control group and the intervention group,with 45 cases in each group.Patients in the control group received anti-dementia drugs,and patients in the intervention group additionally received TPF-T as the oral nutritional supplement.The nutritional status and nutritional biochemical indicators,cognitive function and ADL of two groups were evaluated when enrolled and 6 months later after the treatment.Results:After 6 months'treatment,the nutritional status,MMSE,ADL scores and nutritional indicators of patients in the intervention group were significantly improved compared to the control group (P ＜ 0.05).Conclusion:Nutritional intervention can effectively improve the nutritional status,cognitive function and ADL of patients with dementia.

Objective:To study the curative efficacy of functional training focusing on muscle group around shoulder for subacromial impingement syndrome.Method:Forty five patients with subacromial impingement syndrome (SIS) were randomly grouped into three groups (fifteen patients for each group).Patients in Group Ⅰ were trained only on muscles around scapula.Patients in Group Ⅱ were treated on rotator cuff muscles.While patients in Group Ⅲ were treated on both.The training goes every 2 days and last for 4 weeks.The indexes for evaluating curative efficacy included:the Neer-test,the Hawkins-test and the Peen Shoulder Score.These indexes were measured immediately and three months after the four week treatment.Result:After treatment of the functional training focusing on muscle group around shoulder,Neer-tests and Hawkins-tests of all of patients were changed from positive to negative,the degree of pain compared with pain before the treatment declined apparently(P＜0.01),at the same time,the degree of satisfaction and the function went up remarkablely(P＜0.01).Compared with group Ⅰ and group Ⅱ,it dropped the most notably on the degree of pain in the group Ⅲ(P＜0.01),however,the degree of satisfaction and the function rose most apparently (P＜0.01) Conclusion:The curative efficacy of functional training focusing on muscle group around shoulder for sub-acromial impingement syndrome was effective apparently.But the efficacy of treated focusing on both muscles around scapula and rotator cuff was the most remarkably.