1.Study on the relationship between Acute Coronary Syndrome and serum homocysteine
Chinese Journal of Primary Medicine and Pharmacy 2012;19(16):2432-2433
ObjectiveTo discuss the relationship between serum homocysteine (Hcy) level and severity of acute coronary syndrome(ACS) through measuring the level of serum Hey in the patients with ACS.Methods95 patients who were diagnosed ACS were divided into two groups:40 cases of unstable angina(UA) and 55 cases of a cute myocardial infarction(AMI).30 individuals were chosen as normal control(NC).In addition,according to the results of coronary angiography,the same 95 patients were further divided into three subgroups which were single-vessel disease( 28cases),double-vessel disease ( 36cases ) and multi-vessel disease ( 31 cases ).Level of serum Hcy was measured in all groups.ResultsSerum Hcy level of ACS patients was significantly higher than NC group( P < 0.01 ).The level of serum Hcy in AMI group was significantly higher than that in UA group( P < 0.05 ).The Hcy level in the multi-vessel disease group,double-vessel disease group and single-vessel disease group were increased in turn,and the difference of pairwise comparison was statistically significant ( P < 0.05 ).ConclusionThe serum Hcy level has rela tionship with the severity of coronary lesions and is directly proportional to the number of coronary artery lesions.The result suggests that the level of serum Hcy maybe play an important role in the prevention,diagnosis,treatment and monitoring of ACS.
3.Impact of nursing intervention on the secondary infection in chemotherapy of elderly patients with lung cancer
Chinese Journal of Practical Nursing 2013;(18):48-49
Objective To investigate the effect of intensive nursing intervention on the secondary infection in chemotherapy of elderly patients with lung cancer.Methods 168 cases of elderly lung cancer patients whose neutrophil ≤ 1.0×109/L during chemotherapy were randomly divided into two groups,namely,the intensive care group and the control group,with 84 cases in each group.The control group was given routine nursing of infection prevention,while the intensive care group was given intensified nursing for infection prevention.A contrastive analysis was conducted in terms of the incidence,clinical characteristics and the duration of antibiotic treatment of the two groups of patients with secondary infection.Results The secondary infection rate of the intensive care group was lower than that of the control group during chemotherapy.What's more,the duration of fever and treatment of the intensive care group was shorter than that of the control group,hence the patients were safe during infection period.The difference was statistically significant.Conclusions Strengthening the nursing intervention can reduce the incidence rate of secondary infection in aged patients with lung cancer,increase the tolerance of patients to chemotherapy and ensure the successful completion of the chemotherapy cycle,prolong the life span of the patients with an improved quality of life.
7.Influence of ERK1/2 signal-transduction pathway on differentiation of mesencephalic neural stem cells induced by bone marrow stromal cell-conditioned medium
Academic Journal of Second Military Medical University 1985;0(06):-
Objective:To investigate the effect of the ERK1/2 signal-transduction pathway on differentiation of rat mesencephalic neural stem cells(NSCs)in presence of bone marrow stromal cell-conditioned medium(BMSCs-CM)in vitro.Methods:NSCs were cultured on poly-L-lysine(PLL)coated 35 mm dishes.The neurospheres adhered to the bottom 30 min later;then the culture medium of natural differentiation group was replaced by neurobasal medium containing 2% B27;the control group was replaced with BMSCs- CM;and the inhibition group was replaced with BMSCs-CM containing PD98059(5?mol/L).The proportions of neurons and astrocytes and their morphological difference were observed by immunocytochemistry technique 7 d later.Results:We successfully cultured NSCs from adult rat BMSCs-CM.The proportion of neurons in the natural differentiation group(15.70?10.3)% was lower than that in the control group([51.17?10.30]%,P
8.A Research on Some Legal Problems for Sex-change Surgery
Chinese Medical Ethics 1994;0(06):-
The sex - change has been applied in clinic for about twently years. But there was no correlative law so far. It appeared law cases uninterrupted in recently years, which accompanied a simply on the legality, freedom for decision of the sex - change surgery and sexual testification after the surgery.
9.Relationship Between A1675G Polymorphism of Angiotensin II type 2 - receptor Gene and Essential Hypertension
Journal of Chongqing Medical University 2003;0(06):-
0.05). conclusion; The frequency of A allele in essential hypertension is higher than that in control group, but there is no statistical significance. The relationship between AT2R gene A1675G polymorphism and essential hypertensive patients of the Chinese Han nationality population.
10.Immunopharmacological Studies on LWDHW and RGL
Chinese Journal of Immunology 1985;0(05):-
The effect of Liu Wei Di Huang Wan(LWDHW)and Rehmannia glutinosa Libosch(RGL)on the immune function of normal and immune-suppressed mice were observed.The results showed that the two medicinal herbs given orally can correct the suppres-sive effect of cyclophosphamide on spleen and thymus weight,serum specific antibodylevel and lymphocyte transformation.They can also improve the phagocytic activity ofperitoneal macrophages and enhance peripheral blood ANAE~+ lymphocyte ratio of mi-ce.Under the same conditions,no obvious effect of LWDHW and RGL on the normalmice was found except that RGL can increase the antibody level of normal mice.Theresults implicate that LWDHW and RGL may have some immunomodulatary effect.