1.Ehtical Thinking About Carrying out Humanistic Service And Management in Maternity
Chinese Medical Ethics 1995;0(02):-
Service for childbirth is obviously special.Because every tache in childbirth can affect the health and life safe of babies and mothers.At present the humanistic service is still not popularized in maternity of hospitals.So it is possible to happen contradictions or bothers between doctors and patients.Therefore,thinking from ethics,we should adopt effective measures,develop the humanistic service and management,and satisfy the lying-in women completely,to establish harmonious relationships between doctors and pationts
2.Clinical study of telbivudine on HBeAg-positive chronic hepatitis B
Chinese Journal of Primary Medicine and Pharmacy 2011;18(2):165-167
Objective To investigate the curative effect of telbivudine versus lamivudine in chronic hepatic B with a therapy of 48 weeks. Methods 94 patients who were diagnosed chronic hepatitis B were investigated. The therapeutic group and the control group (n = 47) were respectively assigned to receive 600mg of telbivudine and 100mg of lamivudine in 48 weeks. Copies of HBV-DNA、serum markers、alanine transarninase(ALT) level were tested before therapy and 4 weeks、12 weeks、24 weeks、48 weeks in the the course of treatment. The HBV-DNA conversion、HBeAg conversion and the normal rate of the ALT were compared. Results The copies of HBV-DNA decreased as the treatment progressing,especially at the 4 thweek. Conversion rate of the HBV-DNA of the telbivudine group was 72.3% ,which was higher than the lamivudine group 42.6%. There is a significant difference between two groups (x2 = 8.530,P < 0.05). 95.7% of ALT in the telbivudine group revived to normal level versus 91.5% of the lamivudine group became normal. There is no significant difference between two groups (P > 0.05). At the end of treatment,the rate of the HBeAg converting to negative in the telbivudine group is 38.3% versus the lamivudine group 31.9%, but there is no significant statistical difference between two groups(x2 = 0.420 ,P > 0.05). The frequence of seroconversion of HBeAg in the telbivudine group is 23.4% versus the lamivudine group 17.0%, but no statisticall difference between two groups (x2 = 0. 594, P > 0.05). Conclusion It was more effective to treat the HBeAg positive chronic hepatitis with telbivudine than lamivudine,and lower frequence of seroconversion of the HBV-DNA、HBeAg.
3.Plantar pressure of normal people with different body mass index
Chinese Journal of Tissue Engineering Research 2017;21(23):3730-3735
BACKGROUND:Body mass is a critical factor affecting plantar pressure,and the systematic study on plantar pressure with different body mass has not been reported.OBJECTIVE:To measure the plantar pressure of normal people with different body weight,so as to provide reference for the application of plantar pressure.METHODS:Totally 80 healthy people with different body weight were enrolled,and the dynamic plantar pressure was measured by the Footscan 2 meter flat foot pressure distribution system (RSscan,Belgium).The participants were divided into four groups (n=20 per group) according to the classification criteria for prevention and control of overweight and obesity in Chinese adults,such as underweight,normal weight,overweight group,and obesity groups,and a comparative analysis was conducted.RESULTS AND CONCLUSION:(1) The peak pressure and impulse of each region of the foot were significantly increased with body mass index increasing (P < 0.05).Compared with the normal weight people,the pressure of the part foot area of the overweight subjects and each part foot area of the obese subjects were significantly increased (P < 0.05).(2) The percentage of the medial plantar contact area accounting the total contact area of the foot was significantly increased with body mass index increasing (P < 0.01);the percentage in the obese group was significantly higher than that in the normal group (P < 0.05).(3) These results show that the plantar pressure and impulse are increased in overweight and obese subjects due to weight gain,and foot will appear with pathological changes with time going.Obese people suffer from arch drop due to weight gain,and increase in contact area of midfoot,which are easy to cause flatfoot.Overweight especially obese,should pay attention to control weight,do appropriate exercise,wear suitable shoes,protect the foot,further to prevent the occurrence of foot injury and flatfoot.
4.The Current Status and the Development Strategy of Sci-tech Novelty Retrieval Center in a Military hospital
Chinese Journal of Medical Science Research Management 2015;28(2):139-142,146
Objective examine the current status of Science and Technology Novelty about Medicine and Health Sciences in the Guangzhou Military Region during 2010 to 2013.Methods Using Microsoft Excel software to conduct statistical analysis on data that including the novelty of the client' s new projects,subject classification,the level of project award application,client unit,type of requested projects,innovative items,etc.Results The total number of applying for project innovation checking showed a decreasing trend in the Guangzhou Military Region;the majority of awarded application was for the third Prize;and the requirested for new project innovation checking is far less than project innovation award checking.Conclusions The center should actively promote the understanding for the innovation of the new projects among the research groups,and improve the class of prize award.
5.Experimental study of Gold Theragran on rennin angiotensin system in diabetic nephropathy
China Journal of Traditional Chinese Medicine and Pharmacy 2005;0(03):-
Objective:To explore the molecular mechanism of Gold Theragran in the protection of renal function,and the inhibition of renal local rennin angiotensin(RA)system in the early diabetic nephropathy(DN),and to provide the theoretical and experimental data for clinical application to prevent the DN.Methods:The experimental rats consisted of 64 healthy SD rats,average 180-220g,female and male both a half,rat model of DN was established by improved method of YANG Junwei,s method of intraperitoneal injection of STZ after nephrectomy.8 Rats was taken as normal group,the rest of them were randomly divided into 5 groups:high,middle and low dose groups of Gold Theragran,Valsartan group,model group.In each group,blood glucose,blood lipids,urine microalbumin per 24 hours,KW/BW,renal angiotensin converting enzyme,plasma and renal angiotensin Ⅱ,and its type 1 receptor were observsd and measured.Results:①Rat's general status in each treatment group was improved compared with the DN model group.②The levels of serum glucose decreased in all treatment groups,especially the high-dose group and mid-dose group were significant(P0.05).③The levels of abnormally high lever of TG,TC decreased in treatment groups,especially the high-dose group and mid-dose group were significant(P0.05).The high-dose group had further function to regulate the lipids in the 28th day than in the 7th day(P0.05).Conclusion:Firstly,Gold Theragran had a therapeutic effect of protecting the renal function on the experimental DN rats;Secondly,Gold Theragran can inhibit the abnormal state of activated rennin angiotensin system in diabetic nephropathy,delay the development of diabetic nephropathy;Thirdly,with the treatment course prolonged,the effective of Gold Theragran might be more obvious,and different dose groups show dose-effect-dependent relationship.
6.Studies on Individual Biomass and Alkaloid Content of Wild Coptis on Mt. Emei
Chinese Traditional and Herbal Drugs 1994;0(08):-
The structure and trends of individual organic biomass and alkaloid content of two wilCoptis species, C. omeiensis and C. gulinensis, on Mt. Emei, were studied by testing and analy-psing samples collected from several points. The results were compared with two cultivated C.species, C. chinensis and C. deltoidea. The accumulative characters and laws of biomass andeffective composition of the two wild species were revealed.
7.The effects of irbesartan on the endothelial dysfunction in the elderly with essential hypertension
Chinese Journal of Geriatrics 2000;0(04):-
Objective To investigate (1) whether or not irbesartan can relieve endothelial dysfunction of essential hypertension; (2) which of fosinopril and irbesartan is better in relieving the endothelial dysfunction in essential hypertension, especially for the elderly . Methods Sixty-two elderly patients with essential hypertension were divided into two groups: fosinopril group and irbesartan group. After 3 months treatment, the effect of drugs on BP and the endothelium-dependent relaxation(EDR) of brachial artery (BA) with high resolution ultrasound examination were analyzed, meanwhile the plasma levels of NO、ET-1 and vWF were assessed. Results Fosinopril and irbesartan groups had a similar (P
8.Determination of Potassium Chloride in Compound Sodium Chloride Injection by Sodium Tetraphenylborate Volumetric Method
China Pharmacy 2005;0(14):-
OBJECTIVE:To establish sodium tetraphenylborate volumetric method in place of gravimetric analysis method for the determination of the content of potassium chloride in compound sodium chloride injection.METHODS:The contents of potassium chloride in compound sodium chloride injection were determined by sodium tetraphenylborate volumetric method and sodium tetraphenylborate gravimetric method respectively,the results of which were compared.RESULTS:The average recovery of volumetric method was99.75%(RSD=0.46%,n=9),there was no significant difference in the t-test comparison between the determination results of volumetric method and that of the gravimetric method.CONCLUSION:The sodium tetraphenylborate volumetric method is simple,fast and accurate,which can take the place of gravimetric method for the deter?mination of contents of potassium chloride in compound sodium chloride injection.
9.Comparison of Chinese medicine treatment of juvenile and adult seasonal allergic rhinitis
Chinese Archives of Otolaryngology-Head and Neck Surgery 2006;0(05):-
OBJECTIVE To study the treatment effect of traditional Chinese medicine on juvenile seasonal allergic rhinitis.METHODS The patients with allergic rhinitis presented to the clinic three or more times included in this study.All of the patients were treated with traditional Chinese medicine and divided into young group and adult group.Symptom score were recorded in each time presented to the clinic.RESULTS There were 15 patients cured, 30 patients improved and 0 patients unimproved in the young group.While, in adult group, there were 10 patients cured, 21 patients improved and 10 patients unimproved.There was a significant difference between the two groups(?2=29.0323, P
10.Analysis of Antihypertensives Used in 27 Hospitals of Chongqing During the Period 1999~2001
China Pharmacy 2001;0(12):-
OBJECTIVE:To review the situation of antihypertensives used in hospitals of Chongqing City METHODS:The sum of money,DDDs and daily cost of antihypertensives consumed during the past three years were analysed RESULTS:Consumption sum of antihypertensives in the period 1999~2001 was increasing year by year During this period,the costs of calcium antagonists and ACEI accounted for 44 59% and 33 55% of the consumption sum,respectively,while the domestic drugs showed an increasing tendency,the drugs produced by joint ventures and the imported drugs decreased steadily Among this kind of drugs,Nifedipine and Captopril were much more frequently used than others,and Felodipine occupied the first place in the cost list CONCLUSION:It is necessary to develop the long-effect antihypertensives that fulfill the domestic need