Objective:To evaluate the clinical effects of the key-way attachment in fixed restoration of mandibular first and second molar deletion.Methods:A 1 -5-year follow-up study was conducted on 1 6 patients with the reconstruction of mandibular first and second molar deletion.The key-way attachment was used as a connector in the fixed partial denture,with the third molar and 2 sec-ond premolars as the abutments.Results:During 5-year follow-up,1 3 of the fixed partial denture were good-looking,stable and functioning.The abutments were stable,without endodontic and periodontal disease.No absorption of alveolar bone was observed by X-ray examination.3 cases were failure.Bleeding on probing of third molar was observed in 1 patient 1 year after restoration.1 re-tainer of a denture on the third molar was loosing 1 .5 years after restoration.1 patient had dental caries on the third molar 5 years af-ter restoration.Conclusion:The key-way attachment as a connector is useful in fixed partial denture in patients with mandibular first and second molar deletion.

Objective To observe effects of soaking therapy with traditional Chinese medicine on athlete's foot. Methods346 cases of the treatment group (175 cases of erosive type and 171 cases of bullous type) were treated with soaking therapy by traditional Chinese medicine and 335 cases of the control group (170 cases of erosive type and 165 cases of bullous type) were treated with 3% Clotrimazolum ointment. Effects of two groups were compared.Results Effect of the treatment group was obviously more superior to that of the control group (P<0.0001). ConclusionsIt shows easy and effective that patients with athlete's foot were treated by soaking therapy with traditional Chinese medicine.

Objective To study the correlations between diopter,axis length,cornea curvature and thickness in myopia patients. Design Prospective case series.Participant 300 myopic patients who were ready for LASIK.Method 300 myopic patients who were ready for LASIK were selected randomly.They were divided into four groups according to the diopter of myopia:low myopia group (≤-3.00D)41 cases,medium myopia group(＞-3.00D,≤-6.00D)130 cases,high myopia group(＞-6.00D,≤-9.00D)95 cases,and super myopia group(＞-9.00D)34 cases.The axis length,cornea thickness,cornea eurvture and diopter of myopia were detected. Through analysis of variance(ANOVA),Pearson correlation analysis and linear regression analysis,the correlations between axis length, cornea thickness,curvature and diopter of myopia were made out in four groups.Main Outcome Measure Diopter of myopia,cornea curvature,axis length of eye and central cornea thickness.Result The axis length of low myopia group,medium myopia group,high myopia group and super myopia group was(24.32?1.73)mm,(25.33?1.49)mm,(26.04?1.92)mm,(27.47?2.57)mm respectively. There were obvious differences of axis lengths between four groups(P=0.000).The cornea curvature in high myopia group was obviously different from those in low myopia group and medium myopia group.There were no significant differences of cornea thickness among four groups(P=0.409).The axis lengths of eyes respectively had correlations with diopters(r=0.734,P=0.000),vertical and horizontal cornea curvatures(r=-0.312,P=0.000;r=-0.328,P=0.000).Conclusion The main effective factor on the diopter of myopia is the axis length for most patients.For the patients with high myopia,the cornea curvature is another effective factor.With the increase of axis length,the cornea curvature decreases,and the cornea turns flatter.(Ophthalmol CHN,2006,15:321-323)

Objective :To study the two common method of internal irradiation for nanometer-iron nuclide,and how to estimation of the absorbed dose for each of them.Methods:We chose the nanometer-iron nuclide emitting β-ray during the decay period,Respectively,Arterial injected into the liver or percutaneous puncture direct inject into the liver.Results:Through the formula,a few nanometer-iron nuclide can produced greater radiation.Conclusion:The estimation of absorbed dose depends on the therapy method.

Objective To investigate the clinical significance of the urine micro albumin(MA)and urine enzyme detections in early renal injury in children with allergic purpura.Methods 120 patients with allergic purpura were chosen as the research sub-jects and divided into the early renal injury group and non-renal injury group according to whether having the renal injury.Contem-poraneous 40 healthy children were chosen as the healthy control group.The urine MA and urine enzyme levels were detected and compared among the various groups.Results MA was (17.5 ±3.8)mg/L in the study group,transferring(TRF)was (0.56 ± 0.34)mg/L,β2-MG was (0.35 ±0.07 )mg/L,NAG was (18.6 ±5.1 )U/g,which were significantly higher than those in the healthy control group,the differences were statistically significant (P <0.05 );in the early renal injury group,MA was (42.1 ± 21.3)mg/L,TRF was (1.65±0.54)mg/L,β2-MG was (0.43±0.06)mg/L and NAG was (23.1±5.12)U/L,which were signif-icantly higher than those in the non-renal injury group,the differences had statistically significance (P <0.05).Conclusion The de-tection of urine MA and urine enzyme can be used as the indexes for monitoring the early renal injury in children with allergic pur-pura,and is conducive to early discovery,in time intervention and reduce the occurrence of complications.

In order to build a high-quality teaching group with excellent academics,strong innovation and comprehensive ability, the School of Public Health of CQUMS pays much attention to training young teachers,encouraging them to further their study and scientific research abilities as well as improving their comprehensive abilities.

This paper presents a new method of separating the junction between the epidermis and the dermis with enzyme,and then,observing the small wound of the papillary of the dermis by means of SEM.The result showed that this new method would be advantageous to the identification of small stab wounds and providing some concrete identify targets.

Expression of endogenous ouabain in placenta and the concentrations of serum ET-1 and NO were examined in 30 patients with hypertensive disorder complicating pregnancy (HDCP) and 30 healthy pregnant women to investigate the effect of endogenous ouabain on HDCP. Compared with the healthy pregnant group, the expression of endogenous ouabain dramatically increased in the HDCP groups (P<0.01). There was a significantly positive correlation between the expression of endogenous ouabain with ET-1 (r=0.5567, P<0.01), while the correlation of endogenous ouabain and NO was significantly negative (r=-0.6895, P<0.01). As expected, the correlation between ET-1 and NO was negative (r=-0.7796, P<0.01). ET-1 concentrations of maternal and cord sera in HDCP groups were significantly higher in comparison with healthy pregnant group (P<0.01). On the contrast, NO concentrations were much lower in the maternal and cord sera of HDCP groups as compared with healthy pregnant group (P<0.01). Our data suggest that endogenous ouabain is directly involved in the nosogenesis of HDCP, with accompanying decreased NO and the elevated of ET-1.
Case-Control Studies ; Endothelin-1/*blood ; Hypertension, Pregnancy-Induced/*metabolism ; Nitric Oxide/*blood ; Ouabain/*metabolism ; Placenta/*metabolism

OBJECTIVE:To identify different origin of Scutellaria amoena CH Wright and Scutellaria baicalensis Georgi indexed in China Pharmacopeia by HPLC fingerprints.METHODS:RP-HPLC method was adopted in which the samples were separated on Zorbax SB-C18(250mm?4.6mm,5?m)column at a column temperature of 30℃.The gradient elution was performed on the mobile phase which consisted of acetonitrile(contairing 1.0% methanoic acid)-water(containing 1.0% methanoic acid)at a flow rate of 1.0mL?min-1.The detection wavelength was set at 274nm.RESULTS:The fingerprints of Scutellaria amoena CH Wright that from different places were of great resemblance,so were the fingerprints between Scutellaria baicalensis Georgi that from different places,but the fingerprints between Scutellaria amoena CH Wright and Scutellaria baicalensis Georgi were of significant difference,with resemblance of only 0.859.CONCLUSION:The RP-HPLC fingerprint serves as basis for the further study of the quality criteria of Scutellaria amoena CH Wright and Scutellaria baicalensis Georgi.

Objective: To investigate the effect of Fu Zheng Hua Yu-319 Recipe on hepatic sinusoid capillarization in the rat of hepatic fibrogenesis. Methods: Hepatic fibrosis model rats were induced by intraperitoneal injection of dimethyl nitrosamine (DMN). thrice a week for 4 weeks, and they were divided into the treatment group which were treated with Fu Zheng Hua Yu-319 Recipe for 4 weeks, and the model control group. Serum and hepatic tissue were taken for examination of pathohistology, microstructure by electron microscopy, immunohistochemistry, and hydroxyproline content in the liver tissue and hepatic function. Results: In the normal group, peripheral cytoplasma of endothelial cells in the hepatic sinusoid is very thin with a lot of small fenestra, and no basement membrane under endothelium was found. In the model group, crookedness and stricture of the hepatic sinusoid were found , and the fenestra in cytoplasma of the endothelial cell reduced or disappeared with obvious basement membrane, and hemorrhage necrosis in the liver tissue could be found, with a great proliferation of connective tissue in the portal area, and fibrous septum extended towards into the lobuli, the content of hydroxyproline (HYP) in the liver tissue increased significantly. The VI factor-related antigen, a-actin of smooth muscle, LM and type IV collagen positive staining on the hepatic sinusoid wall increased significantly with a wider range as compared with the normal rat. In the treatment group, the extents of crookedness and stricture of hepatic sinusoid and reduction and disappearence of endothelial fenestra were lower, with thiner or discontinuous basement membrane, and a part of hepatic sinusoid construction approached to normal, and degeneration and necrosis of hepatic cells were mild and fibrous septum in the liver tissue decreased significantly, and HYP content decreased significantly (P