Service for childbirth is obviously special.Because every tache in childbirth can affect the health and life safe of babies and mothers.At present the humanistic service is still not popularized in maternity of hospitals.So it is possible to happen contradictions or bothers between doctors and patients.Therefore,thinking from ethics,we should adopt effective measures,develop the humanistic service and management,and satisfy the lying-in women completely,to establish harmonious relationships between doctors and pationts

Objective To investigate the curative effect of telbivudine versus lamivudine in chronic hepatic B with a therapy of 48 weeks. Methods 94 patients who were diagnosed chronic hepatitis B were investigated. The therapeutic group and the control group (n = 47) were respectively assigned to receive 600mg of telbivudine and 100mg of lamivudine in 48 weeks. Copies of HBV-DNA、serum markers、alanine transarninase(ALT) level were tested before therapy and 4 weeks、12 weeks、24 weeks、48 weeks in the the course of treatment. The HBV-DNA conversion、HBeAg conversion and the normal rate of the ALT were compared. Results The copies of HBV-DNA decreased as the treatment progressing,especially at the 4 thweek. Conversion rate of the HBV-DNA of the telbivudine group was 72.3% ,which was higher than the lamivudine group 42.6%. There is a significant difference between two groups (x2 = 8.530,P ＜ 0.05). 95.7% of ALT in the telbivudine group revived to normal level versus 91.5% of the lamivudine group became normal. There is no significant difference between two groups (P ＞ 0.05). At the end of treatment,the rate of the HBeAg converting to negative in the telbivudine group is 38.3% versus the lamivudine group 31.9%, but there is no significant statistical difference between two groups(x2 = 0.420 ,P ＞ 0.05). The frequence of seroconversion of HBeAg in the telbivudine group is 23.4% versus the lamivudine group 17.0%, but no statisticall difference between two groups (x2 = 0. 594, P ＞ 0.05). Conclusion It was more effective to treat the HBeAg positive chronic hepatitis with telbivudine than lamivudine,and lower frequence of seroconversion of the HBV-DNA、HBeAg.

Objective To discuss the application of image sensor in wireless endoscopic micro-electro-mechanical-system (MEMS). Methods Through the comparison of various types of image sensors, and in the consideration of the environment and requirement inside the body, CMOS image sensor which can output analog image signal with high density of integration, low power consumption, small profile was chosen as the sensor component of a wireless endoscope. The profile and power consumption of some specific models of this type of image sensor were compared and analyzed.Results The problems, such as ground connection, crystal configuration and the layout of circuit board, were reasonably solved during the design of image sensor's schematic circuit diagram. The image capture module based on OV7930 sensor was designed and manufactured. Images were successfully captured during the animal experiments.Conclusion The application and design of image sensor in a wireless endoscopic MEMS are feasible.

Objective:To explore the molecular mechanism of Gold Theragran in the protection of renal function,and the inhibition of renal local rennin angiotensin(RA)system in the early diabetic nephropathy(DN),and to provide the theoretical and experimental data for clinical application to prevent the DN.Methods:The experimental rats consisted of 64 healthy SD rats,average 180-220g,female and male both a half,rat model of DN was established by improved method of YANG Junwei,s method of intraperitoneal injection of STZ after nephrectomy.8 Rats was taken as normal group,the rest of them were randomly divided into 5 groups:high,middle and low dose groups of Gold Theragran,Valsartan group,model group.In each group,blood glucose,blood lipids,urine microalbumin per 24 hours,KW/BW,renal angiotensin converting enzyme,plasma and renal angiotensin Ⅱ,and its type 1 receptor were observsd and measured.Results:①Rat's general status in each treatment group was improved compared with the DN model group.②The levels of serum glucose decreased in all treatment groups,especially the high-dose group and mid-dose group were significant(P0.05).③The levels of abnormally high lever of TG,TC decreased in treatment groups,especially the high-dose group and mid-dose group were significant(P0.05).The high-dose group had further function to regulate the lipids in the 28th day than in the 7th day(P0.05).Conclusion:Firstly,Gold Theragran had a therapeutic effect of protecting the renal function on the experimental DN rats;Secondly,Gold Theragran can inhibit the abnormal state of activated rennin angiotensin system in diabetic nephropathy,delay the development of diabetic nephropathy;Thirdly,with the treatment course prolonged,the effective of Gold Theragran might be more obvious,and different dose groups show dose-effect-dependent relationship.

The structure and trends of individual organic biomass and alkaloid content of two wilCoptis species, C. omeiensis and C. gulinensis, on Mt. Emei, were studied by testing and analy-psing samples collected from several points. The results were compared with two cultivated C.species, C. chinensis and C. deltoidea. The accumulative characters and laws of biomass andeffective composition of the two wild species were revealed.

Recently,the interest in a new surgical procedure named natural orifice transluminal endoscopic surgery has blossomed worldwidely.During these several years,quite a number of natural orifice transluminal endoscopic surgery experiments have been carried out on porcine models and even on humans,including transvaginal cholecystectomies,transgastric appendectomies,transvaginal appendectomies,transvesical peritoneoscopies,etc.This review article aims to discuss the current research status and the challenges of orifice transluminal endoscopic surgery.

Early diagnosis and treatment can improve the outcomes of patients with gastrointestinal neoplasms. Although digestive endoscopy is considered as a best method to diagnose gastrointestinal neoplasms,some early stage,flat-type neoplasms may be overlooked by routine endoscopy. In recent years,endoscopic autofluorescence imaging( AFI)as a new technique, has been widely applied in clinical practice for enhancing the endoscopic diagnostic accuracy of gastrointestinal neoplasms,especially for early stage,flat-type neoplasms. This article reviewed the clinical application of AFI for diagnosis of gastrointestinal neoplasms.

Objective To investigate the protective role of Xiongbitong capsule against liver injury in hyperlipemic rats.Methods Sixty Wistar male rats were randomly divided into 5 groups(12 rats in each group): a blank group, a model group, a simvastatin group(10 mg/kg, 2 ml intragastric administration daily), a Xiongbitong capsule high-dose group(25 mg/kg, 2 ml intragastric administration daily), and a Xiongbitong capsule low-dose group(12.5 mg/kg, 2 ml intragastric administration daily). Hyperlipidemia model in rats was indeuced by hyperlipidemic diet. The simvastatin group was intragastric administrated with simvastatin suspension 2 ml(10 mg/kg daily), and the rats in the control group and the model group were intragastric administrated with equal volume of saline. After 10 weeks, the serum leves of total cholesterol(TC), triacylglycerol(TG), low-density lipoprotein cholesterol(LDL-C), high-density lipoprotein cholesterol (HDL-C), nitric oxide(NO), endothelin1(ET-1), and the whole blood viscosities(high-, medium-, low-shear)were measured. Liver injury were evaluated with histopathologic examination by H.E. staining. The expressions of intercellular adhesion molecule-1(ICAM-1), monocyte chemoattractant protein-1(MCP-1)in hepatic tissue were measured by immunohistochemical staining.Results The serum leves of TC(1.47± 0.10 mmol/Lvs. 3.48±0.19 mmol/L), TG(0.38±0.11 mmol/Lvs. 0.95±0.14 mmol/L), LDL-C(1.48± 0.18 mmol/Lvs. 2.39±0.22 mmol/L), ET-1(145.81±18.65 pg/mlvs. 177.70±17.70 pg/ml) in the Xiongbitong capsule high-dose group were significantly lower than those in the model group(allP<0.01), HDL-C(1.21±0.14 mmol/Lvs. 0.65±0.10 mmol/L)and NO(31.28±2.36μmol/Lvs. 19.61±1.28μmol/L) significantly lower than those in the model group(allP<0.01), the expressions of ICAM-1(0.133±0.019vs. 0.187±0.011)and MCP-1(0.153±0.014vs. 0.264±0.020)significantly lower than those in the model group(allP<0.01). The liver injury in the Xiongbitong capsule high-dose group decreased than that in the model group. Conclusions Xiongbitong capsule can protect against liver injury via regulating lipid metabolism, protecting endothelial function and down regulating expressions of MCP-1 and ICAM-1.

Objective: To analyze economic operation situation of public hospital of traditional Chinese medicine in Jiangsu. Methods: Through the investigation and analysis, to collect situation of hospital health resources, medical service, the resources utilization efficiency and balance. Based on the actual data on the present situation and the development of hospitals of traditional Chinese medicine, the systematic analysis of the income and expenditure was made. Results: The problems in the development of Chinese medicine hospitals and the countermeasures are found, references for the medical institution managers and the basis for policy makers are provided. Conclusion: Hospitals of traditional Chinese medicine need to continue deepening the reform, and actively developing the features of TCM advantages, finding their own positioning goals, trying to explore development service of traditional Chinese medicine and Chinese medicine products, so as to cultivate the self-core competitiveness.

Objective:To explore the necessity of monitoring polysomnography (PSG ) in snoring children.Method:The PSG were monitored in 162 children with snoring or apnea.Acording to results of PSG,162 cases were separated into two groups:group obstructive sleep apnea hypopnea syndrome(OSAHS) and group primary snoring(PS),monitoring data including:apnea hypopnea index(AHI),snoring index(SI),lowest oxygen saturation(LSaO_2) and time of SaO_2<0.9,all data were undertaked statistical analysis. Result:In all 162 snoring cases,150 cases(92.6%) belong to group OSAHS,12 cases(7.4%) belong to group PS;Differences of data of age,sex and body mass index(BMI) are not significant but that of AHI,SI,LSaO_2 and time of SaO_2<0.9 are significant(P<0.05).Conclusion:It's necessary to monitor PSG in snoring children for early diagnosis and correct treatment to avoid disadvantage of OSAHS.