Objective To explore the complications and influence of repeat cesarean section after previous cesarean delivery. Methods The styles of the total 67 cases of repeat cesarean section were reviewed, and the mater-nal ages, gestarional weeks, time intervals between the two times of delivery, and the styles of the previous cesarean section were analyzed. Results Of the total 67 case of repeat cesarean section ,there were 8 cases with relatively se-vere adhesion, 1 case with hysterectomy. There were 9 cases with intraoperative blood loss over 500ml(13.4%). The rate of adhesion induced by abdominal transverse incision of cesarean section was significantly higher than that of ab-dominal longitudinal incision of low cesarean section. Conclusions When we determining a style of cesarean section, we should comprehensively consider the obstetrical conditions of the pregnant women to select abdominal incision style and uterine incision style. The quality of previous cesarean delivery determines the complications of repeat cesarean section.

Objective To evaluate the similarity of dissolution profiles of self-produced and original drug cefuroxime axetil tab-lets.Methods Based on the dissolution detection method in the Chinese Pharmacopoeia,the dissolution behaviors of the self-pro-duced preparation and original drug were investigated in pure water,0.1 mol/L hydrochloric acid,0.05 mol/L hydrochloric acid, pH4.5 and pH6.8 medium and the rotation speed of 50,25,75 r/mim.The stripping curves were evaluated by the f2 factor method. Results In the rotation speed of 50 r/min,the f2 factors in different mediums were 57.65,79.17,73.56,66.83 and 62.33 respec-tively;the medium was 0.1 mol/L hydrochloric acid with the rotation speed of 25,75 r/min,the f2 factors were 65.35 and 78.48 re-spectively.Conclusion The stripping curves of self-produced preparation and original drug are similar under various conditions.

Objective: To explore the impedance characteristics of ear acupoints in stroke patients with excess or deficiency syndrome, and to provide basis data for objective study of the syndromes of stroke. Methods: The data of electrical characteristics of ear acupoints in stroke patients and healthy people were collected, and excess syndrome and deficiency syndrome of stroke were identified by quantifying the syndromes of stroke using scales. The differences in impedance characteristics of ear acupoints between stroke patients and healthy people were analyzed, and the differences in impedance characteristics of ear acupoints between stroke patients with excess syndrome and stroke patients with deficiency syndrome were analyzed too. The correlation among impedance characteristics of ear acupoints, stroke and the syndromes was also analyzed. Results: There were significant differences in impedance characteristics of ear acupoints between stroke patients and healthy people (P<0.05,P<0.01). The ear acupoints CO12 (Gan) and CO13 (Pi) had a significant role in diagnosing stroke as compared with CO18 (Neifenmi), AT3.4.AH12i (Naogan), CO10 (Shen), TG2p (Shenshangxian), AH6a (Jiaogan), AT4 (Pizhixia), and CO15 (Xin). There were significant differences in impedance characteristics of ear acupoints between stroke patients with excess syndrome and stroke patients with deficiency syndrome (P<0.05, P<0.01). The ear acupoints AH6a (Jiaogan) and CO10 (Shen) played an important role in differentiation diagnosis of excess syndrome and deficiency syndrome of stroke, followed by CO18 (Neifenmi), TF4 (Shenmen) and TG2p (Shenshangxian). Conclusion: Some ear acupoints with diagnostic value for stroke may provide basis of objective research for stroke diagnosis as well as identifying excess syndrome and deficiency syndrome of stroke.

Objective To study the expresion and significance of CXCR4 in gastric cancer(GC) and intra-abdominal metastasis.Methods Immunohistochemistry and PT-PCR were used to detecte the expresion of CXCR4 protein and CXCR4 mRNA in GC,lynph node metastasis(LNM),peritoneal metastasis(PM) and normal stomach(NM) tissues.Results There was no CXCR4 expression in normal gastric mucosa cell.The expression rate of CXCR4 in GC and PM was 59.4%,100% respectively(P

Objective To investigate whether different initial planes have an effect on examination of the fetal heart by four-dimensional ultrasound with spatiotemporal image correlation (STIC).Methods The standard examination planes of fetal heart were rendered using the heart volume data which were acquired in different initial planes with STIC,then these rendered planes were compared and scored.Results① At the four-chamber initial planes,the reconstruction rate of longitudinal planes of the aortic arch (46.27%) and the pulmonary artery (49.25%) were poor,in addition,the reconstruction showed low quality,and the average scores were 1.366 and 1.403,respectively.② At the left outflow-tract initial planes,reconstruction rates of all planes were above 75%,and there was no statistical difference(P=0.169).Each reconstruction plane had good score,even if the scores of longitudinal planes of the aortic arch/pulmonary artery were low,whose scores reached 1.936 and 2.051,respectively.③ At the initial longitudinal planes of the aortic arch,the reconstruction rate (96.67%) and average reconstruction score (2.617) of longitudinal planes of the pulmonary artery were obviously higher than those of other planes.④ Compared with different initial planes,volume data acquired from left outflow-tract initial planes could lead to high-quality reconstructed planes of all standard examination planes.While four-chamber initial planes acquired high-quality standard examination planes except longitudinal planes of the aortic arch and pulmonary artery.Volume data from initial longitudinal plane of the aortic arch acquired low-quality standard examination planes except longitudinal planes of the aortic arch and longitudinal plane of the pulmonary artery.Conclusions With STIC,sonographers can not only save the volume data for off-line analysis and remote consultation but also choose the better initial planes for themselves during the examination of fetal hearts.

The review is focused on the development and recent research of the first tissue-specific angiogenic molecule,endocrine gland-derived vascular endothelial growth factor(EG-VEGF).It has been found that EG-VEGF only targeted on steroidgenic endocrine organs or cells through G-protein coupled receptor,the phosphorylation of G-protein coupled receptor could activate mitogen-activated protein kinase p44/42 and phosphatidylinositol-3 kinase(PI3K) pathways signal transdution.There are many reports that believes MAPK and PI3K is involved in the regulation of proliferation,migration,survival of endothelial cells and tumor angiogenesis,so EG-VEGF may serve as a potential target for antiangiogenic therapy of cancer in the future.

OBJECTIVE:To improve automatic outpatient pharmacy drug delivery system in our hospital,and to promote the efficiency of automatic drug delivery. METHODS:The outpatient pharmacy automation system of our hospital was introduced in terms of main structure,working process and application. The work efficiency,safety and error were compared between automatic drug delivery mode and manual drug delivery mode. Drug delivery machine was improved to increase the rate of drug delivery. RE-SULTS:The outpatient pharmacy automation system of our hospital included 2 boxed drug delivery machine and 1 drug dispensing machine,etc. Compared with manual drug delivery mode,automatic drug delivery mode improved drug delivery efficiency,health security and use security,and reduced drug delivery error. Through adjusting the time setting and step of drug delivery of gearing in drug delivery machine,idle time of transmission equipment was utilized effectively,and the quantity of delivered prescriptions was increased,increasing from 220 to 320 each hour. CONCLUSIONS:The reasonable improvement of outpatient pharmacy auto-mation system makes outpatient pharmacy automation system play a bigger role,and further optimize resources.

Objective To assess the stresses of fiber posts combined with auxiliary posts in anterior teeth with flared canals by three dimensional finite element method .Methods Nine 3D models of maxillary first incisors with flared canals restored by two post systems(porcelain pile ,fiber and auxiliary pile) divided into 5 groups were generated .By static loading method ,dental crowns cut 1/3 and middle 1/3 connection link five points into 135 angles by 100 N force loading .The major stress for the dentin and the e‐quivalent Von Mises stress for resin cement and post and core were calculated .Results Biggest tooth stress value of 111 .9 Mpa and the largest resin adhesive stress value 54 .6 Mpa had appeared in the use of a model of the quartz fiber post after repair ,ceramics pile repair model of pile nuclear stress value and the maximum was 48 .1 Mpa .Combining with one auxiliary post ,stress values re‐duced significantly in dentin ,in cement and in post and core .However ,as more auxiliary posts were added ,the stresses did not de‐crease sequentially .Conclusion It is suggested that to restore the tooth with flared canals by quartz fiber post combining with one auxiliary post .

Immunohistochemical study revealed the distributions of substance P, neurokinin A, neurokinin B and calcitonin gene related peptide immunoreactive nerve fibers in the medulla, cortex and capsule of tracheobronchial lymph nodes in 10 guinea pigs. More immunopositive fibers were found to be distributed in the area around the blood vessels and lymph sinuses, less in the area distant to blood vessels. The four kinds of positive immunoreactive nerve fibers were also seen within the wall of the blood vessels. The results provide some morphological basis for the study of neuroimmunomodulation.

Pharmacological activities of the effective constituents: essential oils, flavonoids andalkaloids, in fruit of Citrus aurantium L. were compared. Blood pressure was increased markedly by transfusion of the alkaloids. Contractions of isolated intestines were iuhibited byflavonoids. Essential oils significantly decreased the rate and frequency of writhing syndromeinduced by ip acetie acid and spontaneous locomotor activities in the mice with the exceptionfexciting at first followed by inhibiting the isolated intestines,which displayed analgesia andoceutral inhibition to a certain extent.