7 cases of acute gastric Anisakiasis have been reviewed at the Department of Internal Medicine, Yeungnam University Hospital from March, 1983 to December 1986. 1. Of 7 cases, the ratio of male and female was 3:4 and the age 30s occupied most (5 cases) the 50s' followed (2 cases). 2. Chief complains were in order of epigastric pain (6 cases), vomiting (3 cases), Nause (2 cases), Ulticaria (1 case) & epigastric fulling sensation (1 case). 3. In all 7 cases, the causative fish in astroconcer myriaster. 4. The onset of symptoms was observed within 5 to 7 hours after eating the causative raw fish. 5. Gastrofiberscopic exam was undergo within 48 hours since onset of symptoms. 6. The gastrofiberscopic findings were gastric mucosal edema and redness in all 7 cases. One case also had mucosal erosion. The involved sites of the stomach were in frequency of order, the body (5 cases), the antrum (2 cases). 7. The symptoms of the patients relieved spontaneously without medical treatment after the extraction of the larva with biopsy forcep during gastrofiberscopy. 8. In Korea, many people take raw fish and there may be many patients of Anisakiasis so if much concern and careful observation are paid to whom with severe cramping epigastric pain after taking of raw marine fish in about 10 hours, we could find out and confirm more patients suffering from Anisakiasis by immediate endoscopic gastrofiberscopy.
Anisakiasis* ; Biopsy ; Eating ; Edema ; Female ; Humans ; Internal Medicine ; Korea ; Larva ; Male ; Muscle Cramp ; Sensation ; Stomach ; Surgical Instruments ; Vomiting

To improve and keep the competitiveness, it is necessary to keep pace with available changes in technology, and it is essential to establish the flexible and accurate information system about the disease. And for the accurate decision-making, target setting and prediction of movement, the estimating of the short- and long-term effects of the strategies of disease related service are required. But the limited informations, including all of knowledge of leprosy, make it difficult to estimate them properly. To achieve the more effective leprosy related service, we have to make the effort to crate the more accurate system. To proffer the idea for the development of information monitoring, we present the reviews of some articles about the information theories that used the leprosy related service.
Information Systems ; Information Theory ; Leprosy*

Of all the complications of Hansen's disease that remain after the disease is arrested, and that prevent a return to normal well-beinglife, the destruction of the feet by foot ulcer is one of the commonest and most crippling, and is the one that can be prevented if early care & well treatment are taken. So many leprologists are interesting in the treatment of foot ulcer. Despite numerous advances, foot ulcers in Hansen's disease continue to be a treatment challenge. Recently a new subatmospheric pressure technique: vacuum assisted closure treatments of it are introduced. It entails placing an open-cell foam dressing into the wound cavity and applying a controlled subatmospheric pressure. Thirty nine foot ulcers were treated. About 74.4% of all were showed good results. The authors are reviewed & summarized about the results of the newly presenting treatment, vacuum assisted closure, of foot ulcers.
Bandages ; Foot Ulcer* ; Foot* ; Leprosy* ; Negative-Pressure Wound Therapy* ; Wounds and Injuries

Though the early detection of leprosy is very important, it has been difficult to determine the M. leprae transmission in the community partly due to a lack of easy specific tools to measure it. A development of a seroepidemiological tool based on the phenolic glycolipid I(PGL-I), an M. leprae-specific antigen, made it possible to detect the M. leprae infection or exposure to the organism. In Korea, 11 studies, used it, were reported in the Korean Leprosy Bulletin. For the reduction of bias, we performed the integrated study of past 11 studies. In our study, we tried to find the useful values of the results of PGL-I Antibody IgM ELISA test for the control of leprosy and to know the further study for more valuable results.
Bias (Epidemiology) ; Enzyme-Linked Immunosorbent Assay* ; Immunoglobulin M* ; Korea ; Leprosy* ; Phenol

Loop-mediated isothermal amplification (LAMP) is a novel nucleic acid amplification method that amplifies DNA with high specificity, efficiency, and speed under isothermal conditions. To evaluate the usefulness of LAMP for diagnosing leprosy, we compared the results of LAMP method and PCR, using samples that were previously tested by PCR. We used the species-specific primers designed by targeting the 18KDa antigenic protein gene for the LAMP and PCR, for detection of Mycobacterium leprae directly from biopsy samples of patients. Doing LAMP and PCR, when the results of PCR ware regarded as standard, we observed the results of LAMP were equal to those of PCR. So we are thought the LAMP method is rapid, taking only 1 h, compared with about 4 h for PCR. In addition, it is performed under isothermal conditions and no special apparatus is needed, which makes it more economical and practical than PCR. Although further improvement is necessary for the wide spread use, the LAMP method might be applicable to diagnosis of leprosy.
Biopsy ; Diagnosis* ; DNA ; Humans ; Leprosy* ; Mycobacterium leprae* ; Mycobacterium* ; Polymerase Chain Reaction* ; Sensitivity and Specificity

Studies about Mycobacterium leprae DNA in samples from leprosy patients are included in the diagnosis of leprosy, the study of drug resistance and the epidemiological investigation. Recently, application of the polymerase chain reaction to epidemiological study of leprosy is introduced. PCR-based typing would be of great value for epidemiological investigation; to identify infectious source of leprosy, understand transmission pattern, and distinguish between relapse & re-infection. Variable TTC DNA repeats in non-coding region and 6bp(ACATCG) tandem repeats in rpoT gene revealed PCR products of different size may be useful to investigate the epidemiology of leprosy.
Diagnosis ; DNA ; Drug Resistance ; Epidemiologic Studies ; Epidemiology ; Humans ; Leprosy* ; Mycobacterium leprae ; Polymerase Chain Reaction* ; Recurrence ; Tandem Repeat Sequences

Many futurists state that the rate of change that has happened around the world over the past 10 years is greater than at all other period's of time. The leading factor, irrelevant of an individuals knowledge, is the popularization of the Internet. People now can get large amounts of information at a very low cost. Popularization of information technology has changed the economic competitiveness from existing physical production capacity to information collecting and information processing power. . In other words, advanced products that have high added value, generated by collecting and processing technical information, are superior to products that are made physically. With respect to Hansen's disease, after MDT was introduced in 1980's, and WHO started to eliminate leprosy in 1991, Hansen's disease situation has changed in most of the world. However, using only the traditional information systems that were used in the past, it is difficult to cope with this situation. To improve and keep the competitiveness, it is necessary to keep pace with available changes in technology, and it is essential to establish flexible information system about the disease. To do this, we have to create new services. To create a new paradigm for dealing properly with changes in the management of Hansen's disease in the information society, I would like to introduce an information system. As part of the development of this system, I would like to introduce new material resources including an information system, human resources, databases, and network.
Automatic Data Processing ; Humans ; Information Systems* ; Internet ; Leprosy*

Recently it is becoming socially controversy about Hansen's disease patient's registration system that was considered as the reasonable and best system in the past. Medically, it is naturally to make the patient's medical record(medial registration), including patient's detail profile, patient's family history, or other informations acquired form medical examination process for the clinical judgement and the best result of treatment. And that is necessary to government authorities that made the budget to provide the free medical and social service to Hansen's disease patients, but that is worry about the drain of personal information and the use of basic data to control. Therefore, we have to need to do enough examination between patient with leprologist, sociologist, government authorities and patients about this and advance this by reasonable system to everybody.
Budgets ; Humans ; Leprosy* ; Social Work

For the integrated leprosy control, including the elimination of leprosy and the leprosy related activity, the collection and analysis of the accurate data is essential. In Korea, we have applied the computerized information system of the leprosy control. This system was designed for data collection as well as data analysis. The major functions of this system include data entry, data transfer, from local level to central level, data sum-up, and production of information, including epidemiologial and clinical information and information for decision-making. Firstly we used this system for treatment workload only. Because the basic concept of our system's data structure is more flexible than other's, we try that we can use it more widely, for the leprosy related activity now. We think that this system has been supported effectively our integrated leprosy control work in Korea. We therefore present the computerized leprosy information system of Korea.
Data Collection ; Information Systems* ; Korea ; Leprosy* ; Statistics as Topic

Of all the complication of Hansen's disease that remain after the disease is arrested, and that prevent a return to normal well-being- life, the destruction of the feet by foot ulcer is one of the commonest and most crippling, and is one that can be prevented if early care & well treatment are taken. So many leprologists are interesting in the treatment of foot ulcer. Recently various treatments of it are introduced. The authors are reviewed & summarized about the newly presenting treatment of foot ulcer.
Foot Ulcer* ; Foot* ; Leprosy*