1.Two Case of Peripartum Cardiomyopathy.
In Soo LEE ; Jae Nam MA ; Yeoung Chan PARK ; Kyung Weon LEE ; Jong Cheon WEON ; Yong Pil KIM
Korean Journal of Obstetrics and Gynecology 1999;42(3):664-668
Peripartum cardiomyopathy is defined as a syndrome of cardiac failure occurring in tbe latter part of pregnancy or in the puerperium, without obvious cause and without prior evidence of heart disease. Despite its infrequency, this clinical problem may have devastating consequences upon maternal and fetal outcome. It is important to recognize the association of cardiac failure and pregnancy as a separate syndrome so that, once identified, peripartum cardiomyopathy can be treated promptly and aggressively. We experienced two cases of peripartum cardiomyopathy, and report these cases with a brief review of the literatures.
Cardiomyopathies*
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Heart Diseases
;
Heart Failure
;
Peripartum Period*
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Postpartum Period
;
Pregnancy
2.Clinical Analysis of 149 Cases of Twin Pregnancies.
Yeoung Chan PARK ; Sun Hee KO ; Tae In LEE ; Jae Nam MA ; Kang Woo JUNG ; Jong Cheon WEON ; Yong Pil KIM
Korean Journal of Obstetrics and Gynecology 2000;43(9):1539-1543
No abstract available.
Humans
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Pregnancy, Twin*
4.A Case of Nasal Septal Perforation Due to Alkaline Disc Battery as a Nasal Foreign Body.
Ki Sang RHA ; Weon Jo CHOI ; Pil Jun KO ; Chan Il PARK
Korean Journal of Otolaryngology - Head and Neck Surgery 1997;40(2):300-303
Due to the common use of alkaline disc batteries(e.g. watches, electronic toys and games, calculators, cameras) physicians and the general public should be more aware of this battery foreign body and the peculiarities in their management. Alkaline disc batteries as foreign bodies in the nasal cavities are extremely rare but dangerous because they can cause liquefaction necrosis with subsequent severe local tissue destruction. Batteries found in the nasal cavities should be removed immediately to prevent sequelae such as septal perforations or nasal stenosis. We recently experienced a case of 4-year-old boy who revealed necrotic perforation of nasal septum which was exposed directly to a alkaline disc battery for 20 hours and the special aspects of these foreign body is discussed.
Child, Preschool
;
Constriction, Pathologic
;
Foreign Bodies*
;
Humans
;
Male
;
Nasal Cavity
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Nasal Septal Perforation*
;
Nasal Septum
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Necrosis
;
Play and Playthings
5.The Clinical Outcomes of Coronary Stenting and Coronary Artery Bypass Grafting in ESRD Patients with Ischemic Heart Disease.
Joon Seung YI ; Jai Weon CHANG ; Mee Sook LEE ; Sang Pil CHANG ; Seong Wook PARK ; Cheol Whan LEE ; Hyun SONG ; Jung Sik PARK
Korean Journal of Nephrology 2001;20(2):250-257
The purpose of this study was firstly, to evaluate the efficacy of coronary stenting in ESRD patients compared with non uremic patients and secondly, to compare the perioperative mortality of coronary artery bypass grafting(CABG) in ESRD patients with that in non-uremic patients exhibiting a similar degree of left ventricular function. We examined the clinical restenosis of coronary stenting and 30 day mortality rate after CABG in this retrospective, case-controlled study. The case histories of twenty-five ESRD patients with ischemic heart disease(IHD) and twenty-five non-uremic IHD patients matched for age, sex, ejection fraction and number of implanted stents, who had undergone first, elective, primarily successful coronary stenting were reviewed. The case of histories of another sixteen ESRD patients with IHD and sixteen non-uremic IHD patients matched for age, sex, ejection fraction and number of grafted vessels, who had undergone first elective CABG were also reviewed. Clinical restenosis developed in nine of the twenty-five ESRD patients and in eight of the twenty-five non-uremic patients after coronary stenting within follow up periods of 16.9+/-14.5 months and 17.6+/-14.6 months, respectively. There was no significant difference in the cumulative clinical restenosis free curves between the two groups(p=0.79). Three out of sixteen for the ESRD patients and one out of sixteen for the non-uremic patients died in 30 days after CABG, follow up periods being 11.3+/-9.6 months and 11.1+/-8.9 months, respectively. The perioperative mortality did not differ between the two groups(p=0.28). We conclude that coronary stenting in ESRD patients is as effective as in non-uremic patients regarding initial coronary revascularization and perioperative mortality rate of CABG in ESRD patients is not significantly higher compared with non-uremic patients when Left ventricular function is matched.
Case-Control Studies
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Coronary Artery Bypass*
;
Coronary Vessels*
;
Follow-Up Studies
;
Heart
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Humans
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Kidney Failure, Chronic
;
Mortality
;
Myocardial Ischemia*
;
Retrospective Studies
;
Stents*
;
Transplants
;
Ventricular Function, Left
6.Comparison of left ventricular hypertrophy between hypertensives and chronic renal disease patients: Echocardiographic Study.
Dong Il KIM ; Jong Hoon SONG ; Sang Wook IM ; Sung Gon PARK ; En Mee CHUNG ; Dong Hoon CHA ; Pil Weon PARK ; Jae Hyung AHN
Korean Journal of Medicine 1998;55(6):1005-1021
OBJECTIVES: Left ventricular hypertrophy (LVH) is one of the most common echocardiographic findings and an important prognostic factor for cardiovascular mortality in hypertensives and chronic renal failure patients. To evaluate the prevalence and the types of LVH, and left ventricular systolic and diastolic functions as worsening of renal function, and to elucidate the risk factors for LVH, we performed this study retrospectively in normal populations, hypertensives, and renal failure with or without hemodialysis. METHODS AND SUBJECTS: We recruited the study population among the patients who had taken echocardiography at Pun-Dang CHA Hospital from July, 1995 to June, 1997. They are consisted of 54 patients for normal control, 53 patients of hypertensives, 31 patients of mild renal failure with less than 4.5 mg/dl of serum creatinine (Group I), 29 patients of moderate renal failure with more than 4.5 mg/dl of serum creatinine (Group II), and 47 patients of end stage renal disease with hemodialysis (Group III). The echocardiography was performed with all standard strategies including 2 dimension, M mode, and Doppler signals. RESULTS: 1) Among the baseline characteristics, the body mass index only significantly increased in hypertensives compared with group II and III.2) The prevalences of LVH in each groups were 5.6% in control group, 49.1% in hypertensives, 83.8% in group I, 89.7% in group II, and 100% in group III respectively. And the pevalences of concentric LVH were 5.6%, 43.3%, 41.9%, 34.5%, and 25.5% and those of the eccentric hypertrophy were 0.0%, 5.7%, 41.9%, 55.2%, and 74.5% respectively. The prevalence of eccentric hypertrophy increased according to deterioration of renal function.3) The left ventricular mass index was significantly higher in hypertensives, Group I, Group II, and Group III than normal control and the left ventricular volume index was greater in all renal failure patients compared with controls and hypertensives.4) In pre-hemodialysis renal failure patients, the types of LVH were consisted of 8 of normal heart (Group A), 23 of concentric LVH (Group B), and 29 of eccentric LVH (Group C). The systolic blood pressure and mean arterial pressure were significantly higher in group C than group A but there was no significant difference between group C and B. The RBC volume was significantly decreased in group B and C compared with group A. The echocardiographic end diastolic interventricular septal thickness and posterior wall thickness were significantly thicker in group B than others but end diastolic LV dimension, LV mass index, and LV volume index were significantly increased in group C than group B and A. The LV ejection fraction and fractional shortening as markers of LV systolic function in group C revealed the lowest level among three groups. The E velocity among the Doppler study profiles was significantly higher in group C than others.5) In hemodialysis group, all the patients had any types of LV hypertrophic changes. The concentric LVH group (group B) had significantly higher systolic blood pressure and mean arterial pressure than eccentric LVH (group C) but there was no difference in diastolic blood pressure between two groups. The echocardiographic interventricular septum and posterior wall were thicker in group B than group C but end diastolic LV dimension and LV volume were significantly higher in group C than group B.6) The LV mass index in pre-hemodialysis group had positive relationship with blood pressure and serum urea nitrogen level and the LV volume index was positively correlated with systolic blood pressure and mean blood pressure.7) The LV mass index in hemodialysis group had positive relationship with age and systolic blood pressure and LV volume index was positively correlated with serum urea nitrogen level but negatively correlated with blood pressure. CONCLUSION: The prevalence of LVH was much higher in renal failure group than hypertenssives and the proportion of eccentric LVH was increased with worsening of renal function. Although the arterial hypertension is the most important risk factor for LVH, this finding suggested existence of other contributing risk factors for LVH in chronic renal failure, which included uremia, anemia, and age.
Anemia
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Arterial Pressure
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Blood Pressure
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Body Mass Index
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Creatinine
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Echocardiography*
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Heart
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Humans
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Hypertension
;
Hypertrophy
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Hypertrophy, Left Ventricular*
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Kidney Failure, Chronic
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Mortality
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Nitrogen
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Prevalence
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Renal Dialysis
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Renal Insufficiency
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Renal Insufficiency, Chronic*
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Retrospective Studies
;
Risk Factors
;
Urea
;
Uremia
7.A Case of Bilateral Lung Volume Reduction Surgery in Severe Emphysema.
Nam Young KANG ; Jae Seuk PARK ; Myeung In LEE ; Dong Yeol HA ; Young Koo JEE ; Kye Young LEE ; Keun Yeol KIM ; Pil Weon SEO
Tuberculosis and Respiratory Diseases 1998;45(3):630-635
Lung volume reduction surgery, resecting the most severely affected regions of emphysema, was designed to improve quality of life for selected patients with severe emphysema. We report a case of a 72 year old severe emphysema patient who received bilateral lung volume reduction surgery and showed marked improvement of quality of life and lung function.
Aged
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Emphysema*
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Humans
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Lung*
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Pneumonectomy*
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Quality of Life
8.Acute respiratory distress syndrome associated with scrub typhus: diffuse alveolar damage without pulmonary vasculitis.
Jae Seuk PARK ; Young Koo JEE ; Kye Young LEE ; Keun Yeol KIM ; Na Hye MYONG ; Pil Weon SEO
Journal of Korean Medical Science 2000;15(3):343-345
Pathologic findings of scrub typhus have been characterized by vasculitis of the microvasculature of the involved organ resulting from a direct invasion by Orientia tsutsugamushi. We experienced a case of acute respiratory distress syndrome (ARDS) associated with scrub typhus. The case was proven by eschar and high titer of serum IgM antibody (positive at 1:1280). Open lung biopsy showed diffuse alveolar damage (DAD) in the organizing stage without evidence of vasculitis. Immunofluorescent antibody staining and polymerase chain reaction for O. tsutsugamushi failed to demonstrate the organism in the lung tissue. The patient expired due to progressive respiratory failure despite doxycycline therapy. Immunologic mechanism, without direct invasion of the organism, may participate in the pathogenesis of ARDS associated with scrub typhus.
Acute Disease
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Aged
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Case Report
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Fatal Outcome
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Female
;
Human
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Infant, Newborn
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Pulmonary Alveoli/pathology
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Pulmonary Alveoli/injuries
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Respiratory Distress Syndrome/physiopathology
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Respiratory Distress Syndrome/pathology
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Respiratory Distress Syndrome/immunology
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Respiratory Distress Syndrome/complications*
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Scrub Typhus/physiopathology
;
Scrub Typhus/pathology
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Scrub Typhus/immunology
;
Scrub Typhus/complications*
;
Vasculitis
9.The difference of detection rate of avian influenza virus in the wild bird surveillance using various methods
Gang San KIM ; Tae Sik KIM ; Joo Sung SON ; Van Dam LAI ; Jung Eun PARK ; Seung Jun WANG ; Weon Hwa JHEONG ; In Pil MO
Journal of Veterinary Science 2019;20(5):e56-
Korea is located within the East Asian-Australian flyway of wild migratory birds during the fall and winter seasons. Consequently, the likelihood of introduction of numerous subtypes and pathotypes of the Avian influenza (AI) virus to Korea has been thought to be very high. In the current study, we surveyed wild bird feces for the presence of AI virus that had been introduced to Korea between September 2017 and February 2018. To identify and characterize the AI virus, we employed commonly used methods, namely, virus isolation (VI) via egg inoculation, real-time reverse transcription-polymerase chain reaction (rRT-PCR), conventional RT-PCR (cRT-PCR) and a newly developed next generation sequencing (NGS) approach. In this study, 124 out of 11,145 fresh samples of wild migratory birds tested were rRT-PCR positive; only 52.0% of VI positive samples were determined as positive by rRT-PCR from fecal supernatant. Fifty AI virus specimens were isolated from fresh fecal samples and typed. The cRT-PCR subtyping results mostly coincided with the NGS results, although NGS detected the presence of 11 HA genes and four NA genes that were not detected by cRT-PCR. NGS analysis confirmed that 12% of the identified viruses were mixed-subtypes which were not detected by cRT-PCR. Prevention of the occurrence of AI virus requires a workflow for rapid and accurate virus detection and verification. However, conventional methods of detection have some limitations. Therefore, different methods should be combined for optimal surveillance, and further studies are needed in aspect of the introduction and application of new methods such as NGS.
Animals
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Birds
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Feces
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Influenza in Birds
;
Korea
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Methods
;
Ovum
;
Seasons
10.The Poisoning Information Database Covers a Large Proportion of Real Poisoning Cases in Korea.
Su Jin KIM ; Sung Phil CHUNG ; Hyo Wook GIL ; Sang Cheon CHOI ; Hyun KIM ; Changwoo KANG ; Hyun Jin KIM ; Jung Soo PARK ; Kyung Woo LEE ; Junho CHO ; Jae Chol YOON ; Soohyung CHO ; Michael Sung Pil CHOE ; Tae Sik HWANG ; Dae Young HONG ; Hoon LIM ; Yang Weon KIM ; Seung Whan KIM ; Hyunggoo KANG ; Woo Jeong KIM
Journal of Korean Medical Science 2016;31(7):1037-1041
The poisoning information database (PIDB) provides clinical toxicological information on commonly encountered toxic substances in Korea. The aim of this study was to estimate the coverage rate of the PIDB by comparing the database with the distribution of toxic substances that real poisoning patients presented to 20 emergency departments. Development of the PIDB started in 2007, and the number of toxic substances increased annually from 50 to 470 substances in 2014. We retrospectively reviewed the medical records of patients with toxic exposure who visited 20 emergency departments in Korea from January to December 2013. Identified toxic substances were classified as prescription drug, agricultural chemical, household product, animal or plant, herbal drug, or other. We calculated the coverage rate of the PIDB for both the number of poisoning cases and the kinds of toxic substances. A total of 10,887 cases of intoxication among 8,145 patients was collected. The 470 substances registered in the PIDB covered 89.3% of 8,891 identified cases related to poisoning, while the same substances only covered 45.3% of the 671 kinds of identified toxic substances. According to category, 211 prescription drugs, 58 agricultural chemicals, 28 household products, and 32 animals or plants were not covered by the PIDB. This study suggested that the PIDB covered a large proportion of real poisoning cases in Korea. However, the database should be continuously extended to provide information for even rare toxic substances.
Adolescent
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Adult
;
Aged
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Animals
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Animals, Poisonous
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Child
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Child, Preschool
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Databases, Factual
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Drugs, Chinese Herbal/poisoning
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Emergency Service, Hospital
;
Female
;
Humans
;
Infant
;
Male
;
Middle Aged
;
Pesticides/poisoning
;
Plants, Medicinal/poisoning
;
Poisoning/*epidemiology
;
Prescription Drugs/poisoning
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Republic of Korea
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Retrospective Studies
;
Young Adult