2.A Statistical Study for Diagnostic Accuracy of Ultrasonography of Subcutaneous Nodules.
Yoon Hwan KIM ; Seung Jae LEE ; Ji Hye PARK ; Chong Won CHOI ; Ga Young LEE ; Won Serk KIM
Korean Journal of Dermatology 2013;51(6):415-421
BACKGROUND: Ultrasonography is an important diagnostic tool for many aspects of clinical medicine. It is a non-invasive method of examination that provides high-resolution images in real time. However, some dermatologists may be anxious about the efficacy of ultrasonography. OBJECTIVE: To evaluate the diagnostic accuracy and to assess the utility of diagnostic ultrasonography for subcutaneous benign lesions. METHODS: The study included 96 patients with subcutaneous benign lesions who underwent ultrasonography and then received a pathologic diagnosis after biopsy or surgery at our hospital from July 2010 to December 2012. This study evaluated the number of cases in which the preoperative diagnosis after ultrasonography or just after physical examination agreed to the pathologic diagnosis. RESULTS: Ultrasonography significantly increased the diagnostic yield of subcutaneous benign lesions (after physical examination, 54.2%; after ultrasonography, 84.4%; p<0.001). The sensitivity for the diagnosis of lipoma (after physical examination, 70%; after ultrasonography, 92.5%; p<0.001) and the specificity for the diagnosis of epidermal cyst (after physical examination, 84.1%; after ultrasonography, 94.2%; p<0.001) significantly increased after ultrasonography. The sensitivity for the diagnosis of epidermal cyst and pilomatricoma also tended to increase after ultrasonography. CONCLUSION: The study results suggested that ultrasonography is useful for diagnosis and/or preoperative examination of subcutaneous benign lesions.
Biopsy
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Clinical Medicine
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Epidermal Cyst
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Humans
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Lipoma
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Physical Examination
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Pilomatrixoma
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Sensitivity and Specificity
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Statistics as Topic
5.The Diagnostic Value of Positron Emission Tomography in Detecting the Breast Cancer.
Dong Young NOH ; Ik Jin YUN ; Han Sung KANG ; Ji Soo KIM ; Dong Soo LEE ; June Key CHUNG ; Myung Chul LEE ; Yeo Kyu YOUN ; Seung Keun OH ; Kuk Jin CHOE
Journal of Korean Breast Cancer Society 1998;1(1):6-12
Positron Emission Tomography (PET) is a new imaging method employing radionuclide and tomography technique. In breast cancer PET has high sensitivity in detecting primary tumor and axillary node metastasis. From 1995 June to 1996 November, 27 patients had undergone breast operations following PET under impression of breast cancer in Seoul National University Hospital (SNUH). Whole body PET images were obtained beginning 60 minutes after infection of 370 MBq (10 mCi) F-18 FDG (fluorodeoxy glucose). Regional scans were also obtained with transmission images. We compared PET results with those of physical examination and mammography. All cases were histologically confirmed. For primary tumor mass, diagnostic accuracy of PET was excellent (97%) compared with the physical examination (78%) and mammography (67%). For axillary lymph node metastasis, PET had an outstanding detection accuracy (96%), compared with the physical examination and mammography (74%, 60%, respectively). And whole body PET scan made it possible to see the all metastatic lesions at a glance in cases of metastatic or recurred breast cancer. There was likely correlation between Standard Uptake Value (SUV) and the number of axillary lymph node metastasis, but in this study, statistical significance was not proven because of small number of cases. PET also could detect breast cancer in paraffin augmented breast. We concluded that PET is very sensitive and accurate diagnostic tool for breast cancer and SUV, after more studies, could be used as an important prognostic factor.
Breast Neoplasms*
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Breast*
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Electrons*
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Humans
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Lymph Nodes
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Mammography
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Neoplasm Metastasis
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Paraffin
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Physical Examination
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Positron-Emission Tomography*
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Prognosis
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Seoul
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Statistics as Topic
6.Vertebral and Intraspinal Anomalies in Indian Population with Congenital Scoliosis: A Study of 119 Consecutive Patients.
Neeraj GUPTA ; Rajasekaran S ; Balamurali G ; Ajoy SHETTY
Asian Spine Journal 2016;10(2):276-281
STUDY DESIGN: Retrospective case study by clinical and radiological data analysis. PURPOSE: To analyze different types of vertebral anomalies and the incidence of associated intraspinal anomalies in the Indian population. OVERVIEW OF LITERATURE: This is the largest study of congenital scoliosis and associated intraspinal anomalies in Indian population. Incidence of intraspinal anomaly in this series is 47% which is higher than previous literature. Hemivertebra was the most common anomaly as seen in previous studies. METHODS: A total of 119 patients with congenital scoliosis who underwent surgery between December 2006 and December 2012 were studied. Data was reviewed with medical records, plain radiographs, and magnetic resonance imaging (MRI) scans. RESULTS: Thoracolumbar curve was most common, seen in 43.6% of patients. In addition to scoliotic deformity, kyphosis was seen in 26% of patients. Failure of formation, the most common vertebral anomaly, was seen in 51.2% of patients, failure of segmentation was seen in 19.3% of patients, and there were 29.4% patients having both formation and segmentation anomalies. Hemivertebra was the most common vertebral anomaly seen in 66.3% of patients and for whom 63.2% were in thoracic spine. Intraspinal anomalies were associated with 47% of patients with congenital scoliosis. Tethered cord was the most common intraspinal abnormality and was found in 48.2% patients with intraspinal anomalies. The patients with failure of segmentation and mixed deformities were found to have a significantly higher incidence of intraspinal anomalies (65% and 57%, respectively) than those with failure of formation (34%). Out of 31 patients with kyphotic deformity 29% had intraspinal anomalies, and amongst them tethered cord was the most common anomaly seen in 66% patients. Out of 12 patients with neurocutaneous markers, 83% patients had intraspinal anomaly. CONCLUSIONS: Intraspinal anomalies were seen in 47% of patients with congenital scoliosis in the Indian population. Tethered cord was the most common intraspinal anomaly, seen in 48% cases of congenital scoliosis. Hemivertebra was seen in 66% cases and was the most common vertebral defect. Hence MRI imaging of whole spine should be done in all cases of congenital scoliosis before any surgical intervention. Special attention should be given to physical examination and visualization of any neurocutaneous markers, which are associated with a higher incidence of intraspinal anomalies; absence of a neurocutaneous marker, however, does not rule out intraspinal anomaly.
Congenital Abnormalities
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Humans
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Incidence
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Kyphosis
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Magnetic Resonance Imaging
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Medical Records
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Physical Examination
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Retrospective Studies
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Scoliosis*
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Spine
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Statistics as Topic
9.A Preliminary Study on Musculoskeletal Pain in K-League Referees: A Complete Survey.
The Korean Journal of Sports Medicine 2014;32(1):37-43
The environment around working process of the referees during matches will burden him or her physically by doing specific actions frequently and give negative effects on musculoskeletal system. In order to find out musculoskeletal pain has occurred on specific muscles, surveys have been taken by 44 referees in K-league for this thesis. We evaluated the differences between referee and assistant referee. Fourteen (87.5%) referees and twenty-four (89.3%) assistant referees stated that they had one musculoskeletal pain. For referees, 43.8% had hamstring pains, 31.3% had calf muscle pains, and 25% had low back pains. For assistant referees, 39.3% felt knee pains, 32.1% had adductors pains, 28.5% felt calf muscle pains. Therefore, with the data analysis by dividing their roles, both groups had similar effect on hamstring and knee joint. For the question asking for the personal reasons of the pains were 61.4% of 'Carelessness of physical fitness', 47.7% of 'repetition of certain actions', and 43.2% of 'lack of treatment after being damaged'. Also, in order to prevent pain, the referees answered that they train personally (40.9%), rest appropriately (20.5%), and go to hospital for treatment (18.2%). After receiving the result of this study, training programs and education are needed to prevent pain. Moreover, on the next study, fundamental causes of the pains should be found by using history taking, physical examination, medical and scientific machines in order to analyze the movements of the referees' human dynamics.
Education
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Football
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Humans
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Knee
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Knee Joint
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Low Back Pain
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Muscles
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Musculoskeletal Pain*
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Musculoskeletal System
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Myalgia
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Physical Examination
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Statistics as Topic
10.Association between serum adiponectin and mean blood pressure.
Xin-Li LI ; Min TONG ; Qiong XU ; Xin-Zheng LU ; Zhen-Zhen WANG ; Yan-Li ZHOU ; Hai-Feng ZHANG ; Ke-Jiang CAO ; Jun HUANG
Chinese Journal of Cardiology 2007;35(4):320-324
OBJECTIVETo investigate the relationship between serum adiponectin and mean blood pressure (BP).
METHODSA total of 187 subjects were divided into four groups according to BP levels: optimal blood pressure group (n = 38), high normal blood pressure group (n = 50), treated hypertension group (n = 54) and untreated hypertension group (n = 45). Serum adiponectin and microalbuminuria were detected by radioimmunology assay. Insulin resistant index defined as HOMA-IR and urinary concentration of microalbuminuria/urinary concentration of creatinine defined as albumin creatinine ratio (ACR) were calculated.
RESULTS(1) Serum adiponectin decreased in proportion to BP increase and the serum adiponectin level was significantly higher in treated hypertension group than untreated hypertension group. (2) Correlation analysis showed that adiponectin concentration was negatively correlated with mean blood pressure (P < 0.01). (3) Multivariate regression analysis revealed that mean blood pressure and HOMA-IR were independent predictors of serum adiponectin level.
CONCLUSIONSMean blood pressure was the main determinant of serum adiponectin level and negatively correlated to serum adiponectin level.
Adiponectin ; blood ; Adult ; Blood Pressure ; physiology ; Female ; Humans ; Insulin Resistance ; Male ; Middle Aged ; Physical Examination ; statistics & numerical data