1.Value of vaginal ultrasound in finding the endometrial cancer in the postmenopausal women with bleedin
Journal of Vietnamese Medicine 1999;233(2):39-46
Diagnostic curettage has for many years been the method of choice to diagnose endometrial cancer in women with postmenopausal bleeding. In fact, approximately only 10% in this group of women will be diagnosed with endometrial cancer. This study used endometrial thickness as measured by endovaginal ultrasonography as an indicator of endometrial abnormality. The histopathologic diagnosis obtained at curettage is used as the gold standard. 74 women were included in this study. Endometrial cancer was not found with the endometrium= 5 mm thick. The mean endometrial thickness in those women with endometrial cancer was 13.72+/- 8.09 mm compared with 4.3 +/- 2.3 mm in those women with benign endometrium. If the cut off limit for endometrial cancer and hyperplasia was 5 mm, the sensitivity was 100% the specificity was 71.2%, the positive predictive value was 60%, the negative predictive value was 100% and the Kappa ratio was 0.6%. If this limit had been used in this study, 70% of the curettage procedures could have been avoided.
Ultrasonography
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Endometrial Neoplasms
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women
2.Some remarks on simultaneous endometrioid carcinoma of the endometrium and ovary
Journal of Vietnamese Medicine 1999;232(1):114-117
Simultaneous endometrioid carcinoma of the endometrium and ovary was also called 'endometrioid systematic carcinoma'. This disease was not common with the rate of 5.2% of all endometrial carcinomas. This malignant epithelial neoplasm was presented with high differentiation (Grade 1), and it was often detected at early stages (0; 1A: 1B). Their common symptoms were abnormal metrorrhagia associating with ovarian cyst in young women having low parity. The determined diagnosis based on macroscopic and microscopic description, which could be a key significance in classification of this special lesion
Uterine Neoplasms
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Ovary
;
diagnosis
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Carcinoma, Endometrioid
3.The variations of the plasma hemoglobin concentration, electrolytes concentrations and the plasma LDH activity in the blood stored at the Central Blood Tranfusion and Hematology Institute
Journal of Practical Medicine 2004;487(9):61-62
This longitudinal prospective study was carried out on 6 blood samples of 6 male volunteers at National Institute of Hematology and Blood Transfusion to examine the changes biochemical parameters, shape of blood cells, and variations of all blood components during blood store. Results: plasma Hb and K+ concentrations and LDH activity in stored blood increased significantly; plasma Na+ and Cl concentrations decreased significantly along the time. These variations occurred in the first week of store. There were changes in the shape of red blood cells during blood store.
Blood
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Hemoglobins
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Plasma
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Electrolytes
4.Investigation of oral bacteria in Vietnam dental plaque
Journal of Vietnamese Medicine 2003;287(8):11-17
The samples of dental deposit plaque collected from 30 people in the faculty of Natural Science were stained by Gram technique. A bacterial prosperious component was detected including Gram (+) cocci, Gram (-) cocci, red and thin cell, red and long cell, straight and curved Gram (-) cells, thin spinal cells … Microorganism population on the deposit plaque under the gun includes bacteria, cocci, and spirochaetes. 3 genera were determined including Streptococcus, Lactobacillus and Actinomyces, with a highest incidence of Streptococcus. The representative genus has the characteristic similar to Streptococcus mutans and it seems that it plays an important role leading to caries
Dental Plaque
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Bacteria
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Dental Care
5.Polyphenolic component of fruit skin of Garcinia mangostana L. and inhibitory effect on acid production by Streptococcus mutans GS-5
Pharmaceutical Journal 2004;44(6):18-21
Which component of polyphenol of Garcinia mangostana L effecting on S. mutans GS-5 causing tooth decay was studied. The materials: the microorganism strain Streptococus mutans GS-5 of America. The method: compounds of polyphenol were isolated by thin layer chromatography method. To measure the pH reduction in glycolysis. The result: Using thin layer chromatography on silicagen was isolated 15 bands of flavonoid from the extract of mangostana. The flavonoid component corresponding with Rf 0,80; Rf 0,86 and Rf 0,91 can strongly inhibit the acid production of S.mutans GS-5
Pharmaceutical Preparations
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Flavonoids
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Streptococcus mutans
6.Apropos of one case of successful treating for ventrical fibrillation and cardiac arrest during performance of percutaneous transluminal coronary angioplasty and stenting in acute myocardial infarction patient
Journal of Practical Medicine 2005;510(4):79-81
Study on one case of ventrical fibrillation and cardiac arrest during performance of percutaneous transluminal coronary angioplasty (PTCA) and stenting in acute myocardial infarction patient at Central Military Hospital 108. Results: the complication of arrhythmia, ventrical fibrillation and cardiac arrest often occurred in patient with acute inferoposterior wall myocardial infarction. Stent-related complications included embolism, coronary piercing and hemorrhage. All equipment and drugs should be prepared when performing PTCA and stenting, especially patients with arrhythmia must be observed by ICU doctor. Electric defibrillation is the most effective treatment of ventrical fibrillation during PTCA and stenting. If CPR has been done correctly, the patient would fully recover although the time of asystole was more than 10 minutes.
Myocardial Infarction
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Angioplasty, Transluminal, Percutaneous Coronary
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Stents
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Therapeutics
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Heart Arrest
7.Chemical components of essential oil of Mentha piperita L. collected from Sapa – Lao Cai and now cultivated in Co Nhue, Tu Liem district – Ha Noi
Pharmaceutical Journal 2003;326(6):13-16
Mentha piperita L.Mentha piperita L. was collected from Sapa, Lao Cai province and cultivated at Co Nhue – Tu Liem – Ha Noi. The content of the essential oil in fresh branches of this peppermint was about 0.16%. Its green yield is 1.85-2.10 Kg/m2. First time in Vietnam, the chemical composition of peppermint oil was analyzed by GC/MS and 43 constituents were identified. The main constituents were L-menthol (47.60%), menthol (24.10%), menthofuran (6.07%) and 1.8 cineol (5.55%), pulegone (4.22%). Base on these data. The quality of Sa Pa peppermint oil is good as one from native origin. Peppermint collected from Sa Pa enrich the gene source of medicinal plant in general and particularly the gene source of essential oil plant group of Vietnam
Oils, Volatile
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Chemistry
;
Plants
8.The treatment of active chronic B hepatitis using lamivudine
Journal of Medical and Pharmaceutical Information 2004;0(7):28-31
This randomized, placebo-controlled clinical study evaluated the efficacy of lamivudine in 44 Vietnamese patients with histologically documented chronic hepatitis B for one-year. The patients were randomly assigned to receive 100 mg of lamivudine (22 patients) orally once daily or placebo (22 patients). The patients underwent liver biopsies before entering the study and after completing the assigned treatment regimen. At the end of therapy, the percentage of serum HBVDNA negativation was higher in the lamivudine group (86.4%) than in the control group (22% P<0.05). The rate of HBe/antiHBe seroconversion was statistically different between 2 groups (35.2% in the lamivudine group compared to 12.5% in the controls). 95.5% of the patients received lamivudine had normal alanine aminotransferase levels (versus 18.2% in the placebo). Median change in HAI score was >2 points of improvement versus placebo. Lamivudine is less side effects, safety, and favorable
Hepatitis B, Chronic
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Lamivudine
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Hepatitis B
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Therapeutics
;
drugs
9.Variation of essential oil content in Japanese Perpermin SK – 33 according to period of development and term of conservation
Pharmaceutical Journal 2003;322(2):26-28
This paper presented a study on the dynamic of essential oil accumulation in Japanese mint SK33 (M. arrvensis L.) and the influence of storage time on its quantity and quality. This mint was cultivated at Co Nhue experimental station, Tu Liem district, Ha Noi City between 2000 and 2002. The results showed that during the vegetation and development process, the essential oil content in the plant gradually increased and achieved maximum at first branch flowering stage and reduced to minimum at the end of flowering stage. The menthol content in essential oil of Japanese mint SK33 reached the highest value at full flowering stage (81.79%). The best harvest time for this mint is from the beginning flowering stage to full flowering period. After harvesting the whole plants can be stored during 20 days without the change in content and quality of essential oil
oils
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Conservation of Natural Resources
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Oils, Volatile
10.To study the variation of histological activity indices in chronic B hepatitis patients treated by limivudine
Journal of Practical Medicine 2003;425(5):27-28
44 patients of chronic B hepatitis are divided into two groups of 22 patients. The one is treated with lamivudine (Jefflix) 100 mg daily in 12 months continuously and the other with usual vitamin and liver tonics. Results showed in 72.7% patients of lamivudine group, the indices of histological activities were improved (through Knodell score), while in controlled group – 31.8% and over the half of this group these indices worsened. Thus, lamivudine has got good effect
Histological Techniques
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Hepatitis B
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Patients
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Lamivudine
;
drugs
;
Therapeutics