2.Reliability assessment and correlation analysis of evaluating orthodontic treatment outcome in Chinese patients.
Guang-Ying SONG ; Zhi-He ZHAO ; Yin DING ; Yu-Xing BAI ; Lin WANG ; Hong HE ; Gang SHEN ; Wei-Ran LI ; Sheldon BAUMRIND ; Zhi GENG ; Tian-Min XU
International Journal of Oral Science 2014;6(1):50-55
This study aimed to assess the reliability of experienced Chinese orthodontists in evaluating treatment outcome and to determine the correlations between three diagnostic information sources. Sixty-nine experienced Chinese orthodontic specialists each evaluated the outcome of orthodontic treatment of 108 Chinese patients. Three different information sources: study casts (SC), lateral cephalometric X-ray images (LX) and facial photographs (PH) were generated at the end of treatment for 108 patients selected randomly from six orthodontic treatment centers throughout China. Six different assessments of treatment outcome were made by each orthodontist using data from the three information sources separately and in combination. Each assessment included both ranking and grading for each patient. The rankings of each of the 69 judges for the 108 patients were correlated with the rankings of each of the other judges yielding 13 873 Spearman rs values, ranging from -0.08 to +0.85. Of these, 90% were greater than 0.4, showing moderate-to-high consistency among the 69 orthodontists. In the combined evaluations, study casts were the most significant predictive component (R(2)=0.86, P<0.000 1), while the inclusion of lateral cephalometric films and facial photographs also contributed to a more comprehensive assessment (R(2)=0.96, P<0.000 1). Grading scores for SC+LX and SC+PH were highly significantly correlated with those for SC+LX+PH (r(SC+LX)vs.(SC+LX+PH)=0.96, r(SC+PH)vs.(SC+LX+PH)=0.97), showing that either SC+LX or SC+PH is an excellent substitute for all three combined assessment.
Adolescent
;
Cephalometry
;
standards
;
China
;
Dental Models
;
standards
;
Esthetics, Dental
;
Female
;
Humans
;
Male
;
Malocclusion, Angle Class I
;
therapy
;
Malocclusion, Angle Class II
;
therapy
;
Malocclusion, Angle Class III
;
therapy
;
Orthodontics
;
standards
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Peer Review, Health Care
;
standards
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Photography
;
standards
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Reproducibility of Results
;
Treatment Outcome
3.A medical image color correction method based on supervised color constancy.
Jiatuo XU ; Liping TU ; Zhifeng ZHANG ; Changle ZHOU
Journal of Biomedical Engineering 2010;27(4):721-726
This paper presents a medical image acquisition and analysis method-TRM (Topology Resolve-Map) Model-under natural light condition indoors. Firstly, in accordance to medical image color characteristics, a colorful and grayscale color control patch was made for use as supervised color. "Topology Resolve-Map-Restoration" was carried on in LAB color space of the one-dimensional L* space and the two-dimensional a* b* space. Then, L* value was regulated by subsection regulation and a* b* value was regulated by triangulation topological cutting--close in on center of gravity method. After correction of the 198 color blocks in 22 pictures, the results showed that, by comparison with the standard value, the deltaL*, deltaC* and deltaE decreased significantly (P < 0.01) after correction by TRM. After correction, the difference in image's color is reduced, the color saturation is improved and the value is closer to true value. TRM model can significantly reduce the color difference of the medical image under natural light condition; it has a good effect on color correction.
Artificial Intelligence
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Calibration
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Color
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standards
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Humans
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Image Processing, Computer-Assisted
;
methods
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Pattern Recognition, Automated
;
methods
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Photography
;
instrumentation
;
methods
4.Using ImageJ to Evaluate Optic Disc Pallor in Traumatic Optic Neuropathy.
Sunah KANG ; Ungsoo Samuel KIM
Korean Journal of Ophthalmology 2014;28(2):164-169
PURPOSE: To evaluate optic disc pallor using ImageJ in traumatic optic neuropathy (TON). METHODS: This study examined unilateral TON patients. The optic disc was divided into 4 quadrants (temporal, superior, nasal, and inferior), consistent with the quadrants on optical coherence tomography (OCT) retinal nerve fiber layer (RNFL) thickness maps. Optic disc photography was performed and disc pallor was quantified using gray scale photographic images imported into ImageJ software. The correlation between optic disc pallor and RNFL thickness was examined in each quadrant. RESULTS: A total of 35 patients (31 male, 4 female) were enrolled in the study. The mean participant age was 34.8 +/- 15.0 years (range, 5 to 63 years). Overall RNFL thickness decreased in 6 patients, with thinning most often occurring in the inferior quadrant (28 of 35 eyes). There was a significant correlation between optic disc pallor and RNFL thickness (superior, rho = -0.358, p = 0.04; inferior, rho = -0.345, p = 0.04; nasal, rho = -0.417, p = 0.01; temporal, rho = -0.390, p = 0.02). The highest level of correspondence between disc pallor and RNFL thickness values outside of the normative 95th percentiles was 39.3% and occurred in the inferior quadrant. CONCLUSIONS: Optic disc pallor in TON was quantified with ImageJ and was significantly correlated with RNFL thickness abnormalities. Thus, ImageJ evaluations of disc pallor may be useful for evaluating RNFL thinning, as verified by OCT RNFL analyses.
Adolescent
;
Adult
;
Child
;
Child, Preschool
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Colorimetry/methods/standards
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Diagnosis, Computer-Assisted/*methods/standards
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Female
;
Humans
;
Male
;
Middle Aged
;
Optic Atrophy/etiology/*pathology
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Optic Nerve Diseases/etiology/*pathology
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Optic Nerve Injuries/*pathology
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Photography/*methods/standards
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Reproducibility of Results
;
Software
;
Tomography, Optical Coherence/*methods/standards
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Trauma Severity Indices
;
Young Adult
5.Clinical Usefulness of Cervicogram as a Primary Screening Test for Cervical Neoplasia.
Young Tae KIM ; Jae Wook KIM ; Sung Hoon KIM ; Yu Ri KIM ; Jae Hoon KIM ; Bo Sung YOON ; Yong Won PARK
Yonsei Medical Journal 2005;46(2):213-220
The purpose of this study is to evaluate the clinical usefulness of the cervicogram as a primary screening test for cervical neoplasia. A total of 294 women who had undergone a cervicogram and a Pap test between January and July 2003, were selected. The diagnostic accuracy of the Pap test, cervicogram, and the Pap test combined with a cervicogram were compared with the histopathologic diagnosis. Among 294 women, the Pap test was negative in 130 cases and positive in 164 cases. Among patients with positive Pap test, cervicogram were negative in 101 cases (61.6%) and positive in 63 cases (38.4%). The diagnostic accuracy between cervicogram with positive Pap test and histology was as follows; sensitivity 44.9%, specificity 78.3%, positive predictive value 84.1%, negative predictive value 32.7%, false positive rate 15.9%, and false negative rate 67.3%. Although the adjunctive use of cervicogram with the Pap test in the initial screening of cervical neoplasia showed a higher specificity and higher positive predictive value compared to the Pap test alone, consideration in terms of lower sensitivity, lower positive predictive value, higher false positive rate and cost-effectiveness should be given in lieu of clinically applying cervicogram with the pap test as an initial screening test.
Adult
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Aged
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Aged, 80 and over
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Cervix Neoplasms/diagnosis/*pathology
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Cervix Uteri/*pathology
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Female
;
Humans
;
Mass Screening/*methods
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Middle Aged
;
Photography/*standards
;
Predictive Value of Tests
;
Research Support, Non-U.S. Gov't
;
Sensitivity and Specificity
;
Vaginal Smears
6.Comparison of the Progression of High- and Low-tension Glaucoma as Determined by Two Different Criteria.
Ji Yun LEE ; Kyung Rim SUNG ; Jin Young LEE
Korean Journal of Ophthalmology 2016;30(1):40-47
PURPOSE: To investigate and compare the progression of medically treated primary open angle glaucoma according to the baseline intraocular pressure (IOP). METHODS: This study included a total of 345 eyes from 345 patients (mean follow-up period, 4.5 years). Eyes were classified into either conventional normal tension glaucoma (cNTG, < or =21 mmHg) or conventional high-tension glaucoma (cHTG, >21 mmHg) groups according to the conventional cut-off value of the IOP. Additionally, the median IOP (15 mmHg) was used to create two other groups (median NTG [mNTG] < or =15 mmHg and median HTG [mHTG] >15 mmHg). Using these values, 306, 39, 153, and 192 eyes were assigned to the cNTG, cHTG, mNTG, and mHTG groups, respectively. Glaucoma progression was determined either by optic disc/retinal nerve fiber layer photographs or serial visual field data. RESULTS: Mean reduction of IOP after medical treatment and of central corneal thickness was lower in the cNTG group, while the prevalence of disc hemorrhage and baseline visual field mean deviation did not differ between the cNTG and cHTG groups. A mean reduction in the IOP was observed after medical treatment, and central corneal thickness was lower in the mNTG group; disc hemorrhage was more frequent in the mNTG than in the mHTG group. Among the 345 analyzed eyes, 100 (29%) showed progression during the follow-up period. In the cHTG group, a higher baseline IOP (hazard ratio, 1.147; p = 0.024) was associated with glaucoma progression. Disc hemorrhage (hazard ratio, 15.533; p < 0.001) was also strongly associated with progression in the mNTG group. CONCLUSIONS: Baseline IOP was a significant risk factor for glaucoma progression in cHTG patients (10% of our total participants), while disc hemorrhage showed the strongest association with progression in the mNTG group, indicating that a cut-off value other than the conventional 21 mmHg is required to define true low-tension glaucoma in populations where NTG predominates among all glaucoma patients.
Aged
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Disease Progression
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Female
;
Glaucoma, Open-Angle/*diagnosis
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Gonioscopy
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Humans
;
Intraocular Pressure
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Low Tension Glaucoma/*diagnosis
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Male
;
Middle Aged
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Nerve Fibers/pathology
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Optic Disk/pathology
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Optic Nerve Diseases/*diagnosis
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Photography/standards
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Retinal Ganglion Cells/pathology
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Retrospective Studies
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Tomography, Optical Coherence
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Tonometry, Ocular
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Vision Disorders/diagnosis
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Visual Field Tests/standards
;
Visual Fields