Photoplethysmography(PPG) employs an infrared light-emitting diode to transmit light into the skin noninvasively. Light reflected from blood cells is received by a photocell or phototrotransistor which permits recording of the pulsatile cutaneous microcirculation. The use of PPG for vascular measurements in extremities is not new. Since Hertzmann, in 1938, first described the technique to measure skin blood flow, a few investigators have used PPG for clinical application. However, experimental reports on the photoplethysmographic assessment of blood flow after arterial reanastomosis are rare. We assessed the changes of blood flow after reanastomosis of the femoral artery in rabbits using photoplethysmography. We divided 20 rabbits into 3 experimental groups. In Group I, the femoral artery was surgically exposed and clamped for 60 minutes. In Group II, the femoral artery was surgically exposed and clamped, as in Group I, and then severed and anastomosed crudely in order to creat thrombus formation. In Group IU, the femoral artery was prepared as Group II and then anastomosed carefully to ensure patency. Blood flow was measured by photoplethysmography on the anteromedial aspect of the right hind leg, every 15 minutes for the fisrt 2 hours, at the 3rd day, I week, and II weeks post-operatively. The following results were obtained l. After the removal of vascular clamp, the mean time for the pulse wave to return to normal form was 63±24.0 minutes in Group I and 63±18.7 minutes in Group III. There was no statistically significant difference beween the two groups. When the wave form was normalized, it remained so continuously. 2. After the removal of vascular clamp, the mean time for the wave amplitude to return to normal was 108±11.2 minutes in Group I and 102±16.4 minutes in Group III. There was no statistically significant difference between the two groups. 3. The thrombosis which obstructed blood flow was formed within the first 60 minutes(mean time: 49±12.4 minutes) in all the animals in Group II. When the thrombosis was formed, it was readily detected by the change of wave form and by decrease in amplitude. 4. It is concluded from this experiments the changes of blood flow after reanastomosis of the femoral artery in rabbits were accurately assessed by PPG. It is suggested that PPG can be used clinically in monitoring blood flow after arterial reanastomosis.
Animals ; Blood Cells ; Extremities ; Femoral Artery ; Humans ; Leg ; Microcirculation ; Photoplethysmography ; Rabbits ; Research Personnel ; Skin ; Thrombosis

No abstract available.
Rabbits*

No abstract available.
Diagnosis* ; DNA* ; Ichthyosis* ; Xeroderma Pigmentosum*

The purpose of study was to examine the effect of supportive touch on the surgical patients with anxiety in the operation room. The method of this study has been carried out under the similar experiment of Nonequivalent control group pretest-posttest design by conveniently selecting 25 experimental group and 25 control group totalling 50 patients in immediatery prior to surgery in the operation room. The data were collected from June. 22, 1998 through Aug. 28, 1998 at C-University hospital in Seoul. The subjects were 50 adult patients who were operated under general anesthesia and had undergone laparotomy. They did not have any complication, were alert enough to be interviewed and agreed willingly to participate in this study. The tool for measurement was the testing protocol for Trait-State anxiety developed by spilberger and the visual analogue scale developed by cline etc. and blood pressure, pulse rate and respiration rate and blood sugar level. SPSS program was used for the analysis. The hemogenety of the control and experimertal group was examined by x2-test and t-test. The results of this study are as follows: 1. There was the significant difference of the state anxiety between the experimental group and the control group (P=0.012) Just before surgery. 2. There was a partially significant difference in the vital signs between the experimental group and control group just before surgery. (systolic blood pressure: P=0.000, diastolic blood pressure: P=0.972, pulse rate: P=0.572, resp rate: P=0.186). 3. There was the significant difference of the blood sugar level between the experimental group and the control group(P=0.002) just before surgery. 4. There was a partially significant difference in the vital signs and blood sugar level of the experimental group and the control group when pre-therapeutic and post-therapeutic readings were compared. (systolic blood pressure: P=0.000, diastolic blood pressure: P=0.035, pulse rate: P=0.796, resp rate: P=0.242, blood sugar level: P=0.002).
Adult ; Anesthesia, General ; Anxiety* ; Blood Glucose ; Blood Pressure ; Heart Rate ; Humans ; Laparotomy ; Reading ; Respiratory Rate ; Seoul ; Vital Signs

During the period from January 1987 to May 1988, arthroscopic partial meniscectomy had been performed in 95 knees of 94 patients. Of the 94 patients, there were 66 males and 28 females ranging in age from 10 to 49 years(mean, 27.4 years). The mean follow up period was 22.1 months (range, 15 to 32 months). Both medial and lateral menisci were affected in 6 knees, so 101 menisci were removed. In the group studied, there were 35 tears of medial, 29 tears of lateral and 37 tears of discoid meniscus. In the 101 tears of meniscus, 22 cases of longitudinal tear, 37 cases of bucket handle tear, 19 cases of flap tear, 13 cases of transverse tear, 5 cases of horizontal tear and 5 cases of complex tear were observed. Most frequently associated lesion was ACL injury (9 cases), and 4 cases of loose body and 4 cases of synovial plica syndrome were also found. The sensitivity of diagnosis with physical examination only was 63.6% and improved with arthrography to 70.4%, and with arthrography and CT to 80.0%. Satisfactory result including excellent and good was 76.6% and no major complication was accompanied.
Arthrography ; Diagnosis ; Female ; Follow-Up Studies ; Humans ; Knee ; Male ; Menisci, Tibial ; Physical Examination ; Tears

From March 1988 to August 1989, 51 knees with clinically suspected meniscus injuries were examined by both MRI and arthroscopy and compared their findings prospectively on the basis of arthroscopic findings to determine the accuracy of MRI in detecting meniscus injury of the knee. We used 2.0 tesla superconducting magnet imager(Spectro-20000, GoldStar, Korea) to obtain MR imaging. Our protocol for imaging was producing Tl sagittal images by spinecho technique and T2 coronal images by gradient echo technique, interleaved at 4mm continuously while the patient's knee was in 8–10 degrees of external rotation and surface coil was placed posteriorly to the knee in supine position. We grouped and correlated the findings of MRI with the arthroscopic findings. With this noninvasive MRI, we could obtain multiplanar, high quality images without compliations. Compared with the arthroscopic findings, MRI resulted in a high diagnostic accuracy of 96 and 86 percent for the medial and lateral meniscus, respectively. And it aided in optimal surgical planning for the clinically suspected meniscus injuries.
Arthroscopy ; Knee ; Magnetic Resonance Imaging ; Menisci, Tibial ; Prospective Studies ; Supine Position

A subperiosteal ganglion has been very rarely reported, since Ollier reported first one in 1864. A subperiosteal ganglion is produced by mucoid degeneration and cyst formation within the periosteum, which results in cortical erosion. The characteristic plain radiolographic appearance of irregular cortical erosion and scalloping, with reactive periosteal bone spicules, has been considered pathognomonic of subperiosteal ganglion. Magnetic resonance imaging is performed to further characterize the soft tissue component of the mass. As in our patient, the characteristic signal intensities of magnetic resonance imaging are especially useful in identifying the lesion as a ganglion and in defining the lobular nature and the anatomical extent. We report here the case of a 35-year-old female who had a sudperiosteal ganglion of the distal radius.
Adult ; Female ; Ganglion Cysts* ; Humans ; Magnetic Resonance Imaging ; Pectinidae ; Periosteum ; Radius*

In nonsystemic vasculitic neuropathy, clinically only nerves are affected : there are no or few constitutional symptoms or serological abnormalities. The clinical and pathological features are those of an ischemic neuropathy caused by a necrotizing vasculitis of small arterioles. This is a case report of nonsystemic vasculitic neuropathy in a 22-year-old male who has the distal symmetric poIyneuropathy as a symptom of localized vsaculitis. The sural nerve biopsy showed a few myelin digestion chamber suggesting axonal degeneration. The patient was treated with steroid daily with gradual clinical and electorophysiological improvement.
Arterioles ; Axons ; Biopsy ; Digestion ; Humans ; Male ; Myelin Sheath ; Sural Nerve ; Vasculitis ; Young Adult

The kidney and balances of fluid and volume are the basic components of bloocl pressure control, and the kidney is the primary site that initiates the hypertensive process and is affected by hypertensive vascular disease. In the kidney, the dopamine is a potent natriuretic and vasodilating agent, participat- ing in renal sodium excretion and maintenance of cardiovascular homeostasis. And the dopamine receptors in central nervous system and peripheral organs were identified by physiological, biochernical and radioligand binding techniques. Rut previous morphological and biochemical studies have been unable to characterize or determine the tissue distribution of the dopamine receptor subtypes because no selective ligands are available yet. Furthermore, the cellular distribution of the dopamine receptor subtypes in the rat kidney is not demonstrated well. In the SHR, the ability of exogenous and endogenous renal dopamine to engender a natriuresis is impaired. Since renal dopamine levels in genetic models of hypertension are not lower than their normotensive controls, the impaired intrarenal paracrine effect of dopamine in these animal models of hypertension appears to be receptor or postreceptor mediated. And renal dopamine derives mainly from renal tubular dopamine production and to a lesser extent from dopaminergic nerves. The present study utilizes imrnunohistochemistry with specific antibodies to characterize the renal distribution of dopamine receptor subtypes and recognize the role of dopamine receptor defect in the pathogenesis of hypertension in 14-week-old WKY (mean HP 108+/-5mmHg) and SHR (mean RP 174+/-7 mmHg) kidneys. Also it utilizes antibody of tyrosine hyclroxylase (TH) to recognize the site of the dopamine production mediated by TH using light microscopic immunohistochemistry. In the immunohistochemistry of the WKY kidney, dopamine D1 receptor protein is localized to glomerulus, proximal tubule, distal tubule, renal vessels, cortical and medullary collecting duct. And in the SHR kidney, dopamine D1 receptor protein is localized to glomerulus, distal tubule, renal vessels, cortical and medullary collecting duct, and juxtaglomerular apparatus (JGA). But there is no demonstrable positive reaction in the proximal tubule and weakly positive reactions in the renal arterioles of SHR compared with WKY kidney. In the immunohisto-chemistry of the WKY kidney, dopamine D1 receptor protein is localized to glomerulus, proxirnal tubule, distal tubule, renal vessels, cortical and rnedullary collecting duct. And in the SHR kidney, dopamine D2 receptor protein is localized to glomerulus, distal tubule, renal vessels, cortical and medullary collecting duct, and JGA. So, there is no demonstrable positive reaction in the proximal tubule of SHR compared with WKY. In the glomerulus of the WKY and SHR kidneys, both dopamine D1 and D2 receptors are localized. In the in situ hybridization of the WKY and SHR kidneys, dopamine D and D receptors are only demonstrated at the renal vessels. The positive reaction to TH immunohistochemistry of the WKY and SHR kidneys is only observed in the renal medulla compared with negative reaction on the renal cortex. Considering the excretion of sodium up to 65-70% with volume expansion may be mediated by dopamine D1-like receptors in the proximal tubule, our immunohistochemistry findings for the dopamine receptors may support the failure of natriuretic response in the SHR due to an abnormal dopamine receptor. Also our results rnay mean that the glornerular filtration rate is mediated by both dopamine D1 and Dz receptors comparing with the previous studies that the glomerular filtration rate was mediated by dopamine D2 receptor. I'here are some differences in the receptors expressing sites on the previous radioligand binding and pharmacologic studies, but our results suggest that at least some of the renal dopamine DA and DAz receptors correspond structurally to the central dopamine D1 and D2 receptors. Finally the result of TH immunohisto-chemistry suggests that the production of dopamine in the proximal tubule is not mediated by TH.
Animals ; Antibodies ; Arterioles ; Central Nervous System ; Dopamine* ; Filtration ; Glomerular Filtration Rate ; Homeostasis ; Hypertension ; Immunohistochemistry* ; In Situ Hybridization ; Juxtaglomerular Apparatus ; Kidney* ; Ligands ; Models, Animal ; Models, Genetic ; Natriuresis ; Rats* ; Rats, Inbred SHR* ; Receptors, Dopamine ; Receptors, Dopamine D1 ; Receptors, Dopamine D2 ; Sodium ; Tissue Distribution ; Tyrosine ; Vascular Diseases

Rhus has been known to one of the most frequent plants which produce allergic contact dermatitis. Allergenic component of thus is urushiol which is composed of catechols with a 15-carbon-atom side-chain. Systemic administration can produced hematogenous contact dermatitis and also severe systemic reactions such as drowsiness, convulsion, nausea, vomiting, glomerulonephritis and urticaria. We experienced a case of right anterior and posterior watershed cerebral infarction, generalized urticaria and allergic contact dermatitis following ingestion of urushiol.
Catechols ; Cerebral Infarction* ; Dermatitis, Allergic Contact ; Dermatitis, Contact ; Eating* ; Glomerulonephritis ; Nausea ; Rhus ; Seizures ; Sleep Stages ; Urticaria ; Vomiting