1.Asymptomatic Pheochromocytoma: A case report.
Myung Soo MA ; Kweon Cheon KIM ; Young Don MIN ; Seong Hwan KIM ; Hyun Jin CHO ; Tae Hyung CHO
Journal of the Korean Surgical Society 1998;54(4):607-612
Pheochromocytomas are catecholamine-producing tumors that typically cause hypertension. They are rare tumors that can pose problems in diagnosis and detection. Although they usually present classic symptoms, they can at times present symptoms that mimic other clinical conditions. Especially, children have fewer malignant tumors, non-extra-adrenal tumors, and tumors with greater bilaterality and multiplicity. The diagnosis of pheochromocytomas is based upon clinical suspicion and biochemical study. Radiologic localization is obtained before operation because of the variable location of this tumor. The treatment of choice is surgical resection. We reports a case of asymptomatic pheochromocytoma that was treated with tumor excision. To prevent intraoperative and postoperative complications, precise preoperative diagnosis and localization, as well as adequate preoperative management, are necessary.
Child
;
Diagnosis
;
Humans
;
Hypertension
;
Pheochromocytoma*
;
Postoperative Complications
2.Phaeochromocytoma presenting with pseudo-intestinal obstruction and lactic acidosis.
Peng Chin KEK ; Emily Tse Lin HO ; Lih Ming LOH
Singapore medical journal 2015;56(8):e131-3
Phaeochromocytomas are rare neuroendocrine tumours with variable clinical signs and symptoms. Hypertension, tachycardia, sweating and headaches are cardinal manifestations. Although nausea and abdominal pain are the more common gastrointestinal features, rare gastrointestinal spectrums have been reported that can mimic abdominal emergencies. Metabolic effects of hypercatecholaminaemia are vast and one such rare presentation is lactic acidosis. We describe a case of phaeochromocytoma presenting with both intestinal pseudo-obstruction as well as lactic acidosis. This case report highlights the importance of having a high index of suspicion for and early recognition of the gastrointestinal and metabolic manifestations of phaeochromocytomas.
Abdominal Pain
;
Acidosis, Lactic
;
complications
;
Adrenal Gland Neoplasms
;
complications
;
diagnosis
;
Diabetes Mellitus, Type 2
;
complications
;
Dyslipidemias
;
complications
;
Female
;
Humans
;
Hypertension
;
complications
;
Intestinal Pseudo-Obstruction
;
complications
;
Middle Aged
;
Neuroendocrine Tumors
;
complications
;
diagnosis
;
Pheochromocytoma
;
complications
;
diagnosis
;
Radiography, Abdominal
3.Severe Posterior Reversible Encephalopathy in Pheochromocytoma: Importance of Susceptibility-Weighted MRI.
Asli SERTER ; Alpay ALKAN ; Ayse ARALASMAK ; Ercan KOCAKOC
Korean Journal of Radiology 2013;14(5):849-853
Pheochromocytoma is a rare cause of hypertension in children. Hypertension is one of the common reasons of posterior reversible encephalopathy. Intracerebral hemorrhage is a serious and unexpected complication of hypertensive encephalopathy due to pheochromocytoma, and very rarely seen in the childhood. Intracerebral hemorrhages should be searched if there are hypertensive reversible signal changes on the brain. Susceptibility weighted imaging (SWI) is a more sensitive method than conventional MRI when demonstrating cerebral microhemorrhagic foci. This is the first report of SWI findings on intracerebral hemorrhages in basal ganglia, brain stem and periventricular white matter due to hypertensive encephalopathy in a child with pheochromocytoma.
Adolescent
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Adrenal Gland Neoplasms/*complications/diagnosis
;
Brain/*pathology
;
Diagnosis, Differential
;
Female
;
Humans
;
Hypertensive Encephalopathy/*diagnosis/etiology
;
Magnetic Resonance Imaging/*methods
;
Pheochromocytoma/*complications/diagnosis
4.Pheochromocytoma complicated with cardiomyopathy after delivery--a case report and literature review.
Hyun Joong KIM ; Duk Kyung KIM ; Sang Chul LEE ; Soon Ha YANG ; Jung Hyun YANG ; Won Ro LEE
The Korean Journal of Internal Medicine 1998;13(2):117-122
Pheochromocytoma in pregnancy is very rare but it is associated with very high maternal and fetal mortality. Therefore, it is important to include pheochromocytoma in the differential diagnosis of hypertension associated with pregnancy. It is difficult to make a diagnosis of pheochromocytoma in pregnancy before delivery. The characteristic symptoms of pheochromocytoma could be initiated during delivery because the process of delivery, general anesthesia, fetal movement, induce acute surge of catecholamine release, which could also induce cardiomyopathy. Early diagnosis and intensive care can affect the prognosis of cardiomyopathy induced by pheochromocytoma. Proper management with alpha-blockade, beta-blockade and angiotension converting enzyme inhibitor could acutely reverse the course of cardiomyopathy.
Adrenal Gland Neoplasms/surgery
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Adrenal Gland Neoplasms/diagnosis*
;
Adrenal Gland Neoplasms/complications
;
Adult
;
Cardiovascular Agents/therapeutic use
;
Disease-Free Survival
;
Echocardiography
;
Electrocardiography
;
Female
;
Human
;
Myocardial Diseases/ultrasonography
;
Myocardial Diseases/etiology*
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Myocardial Diseases/drug therapy
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Pheochromocytoma/surgery
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Pheochromocytoma/diagnosis*
;
Pheochromocytoma/complications
;
Pregnancy
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Pregnancy Complications, Cardiovascular/etiology*
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Pregnancy Complications, Neoplastic/surgery
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Pregnancy Complications, Neoplastic/diagnosis*
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Pregnancy Outcome*
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Puerperium
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Tomography, X-Ray Computed
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Substances: Cardiovascular Agents
5.Adrenal tumours in pregnancy: diagnostic challenge and management dilemma.
Jessie Wai Leng PHOON ; Devendra KANALINGAM ; Hong Liang CHUA
Singapore medical journal 2013;54(7):e141-5
Adrenal gland tumours in pregnancy are very rare occurrences and have highly variable clinical presentations. The timely diagnosis of adrenal tumours in pregnancy is extremely important, as failure to do so may lead to fatality. As there is limited published literature on adrenal tumours in pregnancy and no consensus on its management, the management of such patients with regard to medical and surgical treatments, as well as timing of delivery, must therefore be individualised and carried out with multidisciplinary expertise. We present two cases of adrenal tumours in pregnancy, both with favourable outcomes and variable gestations. Our first and second cases discuss a large phaeochromocytoma and a cortisol-secreting adrenal cortical adenoma in pregnancy, respectively.
Adrenal Gland Neoplasms
;
diagnosis
;
surgery
;
Adrenalectomy
;
Adult
;
Biomarkers
;
blood
;
urine
;
Diagnosis, Differential
;
Female
;
Humans
;
Laparoscopy
;
Magnetic Resonance Imaging
;
Pheochromocytoma
;
diagnosis
;
surgery
;
Pregnancy
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Pregnancy Complications, Neoplastic
;
diagnosis
6.Transperitoneal Laparoscopic Adrenalectomy: A Single Surgeon Experience.
Min Young PARK ; Byong Chang JEONG ; Hyeon Hoe KIM
Korean Journal of Urology 2005;46(11):1119-1124
PURPOSE: We present a single surgeon experience of 52 cases of transperitoneal laparoscopic adrenalectomy for various adrenal diseases. MATERIALS AND METHODS: Transperitoneal laparoscopic adrenalectomy (n= 52) for various adrenal diseases was performed by a single surgeon from February 1998 to December 2004. Clinical diagnosis of the subjects included 17 cases of primary aldosteronism, 11 of adrenal adenoma causing Cushing's syndrome, 3 of pheochromocytoma and 21 of nonfunctioning adenoma. The 52 patients were divided into 3 groups according to the time when operations were performed: early group of 18 patients, intermediate group of 17 patients, and late group of 17 patients. The mean operative time, mean estimated blood loss (EBL) and complication of each group were investigated to analyze the single surgeon's learning curve. RESULTS: All laparoscopic adrenalectomies were successfully completed in all 52 patients. The mean operative time, mean EBL, mean tumor size, and mean postoperative hospital stay were 124 minutes (60-360), 56cc (30-300), 2.7cm (1-4.7), and 3.8 days (3-8), respectively. The mean time to solid diet and ambulation were 1.5 days and 1 day, respectively. There was no serious intraoperative or postoperative complication. Statistically, the mean operative time and estimated blood loss showed a significant reduction in the intermediate and late group compared with the early group. CONCLUSIONS: Our results showed that transperitoneal laparoscopic adrenalectomy is a safe and effective surgical treatment modality in adrenal diseases.
Adenoma
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Adrenal Gland Diseases
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Adrenalectomy*
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Cushing Syndrome
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Diagnosis
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Diet
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Humans
;
Hyperaldosteronism
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Laparoscopy
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Learning Curve
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Length of Stay
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Operative Time
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Pheochromocytoma
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Postoperative Complications
;
Walking
7.A case of pheochromocytoma manifested diabetic ketoacidosis.
Jung Hwa RYU ; Chang Yoon HA ; Jee Young OH ; Young Sun HONG ; Yeon Ah SUNG
Korean Journal of Medicine 2003;65(Suppl 3):S844-S848
A 45-year-old woman was admitted with the diagnosis of diabetic ketoacidosis (DKA). During the hospital course, fluctuation of blood pressure accompanying with headache and palpitation was noted. The diagnosis of pheochromocytoma was proven by elevated urinary catecholamine and its metabolite, and confirmed histologically after right adrenalectomy. Mild glucose intolerance is known to be associated with pheochromocytoma in many cases. However, acute diabetic complication such as DKA has been reported in only 4 cases, mainly in Japanese. We think this is the first case of pheochromocytoma manifested DKA in Korea, so we report this with literature review.
Adrenalectomy
;
Asian Continental Ancestry Group
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Blood Pressure
;
Diabetes Complications
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Diabetic Ketoacidosis*
;
Diagnosis
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Female
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Glucose Intolerance
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Headache
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Humans
;
Korea
;
Middle Aged
;
Pheochromocytoma*
8.A functioning adrenal adenoma and pheochromocytoma in the same adrenal gland: two discrete adrenal incidentalomas.
Ga Eun PARK ; Yoon Young CHO ; Yun Soo HONG ; Su Hoon KANG ; Kyung Ho LEE ; Hyun Woo LEE ; Jae Hyeon KIM
The Korean Journal of Internal Medicine 2015;30(1):114-117
No abstract available.
Adrenal Cortex Function Tests
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*Adrenal Cortex Neoplasms/complications/diagnosis/metabolism/surgery
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*Adrenal Gland Neoplasms/complications/diagnosis/metabolism/surgery
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Adrenalectomy
;
*Adrenocortical Adenoma/complications/diagnosis/metabolism/surgery
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Biopsy
;
Cushing Syndrome/diagnosis/etiology
;
Female
;
Humans
;
Immunohistochemistry
;
*Incidental Findings
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Middle Aged
;
*Neoplasms, Multiple Primary/complications/diagnosis/metabolism/surgery
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*Pheochromocytoma/complications/diagnosis/metabolism/surgery
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Predictive Value of Tests
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Tomography, X-Ray Computed
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Treatment Outcome
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Tumor Markers, Biological/metabolism