No abstract available.
Phenobarbital*

Objective To investigate the current status of treatment for patients with convulsive epilepsy in rural areas of Heilongjiang Province， China and the efficacy of phenobarbital in the treatment of epilepsy， and to evaluate the effect of the epilepsy prevention and management project in rural areas. Methods EpiData， EXCEL， and SPSS 19.0 were used for data entry， processing， and statistical description to analyze the current status of epilepsy treatment in rural areas， the dose of phenobarbital， and the frequency of seizures. In the epilepsy prevention and management project of Heilongjiang Province in 2015—2020， a total of 908 patients with convulsive epilepsy were enrolled in the phenobarbital treatment group， and after standardized treatment and follow-up management， 698 patients were followed up for at least 12 months. Results The gap rate of rural epilepsy treatment in Heilongjiang Province was 56.39%. After one year of standardized treatment， the frequency of seizures decreased from 23.86 times/year before enrollment to 3.11 times/year， showing a significant reduction. The response rate of epilepsy treatment was 68.19%， and the patients without previous standard treatment tended to have a better outcome than those who received standard treatment. Conclusion The current status of epilepsy treatment is not optimistic in rural areas of Heilongjiang Province， and there remains a large gap in epilepsy treatment. It is necessary to strengthen the training on the diagnosis and treatment of epilepsy among primary care physicians and implement the public education on the prevention and treatment of epilepsy， and since phenobarbital has a marked clinical effect in the treatment of epilepsy， it holds promise for further application in rural areas.
Phenobarbital

No abstract available.
Hypersensitivity* ; Phenobarbital*

55 gardenal-poisoned patients were measured the drug’s blood levels to compare with their clinical manifestations and select appropriate treatment methods. The mean value was 36.87mg/l. The patients with the blood gardenal levels equal to or less than 60mg/l usually had first or second-stage coma, mild respiratory failure (if any), and fewer severe complications. This group of patients only required simple measures such as gastric lavage, the use of activated charcoal, enhanced diuresis and urine alkalization. Whereas the patients with the levels more than 60mg/l commonly suffered from third or fourth-degree coma, severe to life-threatening respiratory failure, hypotension and other severe complications. They not only needed simple curative methods but also mechanical ventilation and hemodialysis. the hemodialysis could reduce the blood gardenal concentration up to 665 for each intervention period. Owing to this extracorporeal technique for the removal of toxins, the duration of mechanical ventilation, enhanced diuresis, urine alkalization as well as the necessary amount of bicarbonate was decreased remarkably.
Phenobarbital ; Phenobarbital/poisoning ; Blood ; Diagnosis ; Therapeutics

No abstract available.
Breast Neoplasms* ; Breast* ; Phenobarbital*

No abstract available.
Asphyxia* ; Phenobarbital* ; Seizures*

Humans ; Scopolamine ; Phenobarbital ; Suicide

No abstract available.
Humans ; Male* ; Phenobarbital* ; Young Adult*

No abstract available.
Humans ; Male* ; Phenobarbital* ; Young Adult*

The patent urachus results from failure of luminal closure of the urachus. Embryologically, the urachus represents the vestigial remnant of the allantois which, in the fetus, communicates with the cloaca. The authors report a case of congenital patent urachus with review of some literatures.
Allantois ; Cloaca ; Fetus ; Phenobarbital ; Urachus*