OBJECTIVES: Fibromyalgia is a common rheumatologic disease characterized by chronic myalgia, fatigue, and sleep disturbance. Chronic fatigue syndrome is chracterized by debilitating fatigue of at least 6 months duration accompanied by other symptoms such as fever, pharyngitis, painful lymph nodes, headache, myalgia, sleep disturbances, neurocognitive complaints, and depression. There has reported that 70% of patients with fibromyalgia met the centers for Disease Control and Prevention symptom criteria for chronic fatigue syndrome. The objectives of this study were to determine how frequently patients with fibromyalgia met the criteria for and chronic fatigue syndrome and what symptoms were manifested. METHODS: 34 patients diagnosed with fibromyalgia were participated in the study. The questionnaire made according to the Centers for Disease Control and Prevention criteria was administerd and patients with chronic fatigue syndrome were diagnosed by this questionnaire, physical examination and laboratory tests. RESULTS: 21% (7 patients) of patients with fibromyalgia met the criteria for chronic fatigue syndrome. The symptoms in patients with chronic fatigue syndrome were memory loss/forgetfullness (100%), sore throat (57%), painful lymph node (29%), myalgia (100%), multiple arthralgia (57%), headache (57%), unrefreshing sleep (86%), postexertional malaise (86%). CONCLUSION: 21% of patients diagnosed with fibromyalgia met the criteria for chronic fatigue syndrome. The incidence of chronic fatigue syndrome in our study is low as compared with the previous study (70%) in 1996.
Arthralgia ; Centers for Disease Control and Prevention (U.S.) ; Depression ; Fatigue ; Fatigue Syndrome, Chronic* ; Fever ; Fibromyalgia* ; Headache ; Humans ; Incidence* ; Lymph Nodes ; Memory ; Myalgia ; Pharyngitis ; Physical Examination ; Surveys and Questionnaires

Since the World Health Organization has officially declared a global influenza pandemic, the number of human cases of pandemic influenza A (H1N1) in 2009 has been increasing in many countries. Especially from mid-October, the number of domestic cases of influenza A (H1N1) has been exponentially increasing, with the number of confirmed cases reaching over 100,000. The clinical symptoms of novel influenza A (H1N1) include fever, cough, sore throat, runny nose, myalgia, headache, chills and fatigue. Nucleic acid amplification tests, including real time RT-PCR assay specific for 2009 novel influenza A (H1N1) can be used in the patients with suspected influenza. Antiviral treatment by using neuraminidase inhibitors (oseltamivir, zanamivir) is recommended by Centers for Disease Control and Prevention for treatment of novel influenza A (H1N1) disease. Personal and public efforts to control the outbreak of novel influenza A (H1N1) disease are required. Vaccination against pandemic H1N1 is important for personal health, but also to build community-level immunity to novel influenza A.
Centers for Disease Control and Prevention (U.S.) ; Chills ; Cough ; Fatigue ; Fever ; Headache ; Humans ; Influenza, Human ; Neuraminidase ; Nose ; Nucleic Acid Amplification Techniques ; Oseltamivir ; Pandemics ; Pharyngitis ; Vaccination ; World Health Organization ; Zanamivir

These guidelines were developed as part of the 2016 Policy Research Servicing Project by the Korea Centers for Disease Control and Prevention. A multidisciplinary approach was taken to formulate this guideline to provide practical information about the diagnosis and treatment of adults with acute upper respiratory tract infection, with the ultimate aim to promote the appropriate use of antibiotics. The formulation of this guideline was based on a systematic literature review and analysis of the latest research findings to facilitate evidence-based practice, and focused on key questions to help clinicians obtain solutions to clinical questions that may arise during the care of a patient. These guidelines mainly cover the subjects on the assessment of antibiotic indications and appropriate selection of antibiotics for adult patients with acute pharyngotonsillitis or acute sinusitis.
Adult* ; Anti-Bacterial Agents ; Centers for Disease Control and Prevention (U.S.) ; Diagnosis ; Evidence-Based Practice ; Humans ; Korea ; Pharyngitis ; Respiratory Tract Infections* ; Sinusitis ; Tonsillitis

OBJECTIVE: To explore the effectiveness and feasibility of dexamethasone combined with oxybuprocaine hydrochloride gel on the prevention of postoperative sore throat after nasal endoscopy. METHODS: In the study, 60 patients with American Society of Anesthesiologist (ASA) physical statuses Ⅰ to Ⅱ, aged 18 to 72 years, scheduled for elective nasal endoscope surgery under general anesthesia requiring endotracheal intubation were randomly divided into dexamethasone combined with oxybuprocaine hydrochloride gel group (G group, n=30) and control group (C group, n=30). The patients in the G group received dexamethasone 0.1 mg/kg before induction and the oxybuprocaine gel was applied to the endotracheal catheter cuff and the front end within 15 cm. The patients in the C group received the same dose of saline and the saline was applied to the endotracheal catheter cuff and the front end within 15 cm. Then, all the patients in the two groups received the same induction and anesthesia maintainance. The operation time, anesthesia time, emergence time, extubation time and departure time were recorded. The intraoperative infusion volume, blood loss volume, propofol, remifentanil, rocuronium dosage were also recorded. The adverse reactions such as intraoperative hypotension, bradycardia and postoperative agitation were recorded. The postoperative sore throat score was recorded at the end of operation and 4 h, 8 h, 12 h, and 24 h after operation. RESULTS: Compared with the C group, the emergence time [(8.4±3.9) min vs. (10.8±4.7) min], extubation time [(8.8±3.7) min vs. (11.9±4.8) min], and departure time [(20.0±5.3) min vs. (23.0±5.8) min] were significantly shorter, and the propofol dosage [(11.8±1.8) mg/kg vs. (15.9±4.6) mg/kg], remifentanil dosage [(10.9±4.7) μg/kg vs. (14.1±3.6) μg/kg] were significantly less in the G group, and there was no difference of rocuronium dosage in the two groups. Compared with the C group the incidence of intraoperative hypotension [10%(3/30) vs. 30%(9/30)], bradycardia [16.7%(5/30) vs. 20%(6/30)] and postoperative agitation [6.7%(2/30) vs. 23.3%(7/30)] were significantly lower in the C group. The postoperative sore throat score at the end of operation, 4 h, 8 h, 12 h and 24 h after operation in the G group were significantly lower than in the C group respectively [0 (0, 1) vs. 1 (1, 2), 0 (0, 0) vs. 1 (1, 2), 0 (0, 0) vs. 1 (1, 2), 0 (0, 0) vs. 1 (0.75, 1), 0 (0, 0) vs. 1 (0, 1)]. CONCLUSION Dexamethasone combined with oxybuprocaine hydrochloride gel was effective and feasible on the prevention of postoperative sore throat after nasal endoscopy.
Adolescent ; Adult ; Aged ; Bradycardia/drug therapy* ; Dexamethasone/therapeutic use* ; Endoscopy/adverse effects* ; Humans ; Hypotension/drug therapy* ; Intubation, Intratracheal/adverse effects* ; Middle Aged ; Pain/drug therapy* ; Pharyngitis/prevention & control* ; Postoperative Complications/prevention & control* ; Procaine/analogs & derivatives* ; Propofol ; Remifentanil ; Rocuronium ; Young Adult

OBJECTIVES:It was reported that fatigue was the seventh most common symptom in primary care and 24% of the general adult population had fatigue lasting 2 weeks or longer in the united states. No medical cause was found in 59% to 64% of those persons. Chronic fatigue syndrome is chracterized by debilitating fatigue of at least 6 months duration accompanied by other symptoms such as fever, pharyngitis, painful lymph nodes, headache, myalgia, sleep disturbances, neurocognitive complaints, and depression. Idiopathic chronic fatigue is defined as clinically evaluated, unexplained chronic fatigue that fails to meet criteria for the chronic fatigue syndrome. The objectives of this study were to determine the prevalence of idiopathic chronic fatigue and chronic fatigue syndrome (CFS) in Korea and to analysis the symptoms of those patients. METHODS: Five hundred thirty persons who visited Korea university hospital health management center between March 1998 and June 1998 were participated in the study. The questionnaire made according to the Centers for Disease Control and Prevention criteria was administerd and patients with idiopathic chronic fatigue and chronic fatigue syndrome were diagnosed by this questionnaire, physical examination and laboratory tests. RESULTS: Ten persons(1.9%) met the criteria for chronic fatigue syndrome. and 115 persons (21.7%) met the criteria for idiopathic chronic fatigue. The symptoms in patients with chronic fatigue syndrome were memory loss or forgetfullness(90%), sore throat(20%), painful lymph node(30%), myalgia(80%), multiple arthralgia(20%), headache(50%), unrefreshing sleep(100%), postexertional malaise(90%). CONCLUSION: Persons who met the criteria for chronic fatigue syndrome were found in 1.9%. The incidence of chronic fatigue syndrome in our study was high, compared with previous studies.
Adult ; Centers for Disease Control and Prevention (U.S.) ; Depression ; Fatigue Syndrome, Chronic ; Fatigue* ; Fever ; Headache ; Humans ; Incidence* ; Korea* ; Lymph Nodes ; Memory Disorders ; Myalgia ; Pharyngitis ; Physical Examination ; Prevalence ; Primary Health Care ; United States ; Surveys and Questionnaires