The influence of some medications including medicaments originated plant on the liver and kidney functions and histologic changes in experiemental animal is carried out. The results shows that the liver and kidney function of rabit are not affected by the doses of 10-20 fold higher than clinical doses. Conclusion: These medications can be tried on the clinical at dose of less than 1.0 g/kg of bodyweight within 2 weeks with interval of 1- 2 weeks.
Toxicity ; Cerebrovascular Disorders

There are some inapropriate problems: 1. The number of mice according to method from 30-100; 2. The weight of mice is 16-22g but most common is 19+/-1g(45 days);3. If oral dosage: 0.2 ml/10 g mice, if body weight:19+/- 1 g: the same dose of 0.4-0.5 ml/mice; 4. As calculating method of Behrens, the number of mice can provide LD 50 with small adds; 5. Safe maximal dose; 6. The mice is monitored mainly during first 24 hours. The monitoring time may be 36-48 hours; 7. The morphological, frequency and amplitude change of all waves in electrocardiogram and encephalogram should be nomitored.
Acute Toxicity Tests

Our experimental results showed that: 1. EBS1 have low acute toxicity in experimental models. 2. When EBS1 were administered to animals per os, the different parameters have no signification for: weight, liver, spleen, kidney, blood and biochemistry in comparision with control ones.
Toxicity

The vertical HIV transmission from mother to infant can occur in the pregnant period (in utero), during labor or after delivery from breastfeeding. It’s difficult to diagnose HIV-infected newborns by means of serology test, since IgG antibody can infiltrate through placenta from HIV-infected mothers and therefore the serology test is always positive in their babies, even in case the babies were not HIV-infected. In this study, the vertical mother-to-infant HIV-1 transmission in utero was detected by using polymerase chain reaction (PCR) with p17, c2v3 (gp120) and gp41 primers. 37 of 37 (100%) mother blood specimens and 2 of 37 (5.4%) their newborn umbilical cord blood samples were HIV-1 PCR positive. The PCR success rate with P17 and gp41 primers was much higher than that of PCR with c2v3 primer, especially on umbilical cord blood samples. It is recommended that a PCR test using the least 2 primers (p17 and gp41) should be performed at birth to detect HIV-1 seropositive infants and to allow the initiation of antiretroviral therapy. It is necessary to follow up baby health and perform repeatedly HIV-1 PCR on their blood samples to diagnose the timing of HIV-1 transmission.
Plants ; Monoamine Oxidase Inhibitors ; Plants, Medicinal

Counting the average number and standard error or standard deviation by popular method of 3 groups also leads to correct results as using Microsoft Excel software. When using Summary Statistics in Descriptive Statistics, we have average value, standard error, standard deviation and other results, in which there was a sample variance. If 2 variances of 2 samples were the similar, t test has been used. Thus, using Microsoft Excel software, we’ll have specific p value. From that, we could infer the greater or smaller results
Statistics Computer

The study was carried out on rabbits at the daily dose of 6 g and 12 g/kg body weight. After 30 days, the activity of the rats in the experimental groups (receiving plant extract) and the control group (receiving distilled water) remained in the normal state. The measurements, such as the amount of red blood cells, platelets, white blood cells, the leucogram, hematochrome, hematocrit, mean corpuscular volume, showed no difference in the two experimental groups of rats (15 and 30 day-regimens) compared with the control group, and with before the administration of the extract. Therefore, the fruit extract of Morinda citrifolia had no effects on the health state and the hematogenic system of the experimental rabbits.
Morinda ; Plants ; Plants, Medicinal ; rats ; Constitution and Bylaws

Two models: experimental traumatic edema (I) and 1% carrageenin-induced edema (II), were developed on rats for the study of the anti-inflammatory effects of drugs, I being superior to II as for the efficacity and appropriate treatment. The model for the study of the analgesic effect was developed by pressing on rat legs. Of the various prescriptions prepared from a traditional massage tincture, the formulations of 5% propylene glycol and emulgel were more effective in anti-inflammation and analgesia than the tincture itself.
Massage ; Anti-Inflammatory Agents ; Analgesics

The water extracts of Macrotermes anadelei and Polyrachis dives were shown to improve the memorization power of rats at the dose of 10 mg/kg body weight. After the 21-days training for one trial learning avoidance test, the time the rats remained in the bright chamber was reduced to 47.2% for those received M. anadelei, and 43.6% for P. dives, not significantly lower than Ginkgo biloba (50.6%). In Morris Water Maze, both those extracts were also proved to boost the process of learning and memorization in mice.
Plants ; Plants, Medicinal ; rats ; Memory ; learning

For treating diabetes, modern medicine used some drugs such as: insulin, sulfonylureas, biguanid, etc. However, long ago people had known to use medicine materials from natural herbs and animals with hypoglycemia and anti-diabetic effects: Pinellia ternata (Thunb.) Breit. Araceae family; Lantana camara L., Verbenaceae family; Platycodon gradiflorum (Jacq.) A. DC., Campanulaceae family; Stevia rebaudiana (Bert) Hemsi, Asteraceae family; Gynostemma pentapbyllum (Thunb.) Mak. Cucurbitaceae family; Calendula officinalis L., Asteraceae family; Morus alba L., Moraceae family; Tinospora cordifolia Miers., Menispermaceae; Rheum, Polygonaceae family; Hordeum vulgare L., Poaceae family; Rehmannia glutinosa (Gaernt.) Libosch., Scrophulariaceae family; Hirudo, Hirudinidae family; Anacardium occidentale L.), Anacardiaceae family; Cordyceps sinensis (Berk.). Succ., Hepialidae family; Prunella vulgaris L.), Lamiaceae family; Allium cepa L., Alliaceae family.ew
Materia Medica ; Hypoglycemia ; Diabetes Mellitus ; Therapeutics

The botanical characteristics of Polygonatum kingianum Coll. et Hemsl. (red Polygonatum) and P. cyrtonema Hua (ginger Polygonatum) were described. The microscopic characteristics were proposed for the standard control of the herbs. The plant rhizomes might be prepared into the form named as cooked Polygonatum
Polygonatum ; Plants ; Plants ; Medicinal