1.Effects of calcium supplemented biscuits on bone density
Journal of Preventive Medicine 2002;12(3):79-85
2 group of 45 women each, 60-70 years of age, were recruited for this study during 6 months. All women did morning physical exercise regularly. The first group received a daily suplementation of 50g biscuits cotaining 400mg calcium gluconate and the second group received the same amount of biscuits without calcium addition. The bone mineral density was measured at baseline and after 6 months. The results: in the calcium group, there was a significant increase of bone mineral density compared to the control group. The mean systolic and mean diastolic blood pressures found decreased in the calcium group and increased in the control group.
bone density
;
Calcium
2.Role of calcium supplemented cakes in the improvement of bone density
Journal of Practical Medicine 2000;391(11):37-38
A public nutritional intervention trial on 45 women (ages of 60-70) by using the calcium complemented cakes and 45 women by using common cakes in Namdong and Giang vo communes, Hanoi capital aimed at evaluating the bone density and cardiovascular indices after intervention. The results have shown that the use of calcium supplemented cakes increased the T score of 0,1g/cm2 in the arm and T score of 0,17g/cm2 in the leg of menopausal women and reduced the systolic and diastolic pressure 2,9mmHg and 3,9 mmHg, respectively.
Bone Density
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Calcium
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Dietary Supplements
3.Concentration of Blood Homocystein in TYP 2 Diabetics
Tuyet Thi Duong ; Huong Thi Nguyen ; Ngoc Thien Pham
Journal of Medical Research 2008;0(1):71-76
Introduction: Diabetes is a serious metabolic disease with chronic and acute complications, especially atherosclerosis. The increase of blood homocystein level is obviously related to blood injuries\u2019 in a number of diseases including diabetes. In Vietnam, blood Homocystein in Diabetics has not been comprehensively studied. \r\n', u'Objectives: The study was conducted with two surveyed groups. Determination of blood homocystein concentration in type 2 diabetics in comparison with a group of normal people. \r\n', u'Subjects and method: The study was conducted on a sample of 57 type 2 diabetics according to WHO-2001 standards and a group of 46 normal people. Concentration of blood homocystein was assayed by a competition fluorescence immunoassay, and by other experiments according to normal biochemical methods.\r\n', u'Results: The tHcy concentration in diabetics is 12.19 \xb1 3.47 mmo/L and in the normal group is 7.87 \xb1 2.26 IJmo/L. \r\n', u'Conclusion: The tHcy concentration in the 57 type 2 diabetics group has a statistically increasing mean in comparison with the normal group for both men and women. However, there is no comparative difference in the tHcy concentration of diabetics in gender and age categories. \r\n', u'
Homocystein
;
Diabetic
4.Morphological structure of dental enamel -cement border of 7th tooth-An electronic scanning microscopy study \r\n', u'\r\n', u'
Thang Xuan Pham ; Vinh Gia Le ; Huong Thi Le
Journal of Medical and Pharmaceutical Information 2003;0(4):34-39
Background: Morphological structure of dental enamel-cement border of the 7th tooth is of great interest to many dentists with various different meanings. Study of the border of the 7th tooth allows the visual description of the morphological structure of this region. Objectives: To highlight the structure of dental enamel-cement border as well as its application in the endodontic treatment. Subjects and methods: The team used screening electronic microscopy to investigate the morphology and structure of twenty, second molar of adults who are between 18 and 35 year old. These teeth were extracted due to dental correction or caries (on chewing face). The study was conducted on both non-demineralized and demineralized teeth. Results: There are 3 kinds of connection in the enamel-cement border area of second molar: cement covering enamel, enamel-mineralized peridental ligament there is a gap between enamel and cement without exposing dentine. The kind of cement covering enamel connection is characteristic for dental interior face. The kind of enamel-mineralized peridental ligament is characteristic for the proximal, distal and middle dental face, the kind of enamel and cement without exposing dentine is characteristic for external face. Conclusion: Research conducted on only a small amount of tooth No. 7, further studies should be carried out on other teeth to have a more accurate description. \r\n', u'\r\n', u'
Morphological structure
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dental
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enamel -cement border of 7th tooth
5.Estimating the effectiveness of nimodipin in treatment of children with intracranial hemorrhage
Huong Thi Thanh Nguyen ; Ung Thi Ninh ; Thong Minh Pham ; Huyen Thi Thanh Ho
Journal of Medical Research 2007;55(6):58-64
Background:Cerebral vasospasm is a proved reaction and nimodipin revolutionised the treatment of subarrachnoid hemorrhage in adult. However, the effectiveness of Nimodipin in cerebral vasospasm remained controversial in intracranial hemorrhage (lCH) in children. Objectives:This study aims to estimate the effectiveness of nimodipin in treatment of children with intracranial hemorrhage.Subjects and method:A descriptive, prospective study was conducted on all children patients diagnosed intracranial hemorrhage and treated at Neurology department of National Hospital for Pediatric, Vietnam from 2004 to June 2007. They applied the Transcranial Doppler sonography (TCD) in diagnosis of vasospasm in intracranial hemorrhage in children and follow-up the evolution after treatment with nimodipin. Results:The results showed that cerebral vasospasm with hight resistance index (RI) on TCD (RI = 0.78 \xb1 0.08) and cerebral ischemie with low systolic velocity (Vs = 68 \xb1 12.2 crn/s) and hight pulsality index (PI = 1.4 \xb1 0.13) were observed in 100% of cases after 3 days with ICH. Nimodipine improved clinical status (71.2%) and CT scan (52%), also RI, PI, Vs returned to normal when used nimodipin within 7 days of ICH. Conclusion: The treatment method for intracranial hemorrhage with nimodipin supplement had proved to have initial effecacy in comparison with traditional method.
Intracranial Hemorrhages/ therapy
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Nimodipine/ therapeutic use
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Infant
6.Studying the therapeutic effects of the traditional remedy of "tu than hoan" in the treatment of irritable bowel syndrome of diarrhea state
Nga Thi Tuyet Nguyen ; Ho Thi Thu Pham ; Huong Tran Giang Nguyen
Journal of Medical Research 2007;47(2):95-100
Background: Irritable bowel syndrome is a diagnosis of exclusion. It is a functional bowel disorder characterized by chronic abdominal pain, discomfort, bloating, and alteration of bowel habits in the absence of any detectable organic cause."Tu than hoan" is a traditional remedy applied for the treatment of syndromes of traditional medicine which have the similar characteristics to irritable bowel syndrome of diarrhea state of modern medicine. Objectives: The study had two purposes: (1)To evaluate the therapeutic effects of the remedy on the clinical symptoms of patients with irritable bowel syndrome of diarrhea state comparing with Duspatalin; (2)To evaluate the side effects of the remedy. Subjects and method:162 patients diagnosed with irritable bowel syndrome of diarrhea state were treated at Bach Mai hospital from March to August 2005. They divided into 2 groups, the control group included 77 patients and the study group included 85 patients. : clinical test, comparing with controls. Results: 80% of patients recovered from diarrhea; 82.4% of patients with defecation returned to normal; 93.6% stopped mucous feces; 76.5% stopped bellyache. Good therapeutic effect was 61.2% (p < 0.05). Conclusions: Tu than hoan had good therapeutic effects in the treatment of irritable bowel syndrome of diarrhea state. None of patients had to discontinue the medicine due to side effects. \r\n', u' \r\n', u'
Irritable Bowel Syndrome/ pathology
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therapy
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Medicine
;
Traditional/ methods
;
utilization
7.Experimental analgesic and acute anti-inflammatory effects of VK2
Que Thi Hoang ; Huong Giang Nguyen Tran ; Anh Thi Van Pham
Journal of Medical Research 2008;55(3):68-73
Background: In traditional medicine, liquid extract VK2 has good effects in the treatment of osteoarticular pain. This remedy has its origin from \u201cTam ty thang\u201d of the Eastern traditional medicine. Objective: To evaluate the analgesic and acute anti-inflammatory effects of liquid extract VK2. Subjects and method: The trial was performed on white mice (18-22 g body weight) and albino rats (120 +/- 20 g body weight). These animals were healthy. The prescribed amount of VK2 doses were 27.5 g and 55 g per kg body weight of the mice, 19.25 g and 38.5 g per kg body weight of the rats. Results: The liquid extract of VK2 doses had analgesic effect on acetic acide and themal-induced pain in the mice. The liquid extract of VK2 doses had also acute anti-inflammatory effect through inhibiting carrageenine-induced edema in the hind paw. Conclusion: VK2 had analgesic and anti-inflammatory effects on experimental animals.
VK2
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analgesia
;
anti-inflammatory
8.Circulation of influenza B lineages in northern Viet Nam, 2007–2014
Thi Thanh Le ; Thu Hang Pham ; Thi Hien Pham ; Le Khanh Hang Nguyen ; Co Thach Nguyen ; Vu Mai Phuong Hoang ; Thu Huong Tran ; Vu Son Nguyen ; Huong Giang Ngo ; Quynh Mai Le
Western Pacific Surveillance and Response 2015;6(4):17-23
9.The study on vertical transmision of Nam Dinh Virus and Coltivirus group B from Culex quinque fasciatus in Can Tho Province
Nga Thi Thanh Phan ; Loan Thi Kim Huynh ; Trang Minh Bui ; Quyen Do Pham ; Hoang Viet Nguyen ; Hien Thi Thu Le ; Thu Thi Viet Ho ; Thao Phuong Huynh ; Huong Thi Que Vu
Journal of Preventive Medicine 2007;17(3):11-15
Background:\r\n', u'There are two virus known as Nam Dinh Virus, and Colti group B be found in Viet Nam. These viruses have appeared in the South, the Middle and the Highland. They haven\u2019t been reported in the Southern provinces and Can Thoas well. \r\n', u'Objectives: \r\n', u'To identify the circulation of Nam Dinh virus strain, and coltivirus group B strain in Can Tho, Southern Viet Nam, and their existence in nature.\r\n', u'Subjects and method: \r\n', u'Thirty-four mosquito samples (7, 453 individual mosquitoes) from Culex quinque faciatus and Culex pseudovishnui were collected in Can Tho provice, southern Vietnam 2005.\r\n', u'Isolatingviruses on Aedes albopictuc clone C6/36, Vero cells, and using PT- PCR and ELISA Sandwich for identification. \r\n', u'Results:\r\n', u'2 Nam Dinh virus strains, 2 coltivirus group B strains and 1 flavivirus strain (insect flavivirus) were isolated from Culex quinque faciatus, and no virus was isolated from Culex pseudovishnui.\r\n', u'Conclusion: \r\n', u'The identification of the transmission of Nam dinh Virus, and coltivirus group B in Can Tho province by isolating virus from Culex quinque faciatus has shown the evidence for natural vertical transmission of these viruses.\r\n', u'
Viruses
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Coltivirus
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Flavivirus
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Arboviruses
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Culex
;
10.Characterization and Immunopotentiating Effects of the Glycoprotein Isolated from Dioscorea Batatas.
Pham Thi Thu HUONG ; Chan Ho LEE ; Mei Hong LI ; Min Young LEE ; Joon Ki KIM ; Sun Mee LEE ; Jong Heum SEON ; Dong Cheol LEE ; Young Jin JEON
The Korean Journal of Physiology and Pharmacology 2011;15(2):101-106
We demonstrate that glycoprotein isolated from Dioscorea batatas (GDB) has immunostimulatory effects including macrophage activation. Analysis of infiltration of inflammatory cells into peritoneal cavity showed GDB treatment significantly increased the recruitment of macrophages, lymphocytes, neutrophils, and monocytes into the peritoneal cavity. Treatment of spleen cells isolated from C57BL/6 mice with GDB significantly increased the proliferation of B cells and T cells induced by LPS and ConA, respectively. Treatment with GDB significantly increased the cytolytic capacity of NK cells and macrophages against YAC-1 and B16 cells, respectively. In order to further confirm and investigate the mechanism of GDB on macrophage activation, we analyzed the effects of GDB on the cytokine expression including iNOS, IL-1beta, and TNF-alpha in mouse macrophage cell line, RAW 264.7 cells. RT-PCR and ELISA showed that GDB increased the expression of IL-1beta, and TNF-alpha, whereas iNOS was not induced by GDB. Collectively, this series of experiments indicates that GDB stimulates immune system including macrophage activation.
Animals
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B-Lymphocytes
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Cell Line
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Dioscorea
;
Enzyme-Linked Immunosorbent Assay
;
Glycoproteins
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Immune System
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Killer Cells, Natural
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Lymphocytes
;
Macrophage Activation
;
Macrophages
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Mice
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Monocytes
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Neutrophils
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Peritoneal Cavity
;
Spleen
;
T-Lymphocytes
;
Tumor Necrosis Factor-alpha