1.To compare the efficacy of classic method of treatment and intervasculary He-Ne therapy in combining with the classic method for acute myocardiac infartus
Journal of Practical Medicine 2003;439(1):82-87
113 patients with myocardiac infarctus, admitted from Jan 2000 to November 2002, among them 51-i.e 45,1% patients (group 1) were benefited by classic method of treatment, 41 patients i.e 36,3% (group 2) by classic method combining fibrinolyse medicaments. It appears that in subject of group 2 hyprotension/fluctation, heart failure, pulmonary edema less developed than group 1. It appears that post-treatment dysrythmia in group 2 less and mildly developed than group 1. The difference of two groups on the rate of clinical arterial unclog was not considerable (33,3% - 34,1%) mainly because of heart failure. It appears that in group 2 the rate of death is lower and heart failure after infarctus was not commonly reported. This is a safe, simple and easy treament without adverse reaction
Myocarditis
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Therapeutics
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Myocardial Infarction
2.Economic Burden of Chronic Obstructive Pulmonary Disease: A Systematic Review
Hai Quang PHAM ; Kiet Huy Tuan PHAM ; Giang Hai HA ; Tin Trung PHAM ; Hien Thi NGUYEN ; Trang Huyen Thi NGUYEN ; Jin-Kyoung OH
Tuberculosis and Respiratory Diseases 2024;87(3):234-251
Globally, providing evidence on the economic burden of chronic obstructive pulmonary disease (COPD) is becoming essential as it assists the health authorities to efficiently allocate resources. This study aimed to summarize the literature on economic burden evidence for COPD from 1990 to 2019. This study examined the economic burden of COPD through a systematic review of studies from 1990 to 2019. A search was done in online databases, including Web of Science, PubMed/Medline, Scopus, and the Cochrane Library. After screening 12,734 studies, 43 articles that met the inclusion criteria were identified. General study information and data on direct, indirect, and intangible costs were extracted and converted to 2018 international dollars (Int$). Findings revealed that the total direct costs ranged from Int$ 52.08 (India) to Int$ 13,776.33 (Canada) across 16 studies, with drug costs rannging from Int$ 70.07 (Vietnam) to Int$ 8,706.9 (China) in 11 studies. Eight studies explored indirect costs, while one highlighted caregivers’ direct costs at approximately Int$ 1,207.8 (Greece). This study underscores the limited research on COPD caregivers’ economic burdens, particularly in developing countries, emphasizing the importance of increased research support, particularly in high-resource settings. This study provides information about the demographics and economic burden of COPD from 1990 to 2019. More strategies to reduce the frequency of hospital admissions and acute care services should be implemented to improve the quality of COPD patients’ lives and reduce the disease’s rising economic burden.
3.Zika preparedness and response in Viet Nam
Dong T Nguyen ; Hung T Do ; Huy X Le ; Nghia T Le ; Mai Q Vien ; Trieu B Nguyen ; Lan T Phan ; Thuong V Nguyen ; Quang C Luong ; Hung C Phan ; Hai T Diep ; Quang D Pham ; Thinh V Nguyen ; Loan KT Huynh ; Dung CT Nguyen ; Hang TT Pham ; Khanh KH Ly ; Huong NLT Tran ; Phu D Tran ; Tan Q Dang ; Hung Pham ; Long N Vu ; Anthony Mounts ; S Arunmozhi Balajee ; Leisha D Nolen
Western Pacific Surveillance and Response 2018;9(2):1-3
This article describes Viet Nam Ministry of Health’s (VMoH) activities to prepare for and respond to the threat Zika virus (ZIKV), including the adaptation of existing surveillance systems to encompass ZIKV surveillance.
4.Re-positive testing, clinical evolution and clearance of infection: results from COVID-19 cases in isolation in Viet Nam
Ngoc-Anh Hoang ; Thai Quang Pham ; Ha-Linh Quach ; Khanh Cong Nguyen ; Samantha Colquhoun ; Stephen Lambert ; Huy Luong Duong ; Dai Quang Tran ; Cong Dinh Phung ; Nhu Duong Tran ; Duy Nghia Ngu ; Anh Tu Tran ; Hue Bich Thi Nguyen ; Duc-Anh Dang ; Florian Vogt
Western Pacific Surveillance and Response 2021;12(4):82-92
Objectives:
Asymptomatic infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and test re-positivity after a negative test have raised concerns about the ability to effectively control the coronavirus disease 2019 (COVID-19) pandemic. We aimed to investigate the prevalence of COVID-19 asymptomatic and pre-symptomatic infections during the second wave of COVID-19 in Viet Nam, and to better understand the duration of SARS-CoV-2 infection and the dynamics between the evolution of clinical symptoms and SARS-CoV-2 test positivity among confirmed COVID-19 cases.
Methods:
We conducted a cohort analysis on the first 50 confirmed cases during the second COVID-19 wave in Viet Nam using clinical, laboratory and epidemiological data collected from 9 March to 30 April 2020. Kaplan-Meier estimates were used to assess time to clearance of SARS-CoV-2 infection, and log-rank tests were used to explore factors related to time to SARS-CoV-2 infection clearance.
Results:
Most cases (58%) had no typical signs or symptoms of COVID-19 at the time of diagnosis. Ten cases (20%) were re-positive for SARS-CoV-2 during infection. Eight cases (16%) experienced COVID-19 symptoms after testing negative for SARS-CoV-2. The median duration from symptom onset until clearance of infection was 14 days (range: 6–31); it was longer in re-positive and older patients and those with pre-existing conditions.
Conclusion
Asymptomatic and pre-symptomatic infections were common during the second wave of COVID-19 in Viet Nam. Re-positivity was frequent during hospitalization and led to a long duration of SARS-CoV-2 infection.
5.Within-household SARS-CoV-2 transmission and vaccine effectiveness in the first three COVID-19 school outbreaks in northern Viet Nam, September–December 2021
Trang Thu Vu ; Tu Huy Ngo ; Khanh Cong Nguyen ; Vu Thi Lan ; Cu Thi Bich Hanh ; Le Hong Son ; Huyen Thi Nguyen ; Hien Thi Nguyen ; Nghia Duy Ngu ; Duong Nhu Tran ; Duc-Anh Dang ; Florian Vogt ; Thai Quang Pham
Western Pacific Surveillance and Response 2024;15(3):19-30
Objective: The risk of transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from schoolchildren to their household and the protective effects of vaccination in these settings remain poorly understood. We assessed the transmission dynamics of schoolchildren with SARS-CoV-2 within their households and the protective effects of coronavirus disease (COVID-19) vaccination among household members in Viet Nam.
Methods: We estimated the attack rate, vaccine effectiveness and adjusted risk ratio (aRR) of factors associated with SARS-CoV-2 transmission to household contacts of children confirmed to have COVID-19 who attended three schools in Ha Nam, Phu Tho and Thanh Hoa provinces between September and December 2021 using multivariable regression with household-level random effects.
Results: This retrospective cohort study included 157 children infected with SARS-CoV-2 and their 540 household contacts. The attack rate among household contacts was 24.6% (133/540). Overall, vaccine effectiveness among household contacts was 39% (95% confidence interval [CI]: -1 to -63), higher among males than females and higher in adults aged >40 years. COVID-19 transmission was greater among female household contacts compared with males (aRR: 1.35, 95% CI: 0.94 to 1.95), although not statistically significant, and highest among those aged 19–39 years (aRR: 2.51, 95% CI: 1.50 to 4.21). Fully vaccinated household contacts had significantly lower infection risk (aRR: 0.46, 95% CI: 0.26 to 0.84).
Discussion: We found substantial onward transmission of SARS-CoV-2 from schoolchildren to household members, and older people were more likely to be protected by vaccination. We recommend that schoolchildren and all household members living with schoolchildren receive at least two doses of a COVID-19 vaccine. Recognizing the role of schoolchildren in the onward transmission of COVID-19 is an important lesson learned by Viet Nam that can help not only in managing other outbreaks but also in protecting schoolchildren by predicting the progress of the outbreak and preparing for a timely response.