Experiments were undertaken on normal subjects at the age of 19-44 years. Pain threshold were measured by Analgesymeter (Made in Ugobasile-Italy) in 60 subjects before and after 30 minutes of PC6 EA. Amplitude and latency of Hoffman wave of 30 males was investigated before and after 30 minutes of PC6 EA. EA parameters were set in 2Hz, 4-5 volts. The following results were shown: (1) PC6 EA could elevate pain threshold in most subjects (p< 0.01); After acupuncture, pain threshold is more increase in women comparing to men (p<0.05). Electric acupunture at Neiguan inhibit H reflex by reduce its amplitude and last the latency of this wave (p<0.05). thse results suggested that pain reduce mechanism of electric accupunture could ralate to the role of nervous system.
Pain Threshold, Electroacupuncture

120 subjects were selected and divided into two groups to study resistance and intensity of 12 couples of Yuan point. Case group involved 60 subjects aged>50, suffered from duodenal ulcer (30 males, 30 females). Control group involved 60 subjects aged>50 (30 males, 30 females) without this condition. The results showed that: there were difference in resistance and intensity of Tai chong point (Iiv3) of the left and right body in both male and female (p<0.05-0.01), but not in the other ones. Resistance of 12 couples of Yuan point of duodenal-ulcer group was markedly higther whereas intensity was lower in comparing with control group, especially in Da ling TH7, Chong yang St42, Tai bai Sp3. Hegu Ll4. Yang chi HC4.
Peptic Ulcer, Acupuncture Points

Comparision of analgesia and side effects in spinal anesthesia administered by bupivacaine combined with fentanyl in 66 patients with indicated abdominal hysterectomy in the Institute of Military Medicine No.103, from February to July, 2003. The results showed that: spinal anesthesia and the safe in surgeries have agained with the same dose 0.18mg/kg bupivacaine and 25mcg fentanyl at spinal interspace L2-3 and L3-4. However, spinal anesthesia was administered at the interspace L2-3 difference L3-4: onset time of sensory blockade at the T6 is faster, analgesia level after 20mins is higher, hemodynamic changing are faster and more serious
Anesthesia, Spinal ; Analgesia/adverse effects ; Surgery

The study was carried out in Hoankiem and Socson district in Hanoi city. In each area, 160 women were selected and divided in to 4 groups: the menopause of 5 years, >5-10 years, >10 years and groups of 25-39 year old. Vein blood were taken for the measurement of serum estradiol, FSH, LH concentration. The results showed that: Serum estradiol concentration significantly decreased in postmenopausal women compared with women at reproductive age and no difference between the menopausal groups. These values in Hoankiem women were higher than that in Socson women, specially with the menopause of 5 years. Serum FSH and LH concentration significantly increased in the menopausal period. While FSH concentration did not change during menopause time, LH concentration showed a tendency to decrease. Serum FSH concentration in the Hoankiem women was higher than this in Socson ones whereas serum concentration was lower
Menopause ; Menotropins ; serum ; women

23 healthy male students from 19-26 of age were studied on the change of serum concentration of cortisol, ACTH, catecholamin, acetylchollin and beta-endorphin after 30 minutes Hegu electroacupuncture. The results show that: there is increase of catecholamin and acetylcholin concentration, decrease of cortisol concentration after exact Hegu electro- acupuncture.- No significant difference of ACTH and beta-endorphin concentration is detected before and after Hegu electro- acupuncture.- Above parameters do not change after outside the Hegu electro- acupuncture exept cortisol concentration that is markly lower.
Acupuncture ; hormones ; Neurotransmitter Agents

Objectives: The association between body composition parameters and peak bone mineral density is not well documented. The aim of this study is to assess the relative contributions of lean mass and fat mass on peak bone mineral density (BMD). Methods: The study involved 416 women and 334 men aged between 20 and 30 years who were participants in the population-based Vietnam Osteoporosis Study. Whole body composition parameters (eg, fat mass and lean mass) and BMD at the lumbar spine and femoral neck were measured by dual-energy X-ray absorptiometry. The association between lean mass and fat mass and BMD was analyzed by the linear regression model using the Least Absolute Shrinkage and Selection Operator (LASSO). Results: Peak BMD in men was higher than women, and the difference was more pronounced at the femoral neck (average difference: 0.123 g/㎠; 95% confidence interval [CI] 0.105–0.141 g/㎠) than at the lumbar spine (average difference 0.019 g/㎠; 95% CI, 0.005–0.036 g/㎠). Results of LASSO regression indicated that lean mass was the only predictor of BMD for either men or women. Each kilogram increase in lean mass was associated with ∼0.01 g/㎠ increase in BMD. Lean mass alone explained 16% and 36% of variation in lumbar spine and femoral neck BMD, respectively. Conclusions Lean mass, not fat mass, is the main determinant of peak bone mineral density. This finding implies that good physical activity during adulthood can contribute to the maximization of peak bone mass during adulthood.

Objectives: The association between body composition parameters and peak bone mineral density is not well documented. The aim of this study is to assess the relative contributions of lean mass and fat mass on peak bone mineral density (BMD). Methods: The study involved 416 women and 334 men aged between 20 and 30 years who were participants in the population-based Vietnam Osteoporosis Study. Whole body composition parameters (eg, fat mass and lean mass) and BMD at the lumbar spine and femoral neck were measured by dual-energy X-ray absorptiometry. The association between lean mass and fat mass and BMD was analyzed by the linear regression model using the Least Absolute Shrinkage and Selection Operator (LASSO). Results: Peak BMD in men was higher than women, and the difference was more pronounced at the femoral neck (average difference: 0.123 g/㎠; 95% confidence interval [CI] 0.105–0.141 g/㎠) than at the lumbar spine (average difference 0.019 g/㎠; 95% CI, 0.005–0.036 g/㎠). Results of LASSO regression indicated that lean mass was the only predictor of BMD for either men or women. Each kilogram increase in lean mass was associated with ∼0.01 g/㎠ increase in BMD. Lean mass alone explained 16% and 36% of variation in lumbar spine and femoral neck BMD, respectively. Conclusions Lean mass, not fat mass, is the main determinant of peak bone mineral density. This finding implies that good physical activity during adulthood can contribute to the maximization of peak bone mass during adulthood.

OBJECTIVES: Osteoporosis and fracture impose a significant health care burden on the contemporary populations in developing countries. The Vietnam Osteoporosis Study (VOS) sought to assess the burden of osteoporosis and its comorbidities in men and women. METHODS: The study was designed as a population-based family investigation in which families were randomly recruited from Ho Chi Minh City, Vietnam. Individuals were assessed for bone health, including bone mineral density (BMD) and body composition and trabecular and cortical bone properties by pQCT (peripheral quantitative computed tomography). Fasting blood samples were obtained for the analysis of plasma glucose, glycosylated hemoglobin, and bone turnover markers. Genomic DNA extraction from whole blood samples for further genetic and genomic analyses. RESULTS: We have recruited more than 4157 individuals from 817 families. The average age of participants was 51, with approximately 45% of the individuals aged 50 years and older. Approximately 3% of participants were obese (body mass index ≥ 30 kg/m²), and 21% were overweight. Notably, 11% of participants aged 40 years and older were diabetic. Among those aged 50 years and older, approximately 14% of women and 5% of men had osteoporosis (i.e., femoral neck BMD T-scores ≤−2.5). There were modest correlations between volumetric BMD and areal BMD. CONCLUSIONS: VOS is a major bone research project in Vietnam aimed at comprehensively documenting the burden osteoporosis, its co-occurrence of chronic diseases, and their underlying etiologies. The Study will make important contributions to the literature of bone health worldwide.
Blood Glucose ; Body Composition ; Bone Density ; Bone Remodeling ; Chronic Disease ; Comorbidity ; Delivery of Health Care ; Developing Countries ; DNA ; Fasting ; Female ; Femur Neck ; Hemoglobin A, Glycosylated ; Humans ; Male ; Muscle Strength ; Osteoporosis* ; Overweight ; Sarcopenia ; Vietnam*

Aims: The objective of the study was to isolate bacteriophages and conduct a comprehensive analysis of their potential against Xanthomonas oryzae pv. oryzae (Xoo) strains in the Mekong Delta, Vietnam. Methodology and results: Twelve Xoo strains were isolated from rice fields located in the Mekong Delta, Vietnam. Among these strains, three strains Xoo L019, L020 and L024, showed the highest disease index of bacterial blight. Four phages specific to Xoo were isolated from soil, water and leaf samples, and their morphologies were determined. In a test against 12 Xoo strains, phage L541, MLA23 or W41 could infect 10 of the 12 Xoo strains, while phage LBH01 could infect 8 of the 12 Xoo strains. The stability of the phages to pH, organic solvents, UV-A and UV-B was also evaluated. Conclusion, significance and impact of study The initial characterization of the phages indicates their potential as biocontrol agents against bacterial blight in rice. The study is one of the very first studies about Xoo phages in rice in Vietnam.

Background: Avian influenza (AI) is a contagious disease that causes illness and death in poultry and humans. High pathogenicity AI (HPAI) H5N6 outbreaks commonly occur in Quang Ninh province bordering China. In June 2021, the first HPAI H5N8 outbreak occurred at a Quang Ninh chicken farm. Objectives: This study examined the risk factors associated with HPAI H5N6 and H5N8 outbreaks in Quang Ninh. Methods: A retrospective case-control study was conducted in Quang Ninh from Nov 2021 to Jan 2022. The cases were households with susceptible poultry with two or more clinical signs and tested positive by real-time reverse transcription polymerase chain reaction. The controls were households in the same village as the cases but did not show clinical symptoms of the disease. Logistic regression models were constructed to assess the risk factors associated with HPAI outbreaks at the household level. Results: There were 38 cases with H5N6 clade 2.3.4.4h viruses (n = 35) and H5N8 clade 2.3.4.4b viruses (n = 3). Compared to the 112 controls, raising poultry in uncovered or partially covered ponds (odds ratio [OR], 7.52; 95% confidence interval [CI], 1.44–39.27), poultry traders visiting the farm (OR, 8.66; 95% CI, 2.7–27.69), farms with 50–2,000 birds (OR, 3.00; 95% CI, 1.06–8-51), and farms with ≥ 2,000 birds (OR, 11.35; 95% CI, 3.07–41.94) were significantly associated with HPAI outbreaks. Conclusions Combining biosecurity measures, such as restricting visitor entry and vaccination in farms with more than 50 birds, can enhance the control and prevention of HPAI in Quang Ninh and its spread across borders.