Blastomeres; Serum; Pathological Conditions, Anatomical; Chorionic Gonadotropin The group 1 of 75 cases of post molar evacuation and the group 2 of 292 cases of gestational trophoblastic tumors (GTT) were followed up until beta-hCG level serum, determined by IMX, reaches the threshold of < 5 IU/l, there was not any complication after 2 years. There were 7.5% recurrents cases in GTT group, in some cases, beta-hCG reaches 0 UI/l. In the recurrent group, the rate of resistance to the treatment got to 40%, and the rate of resistance to single chemotherapy by MTX got to 30%. 50% of recurrent patients have had uterine histological exams with 36% choriocarcinoma, 4.5% invasive molar
Blastomeres ; Serum ; Pathological Conditions, Anatomical ; Chorionic Gonadotropin

94 women with hydraform mole pregnancy were studied in the Institute of Protection of Mother and Newborn from March 1999 to March 2001. Their beta-hCG levels were evaluated weekly before and after abolition of hydatoform mole, the results were dramatically different. After abolition, the monitoring of beta-hCG curve to detect the mast blastocyte tumors reached a sensivity of 79% and a specificity of 100%. Among the group having complications, the bleeding more prolonged than the groups of no complication of mast blastocyte tumor. Beta-hCG blood level was in safe threshold.
Pregnancy ; Women ; Pregnant Women ; serum ; Chorionic Gonadotropin

292 patients with gestational trophoblastic tumor diagnosed by beta-hCG assay were treated with chemotherapy. The rate of hysterectomy performed before chemotherapy is higher than that during and after chemotherapy. This rate is higher in the group of metastasis subjects than in no metastasis subject group. The rate of single chemotherapy resistance of hysterectomy group is lower in the case of hysterectomy performed before chemotherapy than in the case during and after chemotherapy
Hysterectomy ; Gestational Trophoblastic Neoplasms ; Patients ; Therapeutics

292 patients with mast blastocytoma who were diagnosed after hydatiform pregnancy, after birth and post pregnancy basing on the examinations of beta-HCG, of matastasis and of anapathology, treated till beta HCG < 5 UI/l. According to US classification, the age of the group 1 (non metastasis ligh mast blastocytoma) is younger than group 2 (metastasis severe mast blastocytoma) and in the group 2 the duration from termination of pregnancy to detection of the condition is longer than group 1. In the group of mast blastocytoma of severe prognosis there are an uterus damage of chorion carcinoma, an invasive hydatiform pregnancy. The simple resistance to chemiotherapy is more dramatical in the group 2 than the group 1
Pregnancy ; Pregnant Women ; Women ; Prognosis