1.The relation of beta-hCG levels before the artificial abortion and fetal age and the number of removed tissue of hydatiform mole
Journal of Practical Medicine 2003;425(5):50-51
Study conducted on 57 cases of complete hydatiform mole, with the average fetal age of 13.5641.04 weeks (lowest 6 weeks, highest 20.5 weeks) beta-hCG average level 1158656.16246627.71 IU/l (min 79072 IU/l, max 5474400 IU/l), volume of removed tissue – min 100 ml, max 2500 ml). Results showed that the correlation between preevacuation beta-hCG level and removed tissue volume is higher than the correlation between gestational age and the number of evacuated mole. Between preevacuated beta-hCG level and gestational age the correlation is not valuable
Abortion, Legal
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Gestational Age
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Pregnant Women
2.Within-household SARS-CoV-2 transmission and vaccine effectiveness in the first three COVID-19 school outbreaks in northern Viet Nam, September–December 2021
Trang Thu Vu ; Tu Huy Ngo ; Khanh Cong Nguyen ; Vu Thi Lan ; Cu Thi Bich Hanh ; Le Hong Son ; Huyen Thi Nguyen ; Hien Thi Nguyen ; Nghia Duy Ngu ; Duong Nhu Tran ; Duc-Anh Dang ; Florian Vogt ; Thai Quang Pham
Western Pacific Surveillance and Response 2024;15(3):19-30
Objective: The risk of transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from schoolchildren to their household and the protective effects of vaccination in these settings remain poorly understood. We assessed the transmission dynamics of schoolchildren with SARS-CoV-2 within their households and the protective effects of coronavirus disease (COVID-19) vaccination among household members in Viet Nam.
Methods: We estimated the attack rate, vaccine effectiveness and adjusted risk ratio (aRR) of factors associated with SARS-CoV-2 transmission to household contacts of children confirmed to have COVID-19 who attended three schools in Ha Nam, Phu Tho and Thanh Hoa provinces between September and December 2021 using multivariable regression with household-level random effects.
Results: This retrospective cohort study included 157 children infected with SARS-CoV-2 and their 540 household contacts. The attack rate among household contacts was 24.6% (133/540). Overall, vaccine effectiveness among household contacts was 39% (95% confidence interval [CI]: -1 to -63), higher among males than females and higher in adults aged >40 years. COVID-19 transmission was greater among female household contacts compared with males (aRR: 1.35, 95% CI: 0.94 to 1.95), although not statistically significant, and highest among those aged 19–39 years (aRR: 2.51, 95% CI: 1.50 to 4.21). Fully vaccinated household contacts had significantly lower infection risk (aRR: 0.46, 95% CI: 0.26 to 0.84).
Discussion: We found substantial onward transmission of SARS-CoV-2 from schoolchildren to household members, and older people were more likely to be protected by vaccination. We recommend that schoolchildren and all household members living with schoolchildren receive at least two doses of a COVID-19 vaccine. Recognizing the role of schoolchildren in the onward transmission of COVID-19 is an important lesson learned by Viet Nam that can help not only in managing other outbreaks but also in protecting schoolchildren by predicting the progress of the outbreak and preparing for a timely response.