2.A Case of Peutz-Jeghers Syndrome with Intraductal Papillary Mucinous Carcinoma of Pancreas.
Pyung Gohn GOH ; Hee Seok MOON ; Jae Kyu SUNG ; Hyun Yong JEONG ; Kyu Sang SONG
The Korean Journal of Gastroenterology 2010;55(1):73-77
Peutz-Jeghers syndrome (PJS), which is characterized by multiple hamartomatous polyps of the gastrointestinal tract and mucocutaneous pigmentation, is a rare autosomal dominant disease. This syndrome is often represented as a surgical emergency with complications of the polyps such as intussusception, small bowel obstruction, bleeding, and volvulus. In particular, many studies have reported that patients with this syndrome have a high risk of gastrointestinal or extragastrointestinal malignancy including gastric, duodenal, jejunal, ileal, and colonic carcinoma as well as malignancies involving other organs such as the gallbladder, biliary tract, pancreas, tonsils, breast, and reproductive system. However, there are few reported cases of an association of this syndrome with extraintestinal malignancy. In addition to that, there is no reported case of this syndrome with malignant tumor or intraductal papillary mucinous tumor of pancreas in Korea. We experienced a case of PJS accompanying intraductal papillary mucinous carcinoma of the pancreas, therefore we report this case with literatures reviewed.
Adenocarcinoma, Mucinous/*diagnosis/pathology/secondary
;
Carcinoma, Papillary/*diagnosis/pathology/secondary
;
Humans
;
Intussusception/surgery
;
Jejunum/surgery
;
Male
;
Middle Aged
;
Pancreatic Neoplasms/complications/*diagnosis/pathology
;
Peutz-Jeghers Syndrome/complications/*diagnosis
;
Tomography, X-Ray Computed
3.A Case of Peutz-Jeghers Syndrome with Intraductal Papillary Mucinous Carcinoma of Pancreas.
Pyung Gohn GOH ; Hee Seok MOON ; Jae Kyu SUNG ; Hyun Yong JEONG ; Kyu Sang SONG
The Korean Journal of Gastroenterology 2010;55(1):73-77
Peutz-Jeghers syndrome (PJS), which is characterized by multiple hamartomatous polyps of the gastrointestinal tract and mucocutaneous pigmentation, is a rare autosomal dominant disease. This syndrome is often represented as a surgical emergency with complications of the polyps such as intussusception, small bowel obstruction, bleeding, and volvulus. In particular, many studies have reported that patients with this syndrome have a high risk of gastrointestinal or extragastrointestinal malignancy including gastric, duodenal, jejunal, ileal, and colonic carcinoma as well as malignancies involving other organs such as the gallbladder, biliary tract, pancreas, tonsils, breast, and reproductive system. However, there are few reported cases of an association of this syndrome with extraintestinal malignancy. In addition to that, there is no reported case of this syndrome with malignant tumor or intraductal papillary mucinous tumor of pancreas in Korea. We experienced a case of PJS accompanying intraductal papillary mucinous carcinoma of the pancreas, therefore we report this case with literatures reviewed.
Adenocarcinoma, Mucinous/*diagnosis/pathology/secondary
;
Carcinoma, Papillary/*diagnosis/pathology/secondary
;
Humans
;
Intussusception/surgery
;
Jejunum/surgery
;
Male
;
Middle Aged
;
Pancreatic Neoplasms/complications/*diagnosis/pathology
;
Peutz-Jeghers Syndrome/complications/*diagnosis
;
Tomography, X-Ray Computed
4.A Case of Crohn's Disease Accompanied by Peutz-Jeghers Syndrome.
Yoo Jin UM ; Sun Moon KIM ; Jin Sil PYO ; Joo Ah LEE ; Hoon Sup KOO ; Kyu Chan HUH
The Korean Journal of Gastroenterology 2013;62(4):243-247
Peutz-Jeghers syndrome is an autosomal dominant inherited disorder characterized by multiple gastrointestinal hamartomatous polyps and mucocutaneous pigmentation. Peutz-Jeghers syndrome has an incidence of approximately 1 in 25,000 to 300,000 births. Crohn's disease is a chronic inflammatory bowel disease that typically manifests as regional enteritis with its incidence ranging from 3.1 to 14.6 cases per 100,000 person-years in North America. Herein, we report a case of a 30-year-old male patient who had both Peutz-Jeghers syndrome and Crohn's disease. We believe that this is the first case in Korea and the second report in the English literatures on Peutz-Jeghers syndrome coincidentally accompanied by Crohn's disease.
Adult
;
Crohn Disease/complications/*diagnosis/pathology
;
Endoscopy, Gastrointestinal
;
Humans
;
Intestinal Obstruction/etiology
;
Intestinal Perforation/etiology
;
Intestinal Polyps/pathology/surgery
;
Male
;
Peutz-Jeghers Syndrome/complications/*diagnosis/genetics
;
Protein-Serine-Threonine Kinases/genetics
5.Peutz-Jeghers syndrome complicated by cervical adenoma malignum and ovarian sex cord tumor with annular tubules: report of a case.
Chinese Journal of Pathology 2006;35(12):761-762
Adenocarcinoma
;
complications
;
metabolism
;
pathology
;
Adult
;
Carcinoembryonic Antigen
;
metabolism
;
Diagnosis, Differential
;
Female
;
Humans
;
Immunohistochemistry
;
Ki-67 Antigen
;
metabolism
;
Ovarian Neoplasms
;
complications
;
metabolism
;
pathology
;
Peutz-Jeghers Syndrome
;
complications
;
metabolism
;
pathology
;
Proliferating Cell Nuclear Antigen
;
metabolism
;
Sex Cord-Gonadal Stromal Tumors
;
complications
;
metabolism
;
pathology
;
Uterine Cervical Neoplasms
;
complications
;
metabolism
;
pathology