1.A Case of Crohn's Disease Accompanied by Peutz-Jeghers Syndrome.
Yoo Jin UM ; Sun Moon KIM ; Jin Sil PYO ; Joo Ah LEE ; Hoon Sup KOO ; Kyu Chan HUH
The Korean Journal of Gastroenterology 2013;62(4):243-247
Peutz-Jeghers syndrome is an autosomal dominant inherited disorder characterized by multiple gastrointestinal hamartomatous polyps and mucocutaneous pigmentation. Peutz-Jeghers syndrome has an incidence of approximately 1 in 25,000 to 300,000 births. Crohn's disease is a chronic inflammatory bowel disease that typically manifests as regional enteritis with its incidence ranging from 3.1 to 14.6 cases per 100,000 person-years in North America. Herein, we report a case of a 30-year-old male patient who had both Peutz-Jeghers syndrome and Crohn's disease. We believe that this is the first case in Korea and the second report in the English literatures on Peutz-Jeghers syndrome coincidentally accompanied by Crohn's disease.
Adult
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Crohn Disease/complications/*diagnosis/pathology
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Endoscopy, Gastrointestinal
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Humans
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Intestinal Obstruction/etiology
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Intestinal Perforation/etiology
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Intestinal Polyps/pathology/surgery
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Male
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Peutz-Jeghers Syndrome/complications/*diagnosis/genetics
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Protein-Serine-Threonine Kinases/genetics