Mesotherapy is one of skin rejuvenation methods and known to be effective for anti-aging, cosmetic treatment, and improvement of obesity. Furthermore, the side effect of mesotherapy has been known to be very little, therefore, it has been used widely. Because of these reasons, complication of mesotherapy has been disregarded. A 32-year-old woman visited a private clinic for improvement of obesity. The patient had placenta injection with aminophylline, lidocaine and epinephrine on abdomen for several times and she did not have any symptoms. However, placenta injection was carried out at the last time with aminophylline, lidocaine, epinephrine and dehydrated alcohol. Four days later, abdominal partial necrosis was developed. And she was refered to our department. Wound of the abdomen had eschar formation and reddish color change. So, debridement of necrotic skin, and immediate reconstruction using flap and cosmetic abdominoplasty were done immediately, and the patient was satisfied with results. Based on various circumstances, we concluded that one of the etiologies of necrosis might be dehydrated alcohol and epinephrine effect. The standard of materials that are mixed in mesotherapy has not yet been established. In fact, the safety of additives has not yet been verified. Therefore, more studies on the standard materials and safety are needed.
Female ; Humans

PURPOSE: Many researches about various surgical method for blepharoptosis have already been introduced. But researches for complications after blepharoptosis correction is relatively insufficient. So, this study was performed to recognize common complications that arise depending on the severity of blepharoptosis, levator function and surgical method. METHODS: 250 patients who have undergone surgical treatment for blepharoptosis from 1987 to 2006 were analyzed in this study. Patients were categorized according to severity of blepharoptosis, levator function and surgical method that has been used. Complications after blepharoptosis correction were analyzed. RESULT: There occurred complications in 64 patients. The specifics are as following; undercorrection 22, asymmetry 13, overcorrection 12, lagophthalmos 4, abnormal eyelid contour 4, exposure keratitis 3, ectropion 2, inclusion cyst 2, infection 1 and conjunctival prolapse 1. Among above patients, 3 patients had two kinds of complications. 21 patients underwent secondary surgery due to complication. CONCLUSION: Evaluating the outcomes of the secondary surgery, the early correction was better than the late correction. The most of the complications were recovered through conservative and surgical treatments. The most of the complications (47 patients) were undercorrection, asymmetry, overcorrection and took 73.4% of the total complications. As the blepharoptosis became severe or levator function became poorer, the rate of complications became higher. According to the operation methods, most of the complications occurred in levator operation, frontalis transfer and OOM flap.
Blepharoptosis ; Ectropion ; Eyelids ; Humans ; Keratitis ; Postoperative Complications ; Prolapse