1.Peripheral neuroepithelioma of the kidney.
Ki Whang KIM ; Doo Hoe HA ; Woo Hee JUNG
Journal of Korean Medical Science 1995;10(6):457-461
Peripheral neuroepithelioma is a rare tumor, comprising less than 1% of all soft tissue malignancies arising from the peripheral nonautonomic nervous system. Most peripheral neuroepitheliomas reported were located in the extremities, thoraco-pulmonary region, and pelvic areas, and as many as 30% of cases were associated with peripheral nerve. We report one case of peripheral neuroepithelioma arising in the kidney, mimicking renal cell carcinoma on the CT scan.
Adult
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Case Report
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Female
;
Human
;
Kidney Neoplasms/*pathology
;
Neuroectodermal Tumors, Primitive, Peripheral/*pathology
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Peripheral Nervous System Diseases/*pathology
2.Macrodactylism Associated with Neurofibroma of the Median Nerve: A Case Report.
In Hee CHUNG ; Nam Hyun KIM ; Il Yong CHOI
Yonsei Medical Journal 1973;14(1):49-52
A case of macrodactyly associated with neurofiborma of the median nerve, a congenital anomaly of the hand, affecting only one(left middle) finger is reported with a review of the literature. Macrodactyly which is also termed local gigantism, megalodactylism, megalodactylia, or macrodactylism in other literature, is a rare congenital malformation characterized by overgrowth of one or more fingers of hand. Macrodactyly associated with neurofibroma of the median nerve is especially rare. For this reason the following case is presented together with a review of the literature.
Adolescent
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Angiography
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Female
;
Fingers/abnormalities*
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Fingers/radiography
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Fingers/surgery
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Human
;
Korea
;
Median Nerve*/surgery
;
Neurofibroma/complications*
;
Neurofibroma/pathology
;
Neurofibroma/surgery
;
Peripheral Nervous System Neoplasms/complications*
;
Peripheral Nervous System Neoplasms/pathology
;
Peripheral Nervous System Neoplasms/surgery
;
Radial Nerve/surgery
3.Progressive atypical peripheral neuropathy following nephrectomy in a patient with renal cell carcinoma.
Journal of Korean Medical Science 1992;7(2):167-169
Peripheral neuropathy or amyotropic lateral sclerosis can be associated with renal cell carcinoma. We report a 63-year-old male patient with renal cell carcinoma who developed an atypical, progressive neuropathy after nephrectomy.
Carcinoma, Renal Cell/*complications/pathology
;
Humans
;
Kidney Neoplasms/*complications/pathology
;
Male
;
Middle Aged
;
Nephrectomy
;
Peripheral Nervous System Diseases/*etiology
5.Primary Malignant Melanoma of the Cervical Spinal Nerve Root.
Soon Chan KWON ; Seung Chul RHIM ; Deok Hee LEE ; Sung Woo ROH ; Shin Kwang KANG
Yonsei Medical Journal 2004;45(2):345-348
The authors report on a case of primary malignant melanoma of the 7th cervical spinal nerve root in a 45-year-old woman. Neuro-radiological features of this extra-dural mass were suggestive of a nerve sheath tumor. The lesion underwent total gross resection through the anterolateral approach. The patient's postoperative course was uneventful. Histopathological investigation confirmed malignant melanoma. There was no evidence of tumor recurrence or other melanotic lesions on regular follow-up examinations until the postoperative eighth month. When treating a common, benign-looking lesion of the cervical spinal nerve root, surgeons should be aware of the potential to encounter such a malignant tumor.
Cervical Vertebrae
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Female
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Human
;
Melanoma/*pathology/surgery
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Middle Aged
;
Nerve Sheath Tumors/*pathology/surgery
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Peripheral Nervous System Neoplasms/*pathology/surgery
;
Spinal Nerve Roots/*pathology
6.Primary central nervous system T-cell lymphoma in children and adolescents: a clinicopathological analysis of five cases.
Pei Zhu HU ; Heng Yan ZHANG ; Guan Nan WANG ; Wu Gan ZHAO ; Dan Dan ZHANG ; Wen Cai LI
Chinese Journal of Pathology 2023;52(1):37-42
Objective: To study the clinicopathological characteristics, and further understand primary central nervous system T-cell lymphoma (PCNSTCL) in children and adolescents. Methods: Five cases of PCNSTCL in children and adolescents were collected from December 2016 to December 2021 at the First Affiliated Hospital of Zhengzhou University. The clinicopathological characteristics, immunophenotypic, and molecular pathologic features were analyzed, and relevant literatures reviewed. Results: There were two male and three female patients with a median age of 14 years (range 11 to 18 years). There were two peripheral T-cell lymphomas, not otherwise specified, two anaplastic large cell lymphoma, ALK-positive and one NK/T cell lymphoma. Pathologically, the tumor cells showed a variable histomorphologic spectrum, including small, medium and large cells with diffuse growth pattern and perivascular accentuation. Immunohistochemistry and in situ hybridization showed CD3 expression in four cases, and CD3 was lost in one case. CD5 expression was lost in four cases and retained in one case. ALK and CD30 were expressed in two cases. One tumor expressed CD56 and Epstein-Barr virus-encoded RNA. All cases showed a cytotoxic phenotype with expression of TIA1 and granzyme B. Three cases had a high Ki-67 index (>50%). T-cell receptor (TCR) gene rearrangement was clonal in two cases. Conclusions: PCNSTCL is rare, especially in children and adolescents. The morphology of PCNSTCL is diverse. Immunohistochemistry and TCR gene rearrangement play important roles in the diagnosis.
Female
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Humans
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Male
;
Central Nervous System/pathology*
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Central Nervous System Neoplasms/pathology*
;
Epstein-Barr Virus Infections
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Herpesvirus 4, Human
;
Lymphoma, T-Cell/pathology*
;
Lymphoma, T-Cell, Peripheral/genetics*
;
Receptor Protein-Tyrosine Kinases/genetics*
;
Receptors, Antigen, T-Cell
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Child
;
Adolescent
7.Image features of two rare mediastinal tumors: schwannoma of intrathoracic phrenic nerve and clear cell chondrosarcoma of the rib.
Ting-Kai LEUNG ; Chien-Jui CHENG ; Chi-Ming LEE ; Li-Kuo SHEN ; Hung-Jung WANG ; Ya-Yen CHEN
Chinese Medical Journal 2005;118(17):1493-1496
Adult
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Bone Neoplasms
;
diagnosis
;
pathology
;
Chondrosarcoma
;
diagnosis
;
pathology
;
Female
;
Humans
;
Magnetic Resonance Imaging
;
Male
;
Mediastinal Neoplasms
;
diagnosis
;
pathology
;
Neurilemmoma
;
diagnosis
;
pathology
;
Peripheral Nervous System Neoplasms
;
diagnosis
;
pathology
;
Phrenic Nerve
;
Ribs
;
Tomography, X-Ray Computed
8.A clinicopathologic study of ten cases of cellular schwannoma.
Hua XIANG ; Qun WANG ; Jian WANG ; Xiong-zeng ZHU
Chinese Journal of Pathology 2005;34(4):234-235
Adolescent
;
Adult
;
CD57 Antigens
;
metabolism
;
Diagnosis, Differential
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Female
;
Glial Fibrillary Acidic Protein
;
metabolism
;
Humans
;
Male
;
Middle Aged
;
Neurilemmoma
;
metabolism
;
pathology
;
Pelvic Neoplasms
;
metabolism
;
pathology
;
Peripheral Nervous System Neoplasms
;
metabolism
;
pathology
;
Retroperitoneal Neoplasms
;
metabolism
;
pathology
;
S100 Proteins
;
metabolism
9.Inflammatory Myofibroblastic Tumor on Intercostal Nerve Presenting as Paraneoplastic Pemphigus with Fatal Pulmonary Involvement.
Dong Hyun LEE ; Sun Ho LEE ; Joo Kyung SUNG
Journal of Korean Medical Science 2007;22(4):735-739
Inflammatory myofibroblastic tumors (IMTs) are benign neoplasms that can occur at different anatomic sites with nonspecific clinical symptoms. A 48-yr-old woman presented with a 2-month history of a relapsed oral ulcer, progressive dyspnea, and a thoracic pain induced by breathing. A tumorous mass was noticed in the right costodiaphragmatic recess on chest computed tomography and magnetic resonance imaging, and the patient underwent a right costotransversectomy with excision of the tumor, which originated from the 12th intercostal nerve. Histology and immunohistochemistry showed that the tumor was an IMT of the intercostal nerve. The patient's postoperative course was not favorable; dyspnea persisted after surgery, and a progressive pulmonary compromise developed. The cause of the respiratory failure was found to be bronchiolitis obliterans, which in this case proved to be a fatal complication of paraneoplastic pemphigus associated with an IMT. This case of IMT of the spinal nerve in the paravertebral region is unique in terms of its location and presentation in combination with paraneoplastic pemphigus, which is rare. A brief review of the heterogeneous theories concerning the pathogenesis, clinicopathological features, and differential diagnosis of this disease entity is presented.
Diagnosis, Differential
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Fatal Outcome
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Female
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Granuloma, Plasma Cell/complications/*pathology
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Humans
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Intercostal Nerves/*pathology
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Lung Diseases/etiology/pathology
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Middle Aged
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Paraneoplastic Syndromes/etiology/*pathology
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Pemphigus/etiology/*pathology
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Peripheral Nervous System Neoplasms/complications/*pathology
10.Intraneural hemangioma of the median nerve: report of a case.
Hui LIU ; Qin-he FAN ; Zheng WANG
Chinese Journal of Pathology 2009;38(5):347-348
Antigens, CD34
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metabolism
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Diagnosis, Differential
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Female
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Follow-Up Studies
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Hemangioma
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metabolism
;
pathology
;
surgery
;
Hemangiosarcoma
;
pathology
;
Humans
;
Median Nerve
;
pathology
;
Median Neuropathy
;
metabolism
;
pathology
;
surgery
;
Melanoma
;
pathology
;
Middle Aged
;
Peripheral Nervous System Neoplasms
;
metabolism
;
pathology
;
surgery
;
S100 Proteins
;
metabolism