An analysis of echocardiograms was made in 50 patients with pericardial effusion of various origins, diagnosed by clinical and M-mode echocardiographic examinations. In these cases the estimated volume of pericardial effusion ranged between 40 ml and 999 ml. The width of echo-free space behind the left ventricular wall which reflect the amount of effusion showed a significant positive correlation with the systolic excursion and the diastolic mean velocity of both right and left ventricular epicardial surfaces. The echocardiographic patterns of so-called pseudo-mitral valve prolapse and a notch on the right ventricular epicardial surface during systole were found more frequently in patients with large pericardial effusion. Thus, in pericardial effusion, and echocardiographic examination is useful for the visualization of the abnormal motions of cardiac structures as well as for its diagnosis.
Diagnosis ; Echocardiography* ; Humans ; Pericardial Effusion* ; Prolapse ; Systole

PURPOSE: To compare the clinical and radiological features of aortic intramural hematoma(IMH) to those of acute aortic dissection(AD). MATERIALS AND METHODS: We analyzed the clinical and radiological features of 12patients with aortic IMH and 43 patients with acute AD. In aortic IMH, the diagnoses were made by means of both CTand transesophageal echocardiography (TEE) and included two surgically proven cases. In acute AD, the diagnoses were made by means of CT and TEE and included 21 surgically proven cases. We com- pared patients ages, etiologies, the extent of the disease, the presence or absence of aortic branch involvement, complications, and outcomes. RESULTS: Aortic IMH tended to develop in older patients (67.8+/-7.9 vs. 50.4+/- 13.4, P<.0001) more often than acute AD. In aortic IMH, all patients had a history of hypertension ; in acute AD, hypertension occurred in 37, Marfans syndrome in three, and trauma in one. In aortic IMH, Stanford type A and B lesions were found in four patients (33%) and eight (67%), respectively. In acute AD, Stanford type A and B lesions were seen in 22 (51%) and21 (49%), respectively (p>.05). In aortic IMH, there was no involvement of aortic branches, whereas in acute AD, 14 (33%) patients showed involvement of one or more aortic branches. Complications of aortic IMH included pericardial effusion (n=2) and pleural effusion (n=4) ; in acute AD, pericardial effusion (n=7), pleural effusion(n=4), aortic insufficiency (n=8), cerebral infarction (n=3), renal infarction (n=4) and spinal infarction (n=1)were seen. There was one (8%) death due to aortic IMH and ten (23%) deaths due to acute AD (p<.01). CONCLUSION: Aortic IMH is characterized by its occurrence in older patients with hypertension, a less frequent incidence of complications, and a more favorable outcome than acute AD.
Cerebral Infarction ; Diagnosis ; Echocardiography, Transesophageal ; Hematoma* ; Humans ; Hypertension ; Incidence ; Infarction ; Pericardial Effusion ; Pleural Effusion

PURPOSE: To evaluate the CT findings of tuberculous pericardial effusion. MATERIALS AND METHODS: In 12patients with tuberculous pericardial effusion. CT scans were obtained. The condition was diagnosed by thepresence of chronic granulomatous inflammation with caseous granuloma or acid fast bacilli in a biopsy specimen orpericardial fluid. CT findings were evaluated with regard to the appearance and the location of pericardialthickening, location of pericardial effusion, loculation of the pericardial effusion by adhesion of pericardiumand associated findings such as pulmonary tuberculosis or pleural effusion. RESULTS: In all cases, pericardialeffusion and thickening were seen. This thickening was usually even(10 of 12 cases), and occurred mainly in theanterior portion(7 of 12 cases). Thickened pericardium was enhanced and showed higher attenuation than adjacentchest wall muscle. Effusion was usually found in the anterior portion(10 of 12 cases), though the right and leftside were also involved(5/12 and 6/12 cases, respectively). Loculation of pericardial effusion was noted in tencases. Pleural effusion occurred in eight cases and associated active pulmonary tuberculosis in five. CONCLUSION: The CT findings of tuberculous pericardial effusion are enhanced evenly-thickened pericardium and anteriorloculated pericardial effusion, and are helpful for the diagnosis of tuberculous pericardial effusion.
Biopsy ; Diagnosis ; Granuloma ; Inflammation ; Pericardial Effusion* ; Pericardium ; Pleural Effusion ; Tomography, X-Ray Computed ; Tuberculosis ; Tuberculosis, Pulmonary

Adenosine deaminase(ADA) is an enzyme capable of catalysing the pathway from adenosine to inosine. Previous studies have shown that this enzyme may be useful in recognition of a tubeculous etiology of pleural, peritoneal, or meningeal effusions. ADA activity was studied in 42 patients with large amount of pericardial effusion. Patients were subdivided into the following four group : (A) 15 cases of tuberculous effusions : (B) 4 with pyogenic effusions : (C) 15 with idiopathic effusions : (D) 9 with malignant effusions. The results were as follows ; 1) The mean ADA activities assessed in pericardial effusions were 134.0+/-77.6U/L in group A : 93.8+/-43.8 in group B : 38.3+/-23.2 in group C : 27.3+/-20.8 in group D. Comparing the level achieved in group A with all others, the difference is significant at the P<0.001 level. 2) The mean ADA activities assessed in sera were 50.7+/-57.2 U/L in group A : 63.5+/-24.1 in group B : 25.9+/-12.0 in group C : 14.0+/-7.5 in group D. Comparing the level achieved in group A with all others, there is no significant difference. 3) Specificity(0.87) and sensitivity(0.93) of the test for the differential diagnosis of patients with tuberculous effusion from those with idiopathic effusion is high, when a value of more than 50 U/L is considered. In conclusion, the assessment of ADA in pericardial effusions is of great value in the diagnosis of tuberculous pericarditis.
Adenosine Deaminase* ; Adenosine* ; Diagnosis ; Diagnosis, Differential ; Humans ; Inosine ; Pericardial Effusion* ; Pericarditis, Tuberculous

Cardiac tamponade with pleural and pericardial effusion is a rare but life-threatening complication of umbilical venous catheterization in the newborn. It requires a timely diagnosis and urgent treatment, such as pericardiocentesis, to save lives of affected patients. Recently, we experienced a 7 day-old, very low birth weight infant, who developed a cardiac tamponade with pleural and pericardial effusions complicated by umbilical venous catheterization. The patient was successfully treated with pleural and pericardial drainages. Here, we report this case with a review of literature, since there has been no such previous case reported in Korea.
Cardiac Tamponade* ; Catheterization ; Catheters ; Diagnosis ; Humans ; Infant, Newborn* ; Infant, Very Low Birth Weight ; Korea ; Pericardial Effusion* ; Pericardiocentesis ; Pleural Effusion

BACKGROUND AND OBJECTIVES: The identification of a specific etiology of effusive pericardial disease is difficult because of the limited yield of cytologic and microbiologic pericardial fluid analysis. We performed retrospective study to find out whether pericardial biopsy was superior to pericardial fluid analysis in search of the etiology of pericardial effusion. MATERIALS AND METHOD: We reviewed 76 cases of moderate to severe pericardial effusion on which we performed surgical pericardial biopsy from Sep. 1986 to Sep. 1996. The results of pericardial fluid analysis, clinical manifestation, pericardial biopsy were compared retrospectively. RESULTS: 1)Clinical diagnosis of pericardial effusion were as follow:neoplastic disease (7.9%), tuberculosis (72.4%), constrictive pericarditis (17.1%), and others (2.6%). 2)By the percutaneous pericardial biopsy, we confirmed 19 cases (25%). Etiology of 4 cases (5.3%) were malignancy and 15 cases (19.7%) tuberculosis. Fifteen out of 76 patients who were diagnosed by biopsy as tuberculous pericarditis and 28 patients who were suspected as tuberculous pericarditis clinically were treated with antituberculous medications. Ten patients (66.7%) of pathologically diagnosed patients and 18 patients (69.2%) of clinically diagnosed patients showed complete resolution of pericarditis. CONCLUSION: By pericardial biopsy, we only confirmed 19 cases (25.0%). It means that pericardial biopsy is not superior to pericardial fluid analysis in searching of etiology of pericardial effusion. Moreover, it is not sufficient for final diagnosis of pericardial effusion.
Biopsy* ; Diagnosis ; Humans ; Pericardial Effusion ; Pericarditis ; Pericarditis, Constrictive ; Pericarditis, Tuberculous ; Retrospective Studies ; Tuberculosis

Cardiomegaly is a commonly encountered clinical presentation on simple chest radiographs, and it usually indicates the enlargement of one or more cardiac chambers. However, cardiomegaly less commonly comes from abnormalities in the structures adjacent to the heart, including pericardial effusion, enlarged great vessels, or mediastinal tumors. Pericardial lipoma is a rare primary cardiac tumor that can grow to a large size by the time of diagnosis and result in huge cardiomegaly because of a lack of symptoms. Here, we report a rare case of giant pericardial lipoma that presented as huge cardiomegaly on simple chest radiographs. Multi-modality cardiovascular imaging, including echocardiography and cardiac magnetic resonance imaging, played a key role in the diagnosis and development of a therapeutic treatment plan for the present case.
Cardiomegaly* ; Diagnosis ; Echocardiography ; Heart ; Heart Neoplasms ; Lipoma* ; Magnetic Resonance Imaging ; Pericardial Effusion ; Pericardium ; Radiography, Thoracic

Here, we report a case in which the rapid diagnosis of tuberculous pericarditis was made using Mycobacterium tuberculosis (MTB)-specific interferon-gamma release assay on peripheral blood and pericardial effusion. Acid-fast bacilli staining, mycobacterial culture, and nucleic acid amplification targeting MTB using pericardial fluid were negative. However, elevated adenosine deaminase (ADA) activity in pericardial fluid and interferon-gamma release assay positivity in both pericardial fluid and peripheral blood indicated the presence of tuberculous pericarditis. After anti-tuberculous and steroid treatment, the patient's clinical symptoms improved, and pericardial effusion has not reoccurred.
Adenosine Deaminase ; Diagnosis* ; Interferon-gamma Release Tests* ; Interferon-gamma* ; Mycobacterium tuberculosis ; Pericardial Effusion ; Pericarditis, Tuberculous*

Adolescent ; Child ; Child, Preschool ; Female ; Humans ; Infant ; Male ; Pericardial Effusion ; diagnosis ; etiology ; therapy

Herniation of intra-abdominal contents into the pericardial cavity is rare. We observed a delayed intrapericardial diaphragmatic hernia presenting as a tamponade secondary to a previous pericardioperitoneal window for drainage of a pericardial effusion. The diagnosis of an intrapericardial hernia should be considered in patients presenting with gastrointestinal and/or cardiorespiratory symptoms following surgical procedures involving the diaphragm.
Cardiac Tamponade* ; Diagnosis ; Diaphragm ; Drainage ; Hernia ; Hernia, Diaphragmatic* ; Humans ; Pericardial Effusion